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List of works by Nick J Reynolds

A Framework for Multi-Omic Prediction of Treatment Response to Biologic Therapy for Psoriasis

scientific article published on 17 July 2018

A randomised placebo controlled trial of anakinra for treating pustular psoriasis: statistical analysis plan for stage two of the APRICOT trial

scientific article published on 10 February 2020

Absence of association between asthma and high serum immunoglobulin E associated GPRA haplotypes and adult atopic dermatitis

scientific article

Agonist-induced calcium entry correlates with STIM1 translocation.

scientific article published on June 2007

Allergic contact dermatitis from a sulfosuccinate derivative in a hand cleanser

scientific article published on 01 January 1990

Allergic contact dermatitis from chlorhexidine diacetate in a skin swab

scientific article published on 01 February 1990

An ancient malady.

scientific article published in December 2006

An observer blinded randomised controlled pilot trial comparing localised immersion psoralen ultraviolet A (PUVA) with localised narrowband ultraviolet B (NBUVB) for the treatment of palmar hand eczema. ⬇️

scientific article published on 13 December 2017

Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein-related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk

scientific article

Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19

scientific article published on 18 October 2021

Association of Serum Ustekinumab Levels With Clinical Response in Psoriasis

scientific article published on 18 September 2019

Azathioprine dosed by thiopurine methyltransferase activity for moderate-to-severe atopic eczema: a double-blind, randomised controlled trial.

scientific article

Azathioprine for atopic dermatitis.

scientific article

British Association of Dermatologists guidelines for use of biological interventions in psoriasis 2005

scientific article published on 19 August 2005

British Association of Dermatologists' guidelines for biologic interventions for psoriasis 2009.

scientific article published in November 2009

British Association of Dermatologists' guidelines for the safe and effective prescribing of azathioprine 2011

scientific article published on 01 October 2011

CARD14 mutations may predict response to antitumour necrosis factor-α therapy in psoriasis: a potential further step towards personalized medicine.

scientific article published in July 2016

CD1 gene expression in human skin

scientific article published on 01 December 1993

Calcineurin inhibitors and sirolimus: mechanisms of action and applications in dermatology.

scientific article

Calcineurin inhibitors for the treatment of skin disease: how do they work?

scientific article published on 01 May 2005

Chronic cutaneous graft-versus-host disease associated with multiple cutaneous squamous cell carcinomas

scientific article published on 01 May 2006

Clinical and pharmacogenetic influences on response to hydroxychloroquine in discoid lupus erythematosus: a retrospective cohort study.

scientific article published on 7 July 2011

Comparative effectiveness of biologic therapies on improvements in quality of life in patients with psoriasis.

scientific article published on 30 March 2017

Cyclosporin A inhibits 12-O-tetradecanoyl-phorbol-13-acetate-induced cutaneous inflammation in severe combined immunodeficient mice that lack functional lymphocytes ⬇️

scientific article published on July 1, 1998

Darkening of white hair in Parkinson's disease

scientific article published on 01 July 1989

Delayed Reaction to Bed Bug Bites ⬇️

scientific article published on February 1, 1992

Demographics and disease characteristics of patients with psoriasis enrolled in the British Association of Dermatologists Biologic Interventions Register.

scientific article published on 18 May 2015

Development and testing of new candidate psoriatic arthritis screening questionnaires combining optimal questions from existing tools

scientific article published in September 2014

Differential Drug Survival of Biologic Therapies for the Treatment of Psoriasis: A Prospective Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

scientific article published on 8 June 2015

Differential Drug Survival of Second-Line Biologic Therapies In Patients with Psoriasis: Observational Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

scientific article

Differential expression of protein kinase C isoenzymes in normal and psoriatic adult human skin: reduced expression of protein kinase C-beta II in psoriasis

scientific article published on 01 October 1993

Discrete Papular Mucinosis Responding to Intralesional and Topical Steroids ⬇️

scientific article published on June 1, 1992

Dissociation of Erythema and p53 Protein Expression in Human Skin Following UVB Irradiation, and Induction of p53 Protein and mRNA Following Application of Skin Irritants

scientific article published on 01 October 1994

Down-regulation of Langerhans cell protein kinase C-beta isoenzyme expression in inflammatory and hyperplastic dermatoses

scientific article published on 01 August 1995

Doxycycline: a first-line treatment for bullous pemphigoid?

scientific article published on 6 March 2017

Effect of oral isotretinoin therapy on saliva volume and composition

scientific article published on 01 August 1991

Elevated expression and genetic association links the SOCS3 gene to atopic dermatitis

scientific article

Enhanced NF-κB signaling in type-2 dendritic cells at baseline predicts non-response to adalimumab in psoriasis

scientific article published on 06 August 2021

Erythema multiforme during danazol therapy

scientific article published on 01 March 1992

Establishing an Academic–Industrial Stratified Medicine Consortium: Psoriasis Stratification to Optimize Relevant Therapy

scientific article published on 01 December 2015

Exfoliative dermatitis due to nifedipine

scientific article published in September 1989

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

scientific article

Feasibility study to inform the design of a UK multi-centre randomised controlled trial of prophylactic antibiotics for the prevention of recurrent cellulitis of the leg

scientific article published on 26 January 2007

Filaggrin haploinsufficiency is highly penetrant and is associated with increased severity of eczema: further delineation of the skin phenotype in a prospective epidemiological study of 792 school children.

scientific article

Filaggrin null mutations and childhood atopic eczema: A population-based case-control study

article

Folliculitis in Down's syndrome

scientific article published on 01 December 1993

Guidelines for prescribing azathioprine in dermatology.

scientific article

Hepatitis: a rare, but important, complication of infliximab therapy for psoriasis

scientific article published on 01 May 2006

High prevalence of alcohol use disorders in patients with inflammatory skin diseases

scientific article published on 27 March 2017

Hydralazine predisposes to acute cutaneous vasculitis following urography with iopamidol.

scientific article

Hydroxyurea in psoriasis

scientific article published on 01 November 1999

Increased nuclear beta-catenin in suprabasal involved psoriatic epidermis

scientific article published on 04 October 2007

Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down.

scientific article published on 11 September 2013

Inhibition of calcium-independent phospholipase A impairs agonist-induced calcium entry in keratinocytes.

scientific article

Keratinocyte apoptosis in epidermal remodeling and clearance of psoriasis induced by UV radiation.

scientific article

Keratinocyte secretion of cyclophilin B via the constitutive pathway is regulated through its cyclosporin-binding site.

scientific article published on 27 January 2011

Kidney disease in moderate-to-severe psoriasis: a critical appraisal.

scientific article

Lithium regulates keratinocyte proliferation via glycogen synthase kinase 3 and NFAT2 (nuclear factor of activated T cells 2) ⬇️

scientific article published on April 1, 2012

Localization of calcineurin/NFAT in human skin and psoriasis and inhibition of calcineurin/NFAT activation in human keratinocytes by cyclosporin A

scientific article (publication date: May 2002)

Lysophosphatidic acid promotes cell migration through STIM1- and Orai1-mediated Ca2+(i) mobilization and NFAT2 activation.

scientific article published on 25 October 2012

Management of psoriasis in pregnancy.

scientific article published in June 2007

Measuring disease activity and damage in cutaneous lupus erythematosus

scientific article published on 01 January 2011

Methotrexate toxicity during treatment of chronic plaque psoriasis: a case report and review of the literature

scientific article

Moving Toward Precision Medicine in Psoriasis and Psoriatic Arthritis

scientific article published on 01 June 2020

NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure.

scientific article

NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma.

scientific article

Narrow-band ultraviolet B and broad-band ultraviolet A phototherapy in adult atopic eczema: a randomised controlled trial.

scientific article

Necrolytic migratory erythema and zinc deficiency

scientific article published on 01 May 1997

Non-Langerhans cell histiocytosis associated with lymphocyte-predominant Hodgkin's disease

scientific article published on 01 September 1999

Null Mutations in the Filaggrin Gene (FLG) Determine Major Susceptibility to Early-Onset Atopic Dermatitis that Persists into Adulthood

article

One hundred and twenty-five years and counting: into an era of systems dermatology

scientific article published in December 2014

PD-1 regulates KLRG1+ group 2 innate lymphoid cells.

scientific article published on 10 May 2017

Patterns of biologic therapy use in the management of psoriasis: cohort study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

scientific article published on 2 September 2016

Persistence and effectiveness of nonbiologic systemic therapies for moderate-to-severe psoriasis in adults: a systematic review

scientific article published on 27 March 2019

Pharmacogenetic screening to prevent carbamazepine-induced toxic epidermal necrolysis and Stevens-Johnson syndrome: a critical appraisal

scientific article published on 01 January 2012

Phosphatidic acid and phospholipase D both stimulate phosphoinositide turnover in cultured human keratinocytes

scientific article published on 01 November 1993

Poised cell circuits in human skin are activated in disease ⬇️

journal article from 'bioRxiv' published in 2020

Predicting response to anti-interleukin 12/23 treatment in psoriasis ⬇️

scientific article published on August 1, 2013

Prevalent and Low-Frequency Null Mutations in the Filaggrin Gene Are Associated with Early-Onset and Persistent Atopic Eczema

article

Proteomic analysis of filaggrin deficiency identifies molecular signatures characteristic of atopic eczema

scientific article published on 28 April 2017

Pruritus secondary to primary biliary cholangitis: a review of the pathophysiology and management with phototherapy

scientific article published on 28 July 2019

Psoriasis occurring after myeloablative therapy and autologous stem cell transplantation

scientific article published on 01 January 2006

Psoriasis treat to target: defining outcomes in psoriasis using data from a real-world, population-based cohort study (the British Association of Dermatologists Biologics and Immunomodulators Register, BADBIR)

scientific article published on 08 July 2019

Psoriatic arthritis screening tools: study design and methodologic challenges - reply from authors.

scientific article published in April 2014

Response to "Comment on: 'When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council'"

scientific article published on 01 August 2018

Risk of Serious Infection in Patients with Psoriasis Receiving Biologic Therapies: A Prospective Cohort Study from the British Association of Dermatologists Biologic Interventions Register (BADBIR).

scientific article

SCH 47112, a novel staurosporine derivative, inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and epidermal hyperplasia in hairless mouse skin

scientific article published on 01 August 1997

Spectral effects of UV on psoriasis

scientific article

The British Association of Dermatologists' Biologic Interventions Register (BADBIR): design, methodology and objectives.

scientific article published on March 2012

The anti-psoriatic drug anthralin accumulates in keratinocyte mitochondria, dissipates mitochondrial membrane potential, and induces apoptosis through a pathway dependent on respiratory competent mitochondria.

scientific article

The c-Rel subunit of NF-κB regulates epidermal homeostasis and promotes skin fibrosis in mice.

scientific article published on 04 April 2013

The devil is in the data: differences in drug persistence between SNIIRAM, the French national health insurance database, and psoriasis biologics intervention registers

scientific article published on 01 January 2019

Tissue kallikrein and kininogen in human sweat glands and psoriatic skin

scientific article published on 01 March 1991

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

scientific journal article

Translating translation into patient benefit for atopic eczema

scientific article published on October 2016

Translocation and downregulation of protein kinase C isoenzymes-alpha and -epsilon by phorbol ester and bryostatin-1 in human keratinocytes and fibroblasts

scientific article published on 01 September 1994

Treatment of moderate-to-severe atopic eczema in adults within the U.K.: results of a national survey of dermatologists.

scientific article published on 11 December 2016

Up-Regulation of p21WAF1 by Phorbol Ester and Calcium in Human Keratinocytes through a Protein Kinase C-Dependent Pathway ⬇️

scientific article published on July 1, 1998

Up-Regulation of p21WAF1/CIP1 in Psoriasis and After the Application of Irritants and Tape Stripping

scientific article published on 01 August 1995

Use of topical glycopyrrolate in Ross syndrome

scientific article published on 01 November 2006

Using Real-World Data to Guide Ustekinumab Dosing Strategies for Psoriasis: A Prospective Pharmacokinetic-Pharmacodynamic Study

scientific article published on 29 January 2020

Ustekinumab exposure during conception and pregnancy in patients with chronic plaque psoriasis: a case series of 10 pregnancies

scientific article published on 04 October 2018

Ustekinumab for severe atopic dermatitis: an important negative study.

scientific article published in August 2017

Weed wacker dermatitis

scientific article published on 01 September 1991

What does the BJD now stand for? A position statement.

scientific article

When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council.

scientific article published on 10 August 2017

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