List of works - David J Cousins

A Randomized Placebo-Controlled Trial of Intradermal Grass Pollen Immunotherapy for Seasonal Allergic Rhinitis

scientific article published in February 2016

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

scientific article published in December 2017

Characterisation of P2Y(12) receptor responsiveness to cysteinyl leukotrienes.

scientific article

Chromatin structure and DNA methylation of the IL-4 gene in human T(H)2 cells

scientific article published on 12 June 2009

DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.

scientific article

DNase I footprinting of the human interleukin-5 gene promoter

scientific article published on 01 January 2000

Differential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cells

scientific article published on 08 September 2018

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

scholarly article

Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy

scientific article published on 21 February 2014

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter

scientific article published in PLoS ONE

Fibronectin is a TH1-specific molecule in human subjects.

scientific article

Gene expression profiling of endobronchial ultrasound (EBUS)-derived cytological fine needle aspirates from hilar and mediastinal lymph nodes in non-small cell lung cancer.

scientific article

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production

scientific article

Human TH2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1 ⬇️

scientific article published on March 3, 2012

Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.

scholarly article

Human group 2 innate lymphoid cells do not express the IL-5 receptor.

scientific article published on 10 May 2017

IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.

scientific article

IL-2 regulates expression of C-MAF in human CD4 T cells

scientific article

IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa

scientific article published on 9 December 2015

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo.

scientific article

IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy.

scientific article published on 10 August 2014

Intergenic transcription occurs throughout the human IL-4/IL-13 gene cluster

scientific article published on 01 February 1999

Intradermal grass pollen immunotherapy increases TH2 and IgE responses and worsens respiratory allergic symptoms

scientific article

Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression.

scientific article

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

scientific article published on 12 January 2009

Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens.

scientific article published on 13 January 2017

Pinning allergies on pathogenic TH2 cells.

scientific article

Redefinition of the cleavage sites of DNase I on the nucleosome core particle.

scientific article published in January 2004

Regulation of GM-CSF expression by the transcription factor c-Maf.

scientific article published on 15 May 2007

Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment

scientific article

Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

scientific article

Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

scientific article

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

scientific article published on 7 June 2016

Therapeutic approaches for control of transcription factors in allergic disease.

scientific article published on April 2008

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

scientific article published on 12 November 2014

miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells

scientific article published on 03 August 2018

List of works by David J Cousins

A Randomized Placebo-Controlled Trial of Intradermal Grass Pollen Immunotherapy for Seasonal Allergic Rhinitis

CD1a presentation of endogenous antigens by group 2 innate lymphoid cells.

Characterisation of P2Y(12) receptor responsiveness to cysteinyl leukotrienes.

Chromatin structure and DNA methylation of the IL-4 gene in human T(H)2 cells

DNA methylation changes at human Th2 cytokine genes coincide with DNase I hypersensitive site formation during CD4(+) T cell differentiation.

DNase I footprinting of the human interleukin-5 gene promoter

Differential expression of functional chemokine receptors on human blood and lung group 2 innate lymphoid cells

Diminished sarco/endoplasmic reticulum Ca2+ ATPase (SERCA) expression contributes to airway remodelling in bronchial asthma

Distinct conformations of the chemokine receptor CCR4 with implications for its targeting in allergy

Effects of vitamin D on inflammatory and oxidative stress responses of human bronchial epithelial cells exposed to particulate matter

Fibronectin is a TH1-specific molecule in human subjects.

Gene expression profiling of endobronchial ultrasound (EBUS)-derived cytological fine needle aspirates from hilar and mediastinal lymph nodes in non-small cell lung cancer.

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production

Human TH2 cells respond to cysteinyl leukotrienes through selective expression of cysteinyl leukotriene receptor 1 ⬇️

Human Th2 cells selectively express the orexigenic peptide, pro-melanin-concentrating hormone.

Human group 2 innate lymphoid cells do not express the IL-5 receptor.

IFN-gamma gene expression is controlled by the architectural transcription factor HMGA1.

IL-2 regulates expression of C-MAF in human CD4 T cells

IL-25/IL-33-responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa

IL-33-dependent type 2 inflammation during rhinovirus-induced asthma exacerbations in vivo.

IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy.

Intergenic transcription occurs throughout the human IL-4/IL-13 gene cluster

Intradermal grass pollen immunotherapy increases TH2 and IgE responses and worsens respiratory allergic symptoms

Leukotriene E4 is a full functional agonist for human cysteinyl leukotriene type 1 receptor-dependent gene expression.

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

Mucosal Type 2 Innate Lymphoid Cells Are a Key Component of the Allergic Response to Aeroallergens.

Pinning allergies on pathogenic TH2 cells.

Redefinition of the cleavage sites of DNase I on the nucleosome core particle.

Regulation of GM-CSF expression by the transcription factor c-Maf.

Repression of interleukin-5 transcription by the glucocorticoid receptor targets GATA3 signaling and involves histone deacetylase recruitment

Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

Sphingosine-1-phosphate induces pro-remodelling response in airway smooth muscle cells

T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex

Therapeutic approaches for control of transcription factors in allergic disease.

Vitamin D enhances production of soluble ST2, inhibiting the action of IL-33.

miR-29b directly targets activation-induced cytidine deaminase in human B cells and can limit its inappropriate expression in naïve B cells