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List of works by Byron Carpenter

Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces

scientific article published on 5 May 2017

Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein.

scientific article

Crystal structure of rhodopsin in complex with a mini-G sheds light on the principles of G protein selectivity

scientific article published on 19 September 2018

Engineering a minimal G protein to facilitate crystallisation of G protein-coupled receptors in their active conformation.

scientific article

Expression and Purification of Mini G Proteins from Escherichia coli.

scientific article published on April 2017

Expression, Purification and Crystallisation of the Adenosine A2A Receptor Bound to an Engineered Mini G Protein.

scientific article published on April 2017

Human Adenosine A2A Receptor: Molecular Mechanism of Ligand Binding and Activation.

scientific article published on 14 December 2017

Mini G protein probes for active G protein-coupled receptors (GPCRs) in live cells.

scientific article

Mini-G proteins: Novel tools for studying GPCRs in their active conformation

scientific article

PtdIns(4,5)P stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

scientific article published in Nature

Strategy for the Thermostabilization of an Agonist-Bound GPCR Coupled to a G Protein.

scientific article published on 19 July 2017

Structure of the adenosine A(2A) receptor bound to an engineered G protein.

scientific article published on 27 July 2016

Structure of the human obesity receptor leptin-binding domain reveals the mechanism of leptin antagonism by a monoclonal antibody

scientific article

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