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List of works by Pedro M Quirós

ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial Activity

Ablation of the stress protease OMA1 protects against heart failure in mice

scientific article published on 01 March 2018

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells

scientific article published on March 2012

Analysis of mtDNA/nDNA Ratio in Mice.

scientific article

Determination of Aconitase Activity: A Substrate of the Mitochondrial Lon Protease

scientific article published in January 2018

Dissecting the early steps of MLL induced leukaemogenic transformation using a mouse model of AML

scientific article published on 16 March 2020

Genetic Regulation of Plasma Lipid Species and Their Association with Metabolic Phenotypes

scientific article published on 13 June 2018

Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice

scientific article published on 22 July 2019

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas

scientific article published on November 2013

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas.

scientific article published on 15 September 2013

Interaction between the ADAMTS-12 metalloprotease and fibulin-2 induces tumor-suppressive effects in breast cancer cells

scientific article

Lon protease: A key enzyme controlling mitochondrial bioenergetics in cancer

scientific article published on October 2014

Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria

scientific article

Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice

scientific article

Metalloproteases and the Degradome

Methionine Restriction Extends Lifespan in Progeroid Mice and Alters Lipid and Bile Acid Metabolism

scientific article published on 01 August 2018

Mitochondria and Epigenetics - Crosstalk in Homeostasis and Stress

scientific article published on 5 March 2017

Mitochondrial Safeguard: a stress response that offsets extreme fusion and protects respiratory function via flickering-induced Oma1 activation

scientific article published on 17 November 2020

Mitohormesis, an Antiaging Paradigm

scientific article published on 21 June 2018

Mitonuclear communication in homeostasis and stress

scientific article published on 9 March 2016

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

scientific article published on 31 May 2017

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia

scientific article

New roles for OMA1 metalloprotease: From mitochondrial proteostasis to metabolic homeostasis

scientific article published on January 2013

New roles for mitochondrial proteases in health, ageing and disease

scientific article published on 13 May 2015

OMA1 mediates OPA1 proteolysis and mitochondrial fragmentation in experimental models of ischemic kidney injury

scientific article

OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial myopathy

scientific article published in 2022

Premature aging in mice activates a systemic metabolic response involving autophagy induction.

scientific article published on 28 April 2008

Proteomic profiling of adipose tissue from Zmpste24-/- mice, a model of lipodystrophy and premature aging, reveals major changes in mitochondrial function and vimentin processing

scientific article published on 9 August 2011

RNAmut: robust identification of somatic mutations in acute myeloid leukemia using RNA-seq

scientific article published on 24 October 2019

Retrograde signals from endosymbiotic organelles: a common control principle in eukaryotic cells

scientific article published on 04 May 2020

Splicing-Directed Therapy in a New Mouse Model of Human Accelerated Aging

article

Supercomplex assembly determines electron flux in the mitochondrial electron transport chain

scientific article

Systems Analyses Reveal Physiological Roles and Genetic Regulators of Liver Lipid Species.

scientific article

Tetracyclines Disturb Mitochondrial Function across Eukaryotic Models: A Call for Caution in Biomedical Research

scientific article

The chromatin remodeling factor ISW-1 integrates organismal responses against nuclear and mitochondrial stress

scientific article published on 28 November 2017

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

scientific article published on 27 April 2016

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