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List of works by Debasis Patnaik

A positive feedback loop involving Haspin and Aurora B promotes CPC accumulation at centromeres in mitosis

scientific article

Brain-penetrant LSD1 inhibitors can block memory consolidation.

scientific article

Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.

scientific article published on March 2006

Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.

scientific article published on 2 February 2017

Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging.

scientific article

Discovery of suppressors of CRMP2 phosphorylation reveals compounds that mimic the behavioral effects of lithium on amphetamine-induced hyperlocomotion

scientific article published on 24 February 2020

Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation

scientific article published on 11 January 2016

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

scientific article published on 30 September 2004

Dual histone H3 methylation marks at lysines 9 and 27 required for interaction with CHROMOMETHYLASE3.

scientific article published in May 2011

Exifone Is a Potent HDAC1 Activator with Neuroprotective Activity in Human Neuronal Models of Neurodegeneration

scientific article published on 08 January 2021

Functional analysis of the N- and C-terminus of mammalian G9a histone H3 methyltransferase

scientific article

Genetic transformation of Indian bread (T. aestivum) and pasta (T. durum) wheat by particle bombardment of mature embryo-derived calli

scientific article

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease

scientific article published on 18 May 2020

Haspin inhibitors reveal centromeric functions of Aurora B in chromosome segregation

scientific article

Identification and Mechanistic Characterization of a Peptide Inhibitor of Glycogen Synthase Kinase (GSK3β) Derived from the Disrupted in Schizophrenia 1 (DISC1) Protein

scientific article published on 30 November 2020

Identification of small molecule inhibitors of the mitotic kinase haspin by high-throughput screening using a homogeneous time-resolved fluorescence resonance energy transfer assay ⬇️

scientific article

Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects

scientific article

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?

scientific article

Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase.

scientific article published in October 2005

Structure and functional characterization of the atypical human kinase haspin

scientific article

Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.

scientific article published on June 2010

Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors.

scientific article published on 28 January 2012

Structure-based screening of chemical libraries to identify small molecules that are likely to bind with the SET and RING-associated (SRA) domain of Ubiquitin-like, PHD and Ring Finger-containing 1 (UHRF1)

scientific article published on 24 May 2020

Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.

scientific article published on 25 May 2018

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