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List of works by Laura Patrussi

Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia

scientific article published on 04 March 2019

Analysis of TCR/CD3 Recycling at the Immune Synapse.

scientific article

Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling

scientific article published on 03 November 2006

Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects

scientific article published on 7 April 2005

Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia.

scientific article

Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells.

scientific article published on August 2016

F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts.

scientific article published in February 2002

Glycerophosphoinositol-4-phosphate enhances SDF-1α-stimulated T-cell chemotaxis through PTK-dependent activation of Vav

scientific article published on 28 July 2007

Inhibition of diacylglycerol kinase α restores restimulation-induced cell death and reduces immunopathology in XLP-1.

scientific article

Nature vs. Nurture: The Two Opposing Behaviors of Cytotoxic T Lymphocytes in the Tumor Microenvironment

scientific article published in 2021

Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc.

scientific article published on 20 February 2014

Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.

scientific article published on 28 October 2004

P66Shc: A Pleiotropic Regulator of B Cell Trafficking and a Gatekeeper in Chronic Lymphocytic Leukemia

scientific article published on 19 April 2020

S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis

scientific article published on 01 October 2012

SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

scientific article published on 2 November 2011

Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.

scientific article

Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases.

scientific article published in November 2006

Specific recycling receptors are targeted to the immune synapse by the intraflagellar transport system

scientific article published on 19 February 2014

The CXCL12/CXCR4 axis as a therapeutic target in cancer and HIV-1 infection.

scientific article

The Glycerophosphoinositols: From Lipid Metabolites to Modulators of T-Cell Signaling ⬇️

scientific article published on July 29, 2013

The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms.

scientific article published on December 2003

The Rab GTPase Rab8 as a shared regulator of ciliogenesis and immune synapse assembly: From a conserved pathway to diverse cellular structures.

scientific article published on 20 November 2015

The small GTPase Rab29 is a common regulator of immune synapse assembly and ciliogenesis

scientific journal article

The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.

scientific article published in June 2015

Themis releases the brakes on TCR signaling during thymocyte selection by disabling SHP-1

scientific article published on 19 June 2017

p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells

scientific article published on 30 May 2007

p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.

scientific article published on February 2004

p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes.

scientific article

p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape

scientific article published on 28 February 2019

p66Shc-dependent apoptosis requires Lck and CamKII activity

scientific article published on 01 February 2012

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