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List of works by Frank Hirth

A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration

scientific article published on 01 October 2018

A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis.

scientific article published in January 2003

Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila.

scientific article published on 7 March 2012

An urbilaterian origin of the tripartite brain: developmental genetic insights from Drosophila.

scientific article published in June 2003

Ancestral regulatory mechanisms specify conserved midbrain circuitry in arthropods and vertebrates

scientific article published on 03 August 2020

Asymmetric stem cell division in development and cancer.

scientific article published on January 2007

C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity

scientific article published on 13 September 2017

Changing pattern in the basal ganglia: motor switching under reduced dopaminergic drive

scientific article published on 23 March 2016

Commissure formation in the embryonic insect brain.

scientific article

Developmental defects in brain segmentation caused by mutations of the homeobox genes orthodenticle and empty spiracles in Drosophila ⬇️

scientific article published on October 1, 1995

Drosophila melanogaster in the study of human neurodegeneration

scientific article

Embryonic development of the Drosophila brain: formation of commissural and descending pathways.

scientific article published in November 1995

Equivalence of the fly orthodenticle gene and the human OTX genes in embryonic brain development of Drosophila.

scientific article published in May 1998

Evolutionarily conserved mechanisms for the selection and maintenance of behavioural activity.

scientific article published on December 2015

Expression and function of the LIM homeodomain protein Apterous during embryonic brain development of Drosophila.

scientific article published on 20 November 2001

Genetic mechanisms regulating stem cell self-renewal and differentiation in the central nervous system of Drosophila

scientific article

Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic

scientific article

Homeotic gene action in embryonic brain development of Drosophila.

scientific article

Homology versus convergence in resolving transphyletic correspondences of brain organization.

scientific article published on 26 November 2013

Hox gene cross-regulatory interactions in the embryonic brain of Drosophila.

scientific article published in June 2004

Immunostaining of the Embryonic and Larval Drosophila Brain

scientific article published on 01 January 2020

Immunostaining of the developing embryonic and larval Drosophila brain.

scientific article published in January 2014

In silico Interrogation of Insect Central Complex Suggests Computational Roles for the Ellipsoid Body in Spatial Navigation

scientific article published on 3 August 2017

In vivo expansion of functionally integrated GABAergic interneurons by targeted increase in neural progenitors.

scientific article published on 4 May 2018

Introduction to 'Homology and convergence in nervous system evolution'

scientific article

Introduction to 'Origin and evolution of the nervous system'

scientific article

Inverse Control of Turning Behavior by Dopamine D1 Receptor Signaling in Columnar and Ring Neurons of the Central Complex in Drosophila

scientific article published on 31 January 2019

Lineage-specific determination of ring neuron circuitry in the central complex of Drosophila

scientific article published on 22 July 2019

Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes

scientific article published on 10 January 2013

Loss of heterozygosity of TRIM3 in malignant gliomas

scientific article

Mechanisms of α-Synuclein Induced Synaptopathy in Parkinson's Disease.

scientific article published on 19 February 2018

Modelling C9ORF72 hexanucleotide repeat expansion in amyotrophic lateral sclerosis and frontotemporal dementia.

scientific article published on 24 December 2013

On the origin and evolution of the tripartite brain.

scientific article published on 30 September 2010

Response to Comment on “The lower Cambrian lobopodian <i>Cardiodictyon</i> resolves the origin of euarthropod brains”

scientific article published on 29 June 2023

TDP-43 loss-of-function causes neuronal loss due to defective steroid receptor-mediated gene program switching in Drosophila

scientific article published on 17 January 2013

The Dopaminergic System in the Aging Brain of Drosophila ⬇️

scientific article published on December 8, 2010

The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila.

scientific article published on 14 June 2006

The columnar gene vnd is required for tritocerebral neuromere formation during embryonic brain development of Drosophila.

scientific article published in November 2006

Thimerosal inhibits Drosophila melanogaster tyrosine hydroxylase (DmTyrH) leading to changes in dopamine levels and impaired motor behavior: implications for neurotoxicity

scientific article published on 01 February 2019

Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila

scientific article published on 07 May 2019

Transcriptional signature of an adult brain tumor in Drosophila

scientific article published on 16 April 2004

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