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List of works by Jonathan Lou S Esguerra

A circular RNA generated from an intron of the insulin gene controls insulin secretion

scientific article published on 05 November 2020

Argonaute2 mediates compensatory expansion of the pancreatic β cell

scientific article

Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.

scientific article

CD46 Activation Regulates miR-150-Mediated Control of GLUT1 Expression and Cytokine Secretion in Human CD4+ T Cells

scientific article published on 8 January 2016

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

scientific article

Confluence does not affect the expression of miR-375 and its direct targets in rat and human insulin-secreting cell lines.

scientific article published on 28 June 2017

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

scientific article published on 01 February 2019

Differences in islet-enriched miRNAs in healthy and glucose intolerant human subjects

scientific article published on 19 November 2010

Differential glucose-regulation of microRNAs in pancreatic islets of non-obese type 2 diabetes model Goto-Kakizaki rat

scientific article

Dual Effect of Rosuvastatin on Glucose Homeostasis Through Improved Insulin Sensitivity and Reduced Insulin Secretion.

scientific article

Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell

scientific article

Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes.

scientific article

Functional implications of long non-coding RNAs in the pancreatic islets of Langerhans.

scientific article

Functional importance of individual rRNA 2'-O-ribose methylations revealed by high-resolution phenotyping

scientific article published on 6 February 2008

Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism

scientific article

Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

scientific article published on 18 August 2017

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion

scientific article published on 23 January 2019

Islet microRNAs in health and type-2 diabetes

article

Lessons from basic pancreatic beta cell research in type-2 diabetes and vascular complications

scientific article published on 23 January 2017

MiR-335 overexpression impairs insulin secretion through defective priming of insulin vesicles.

scientific article

MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes

scientific article published on 01 May 2020

MicroRNA-7a regulates pancreatic β cell function

scientific article

MicroRNAs in islet hormone secretion

scientific article published on 01 September 2018

Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells

scientific article published on 15 February 2015

Neuron-enriched RNA-binding Proteins Regulate Pancreatic Beta Cell Function and Survival.

scientific article published on 11 January 2017

Nova1 is a master regulator of alternative splicing in pancreatic beta cells.

scientific article

Reduced insulin secretion correlates with decreased expression of exocytotic genes in pancreatic islets from patients with type 2 diabetes.

scientific article published on 23 August 2012

Regulation of Pancreatic Beta Cell Stimulus-Secretion Coupling by microRNAs.

scientific article

Role of non-coding RNAs in pancreatic beta-cell development and physiology

scientific article published on 15 April 2014

Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes

scientific article

Synapsins I and II are not required for insulin secretion from mouse pancreatic β-cells

scientific article

Transcriptional analysis of islets of Langerhans from organ donors of different ages

scientific article published on 12 March 2021

Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis

scientific article

miR-483-5p associates with obesity and insulin resistance and independently associates with new onset diabetes mellitus and cardiovascular disease

scientific article published in PLoS ONE