List of works - David Stoltz

A common mutation in paraoxonase-2 results in impaired lactonase activity.

scientific article published on December 2009

Abundant DNase I-Sensitive Bacterial DNA in Healthy Porcine Lungs and Its Implications for the Lung Microbiome ⬇️

scientific article published on July 19, 2013

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

scientific article

Acidic pH increases airway surface liquid viscosity in cystic fibrosis

scientific article published on 25 January 2016

Acute ethanol intoxication inhibits neutrophil beta2-integrin expression in rats during endotoxemia

scientific article published on 01 February 1998

Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model

scientific article

Adenoviral-Mediated Interferon-gamma Gene Therapy Augments Pulmonary Host Defense of Ethanol-Treated Rats ⬇️

scientific article published on February 1, 1998

Air trapping and airflow obstruction in newborn cystic fibrosis piglets

scientific article published on December 2013

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

scientific article published on January 2016

Antibacterial properties of the CFTR potentiator ivacaftor

scientific article

Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs

scientific article

CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia

scientific article

Calcium and the effects of ultrasound on frog skin

scientific article published on 01 January 1994

Computer-aided analysis of airway trees in micro-CT scans of ex vivo porcine lung tissue.

scientific article published on 7 September 2012

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

scientific article published on 18 February 2011

Cystic Fibrosis Transmembrane Conductance Regulator Intracellular Processing, Trafficking, and Opportunities for Mutation-Specific Treatment ⬇️

scientific article published on June 1, 2011

Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.

scientific article

Cystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway Contractility

scientific article published on 21 October 2015

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

scientific article

Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

scientific article

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

scientific article published on September 2008

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1.

scientific article published on September 2008

Early airway structural changes in cystic fibrosis pigs as a determinant of particle distribution and deposition.

scientific article

Effect of free radical scavengers on changes in ion conductance during exposure to therapeutic ultrasound

scientific article published on 01 October 1993

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

scientific article published on 22 January 2016

Enhancement of peritoneal leukocyte function by granulocyte colony-stimulating factor in rats with abdominal sepsis

scientific article published on 01 February 1998

Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster

scientific article

Gel-forming mucins form distinct morphologic structures in airways

scientific article

Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets ⬇️

scientific article published on 31 October 2013

Glucose depletion in the airway surface liquid is essential for sterility of the airways

scientific article (publication date: 2011)

Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass.

scientific article

Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of acute ethanol intoxication

scientific article published on 01 June 1999

Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.

scientific article published on July 2003

Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans

scientific article published on 27 October 2015

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.

scientific article published on August 2014

Inhaled hypertonic saline in adults hospitalised for exacerbation of cystic fibrosis lung disease: a retrospective study.

scientific article published on 19 April 2012

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

scientific article published on 8 May 2013

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.

scientific article published on 21 February 2018

Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children

scientific article

Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor

scientific article

Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.

scientific article published on April 2017

Mounier-Kuhn syndrome: a case of tracheal smooth muscle remodeling.

scientific article published on 29 December 2016

Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways

scientific article published on 01 November 2018

Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study

scientific article

Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus

scientific article

Origins of cystic fibrosis lung disease

scientific article

Origins of cystic fibrosis lung disease

scientific article published on 01 April 2015

Pancreatic and biliary secretion are both altered in cystic fibrosis pigs.

scientific article

Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways

scientific article

Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth

scientific article

Postnatal airway growth in cystic fibrosis piglets

scientific article published on 15 June 2017

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

scientific article

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

scientific article

Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.

scientific article published on 21 February 2017

Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model

scientific article published on 06 January 2014

Role of poliovirus receptors in the spread of the infection

scientific article published on 01 May 1995

Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis

scientific article

Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis.

scientific article

Suppression of the granulocyte colony-stimulating factor response to Escherichia coli challenge by alcohol intoxication

scientific journal article

The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques.

scientific article published in March 2003

The porcine lung as a potential model for cystic fibrosis

scientific article published on 16 May 2008

The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs

scientific article

Tracheomalacia is associated with lower FEV1 and Pseudomonas acquisition in children with CF

scientific article

Use of granulocyte colony-stimulating factor in the treatment of acute infectious diseases ⬇️

scientific article published on May 1, 1997

V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells

scientific article published in 2021

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37

scientific article

List of works by David Stoltz

A common mutation in paraoxonase-2 results in impaired lactonase activity.

Abundant DNase I-Sensitive Bacterial DNA in Healthy Porcine Lungs and Its Implications for the Lung Microbiome ⬇️

Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice

Acidic pH increases airway surface liquid viscosity in cystic fibrosis

Acute ethanol intoxication inhibits neutrophil beta2-integrin expression in rats during endotoxemia

Adenoviral gene transfer corrects the ion transport defect in the sinus epithelia of a porcine CF model

Adenoviral-Mediated Interferon-gamma Gene Therapy Augments Pulmonary Host Defense of Ethanol-Treated Rats ⬇️

Air trapping and airflow obstruction in newborn cystic fibrosis piglets

Airway acidification initiates host defense abnormalities in cystic fibrosis mice.

Antibacterial properties of the CFTR potentiator ivacaftor

Assessing mucociliary transport of single particles in vivo shows variable speed and preference for the ventral trachea in newborn pigs

CFTR is required for maximal transepithelial liquid transport in pig alveolar epithelia

Calcium and the effects of ultrasound on frog skin

Computer-aided analysis of airway trees in micro-CT scans of ex vivo porcine lung tissue.

Concentration of the antibacterial precursor thiocyanate in cystic fibrosis airway secretions

Cystic Fibrosis Transmembrane Conductance Regulator Intracellular Processing, Trafficking, and Opportunities for Mutation-Specific Treatment ⬇️

Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs.

Cystic Fibrosis Transmembrane Conductance Regulator in Sarcoplasmic Reticulum of Airway Smooth Muscle. Implications for Airway Contractility

Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth

Delayed neutrophil apoptosis enhances NET formation in cystic fibrosis

Disruption of the CFTR gene produces a model of cystic fibrosis in newborn pigs

Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1.

Early airway structural changes in cystic fibrosis pigs as a determinant of particle distribution and deposition.

Effect of free radical scavengers on changes in ion conductance during exposure to therapeutic ultrasound

Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense

Enhancement of peritoneal leukocyte function by granulocyte colony-stimulating factor in rats with abdominal sepsis

Expression of human paraoxonase 1 decreases superoxide levels and alters bacterial colonization in the gut of Drosophila melanogaster

Gel-forming mucins form distinct morphologic structures in airways

Genotype-specific alterations in vascular smooth muscle cell function in cystic fibrosis piglets ⬇️

Glucose depletion in the airway surface liquid is essential for sterility of the airways

Glycaemic regulation and insulin secretion are abnormal in cystic fibrosis pigs despite sparing of islet cell mass.

Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of acute ethanol intoxication

Histamine alters E-cadherin cell adhesion to increase human airway epithelial permeability.

Immunohistochemical Detection of Markers for Translational Studies of Lung Disease in Pigs and Humans

Impaired mucus detachment disrupts mucociliary transport in a piglet model of cystic fibrosis.

Inhaled hypertonic saline in adults hospitalised for exacerbation of cystic fibrosis lung disease: a retrospective study.

Intestinal CFTR expression alleviates meconium ileus in cystic fibrosis pigs

Lack of cystic fibrosis transmembrane conductance regulator disrupts fetal airway development in pigs.

Loss of cystic fibrosis transmembrane conductance regulator function produces abnormalities in tracheal development in neonatal pigs and young children

Medical reversal of chronic sinusitis in a cystic fibrosis patient with ivacaftor

Monocyte derived macrophages from CF pigs exhibit increased inflammatory responses at birth.

Mounier-Kuhn syndrome: a case of tracheal smooth muscle remodeling.

Mucociliary Transport in Healthy and Cystic Fibrosis Pig Airways

Neonates with cystic fibrosis have a reduced nasal liquid pH; a small pilot study

Newborn Cystic Fibrosis Pigs Have a Blunted Early Response to an Inflammatory Stimulus

Origins of cystic fibrosis lung disease

Origins of cystic fibrosis lung disease

Pancreatic and biliary secretion are both altered in cystic fibrosis pigs.

Pancreatic damage in fetal and newborn cystic fibrosis pigs involves the activation of inflammatory and remodeling pathways

Pigs and humans with cystic fibrosis have reduced insulin-like growth factor 1 (IGF1) levels at birth

Postnatal airway growth in cystic fibrosis piglets

Production of CFTR-null and CFTR-DeltaF508 heterozygous pigs by adeno-associated virus-mediated gene targeting and somatic cell nuclear transfer

Reduced airway surface pH impairs bacterial killing in the porcine cystic fibrosis lung

Restoring Cystic Fibrosis Transmembrane Conductance Regulator Function Reduces Airway Bacteria and Inflammation in People with Cystic Fibrosis and Chronic Lung Infections.

Role of PON in anoxia-reoxygenation injury: a Drosophila melanogaster transgenic model

Role of poliovirus receptors in the spread of the infection

Sinus hypoplasia precedes sinus infection in a porcine model of cystic fibrosis

Sonographic evidence of abnormal tracheal cartilage ring structure in cystic fibrosis.

Suppression of the granulocyte colony-stimulating factor response to Escherichia coli challenge by alcohol intoxication

The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques.

The porcine lung as a potential model for cystic fibrosis

The ΔF508 mutation causes CFTR misprocessing and cystic fibrosis-like disease in pigs

Tracheomalacia is associated with lower FEV1 and Pseudomonas acquisition in children with CF

Use of granulocyte colony-stimulating factor in the treatment of acute infectious diseases ⬇️

V-Type ATPase Mediates Airway Surface Liquid Acidification in Pig Small Airway Epithelial Cells

pH modulates the activity and synergism of the airway surface liquid antimicrobials β-defensin-3 and LL-37