List of works - Christopher J Lynch

A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.

scientific article

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis

scientific article

A report of activities related to the Dietary Reference Intakes from the Joint Canada-US Dietary Reference Intakes Working Group

article

Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.

scientific article

Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase

scientific journal article

BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.

scientific article

Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity

scientific article

Characterization of the pharmacological-sensitivity profile of neoglycoprotein-induced acrosome reaction in mouse spermatozoa

scientific article published on 01 September 1999

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

scientific journal article

Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice

scientific article published on 04 August 2010

Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.

scientific article

Functional proteomic analysis reveals sex-dependent differences in structural and energy-producing myocardial proteins in rat model of alcoholic cardiomyopathy

scientific article

Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats

scientific article

Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

scientific article

Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat.

scientific article

Impact of chronic alcohol ingestion on cardiac muscle protein expression

scientific article

Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.

scientific article

Leucine and protein metabolism in obese Zucker rats

scientific article

Leucine in food mediates some of the postprandial rise in plasma leptin concentrations

scientific article published on 25 April 2006

Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice

scientific article

Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

scientific article published on November 2005

Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease ⬇️

scientific article published on April 19, 2011

Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle.

scientific article published on 10 May 2005

Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.

scientific article published on 09 October 2007

Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.

scientific article

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

scientific article published on June 2009

Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle

scientific article published on 27 March 2007

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

scientific article published on 01 March 2000

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

scientific article

Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.

scientific article published on 13 December 2011

Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion* ⬇️

scientific article published on August 24, 2010

List of works by Christopher J Lynch

A double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.

A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis

A report of activities related to the Dietary Reference Intakes from the Joint Canada-US Dietary Reference Intakes Working Group

Adipose tissue branched chain amino acid (BCAA) metabolism modulates circulating BCAA levels.

Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase

BCATm deficiency ameliorates endotoxin-induced decrease in muscle protein synthesis and improves survival in septic mice.

Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity

Characterization of the pharmacological-sensitivity profile of neoglycoprotein-induced acrosome reaction in mouse spermatozoa

Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle

Effect of the tyrosine kinase inhibitors (sunitinib, sorafenib, dasatinib, and imatinib) on blood glucose levels in diabetic and nondiabetic patients in general clinical practice

Erythropoietin modulation of intracellular calcium: a role for tyrosine phosphorylation.

Functional proteomic analysis reveals sex-dependent differences in structural and energy-producing myocardial proteins in rat model of alcoholic cardiomyopathy

Gastric bypass surgery alters behavioral and neural taste functions for sweet taste in obese rats

Global deletion of BCATm increases expression of skeletal muscle genes associated with protein turnover

Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat.

Impact of chronic alcohol ingestion on cardiac muscle protein expression

Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.

Leucine and protein metabolism in obese Zucker rats

Leucine in food mediates some of the postprandial rise in plasma leptin concentrations

Leucine supplementation of drinking water does not alter susceptibility to diet-induced obesity in mice

Meal feeding enhances formation of eIF4F in skeletal muscle: role of increased eIF4E availability and eIF4G phosphorylation.

Molecular characterization of skeletal muscle atrophy in the R6/2 mouse model of Huntington's disease ⬇️

Nutrient regulation of PKCepsilon is mediated by leucine, not insulin, in skeletal muscle.

Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.

Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle

Regulation of amino acid-sensitive TOR signaling by leucine analogues in adipocytes

Skeletal muscle protein balance in mTOR heterozygous mice in response to inflammation and leucine

Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.

Transamination Is Required for α-Ketoisocaproate but Not Leucine to Stimulate Insulin Secretion* ⬇️