List of works by Shigeru Kakuta

A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens

scientific article

Adenocarcinoma of Barrett's esophagus in a dog.

scientific article published on 29 April 2017

C-type lectin MCL is an FcRγ-coupled receptor that mediates the adjuvanticity of mycobacterial cord factor

scientific journal article

CCR8 regulates contact hypersensitivity by restricting cutaneous dendritic cell migration to the draining lymph nodes

scientific article published on 25 October 2014

CTRP3 plays an important role in the development of collagen-induced arthritis in mice.

scientific article

CTRP6 is an endogenous complement regulator that can effectively treat induced arthritis

scientific article

Chemokine receptor CCR8 is required for lipopolysaccharide-triggered cytokine production in mouse peritoneal macrophages

scientific article (publication date: 2014)

Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans

scientific journal article

Establishment and analysis of a novel mouse line carrying a conditional knockin allele of a cancer-specific FBXW7 mutation

scientific article published on 31 January 2018

Exacerbation of experimental autoimmune encephalomyelitis in mice deficient for DCIR, an inhibitory C-type lectin receptor.

scientific article published on January 2015

Gene targeting study reveals unexpected expression of brain-expressed X-linked 2 in endocrine and tissue stem/progenitor cells in mice

scientific article

Generation of a mouse model with down-regulated U50 snoRNA (SNORD50) expression and its organ-specific phenotypic modulation

scientific article (publication date: 2013)

Genetic background and gender effects on gross phenotypes in congenic lines of ALS2/alsin-deficient mice.

scientific article

Herpes simplex virus-1 evasion of CD8+ T cell accumulation contributes to viral encephalitis.

scientific article published on 11 September 2017

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells

scientific article published on 25 June 2015

IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages

scientific article published on 27 February 2015

In vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling

scientific article

Inhibition of Dectin-1 Signaling Ameliorates Colitis by Inducing Lactobacillus-Mediated Regulatory T Cell Expansion in the Intestine

scientific article

Involvement of interleukin-1 type 1 receptors in lipopolysaccharide-induced sickness responses

scientific article published on 24 June 2017

Kjellmaniella crassifolia Miyabe (Gagome) extract modulates intestinal and systemic immune responses

scientific article published on 7 November 2011

N-methyl-d-aspartate receptor coagonist d-serine suppresses intake of high-preference food

scientific article published on 8 July 2015

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons

scientific article

Orally administered brown seaweed-derived β-glucan effectively restrained development of gastric dysplasia in A4gnt KO mice that spontaneously develop gastric adenocarcinoma.

scientific article

Pre-Transplantation Blockade of TNF-α-Mediated Oxygen Species Accumulation Protects Hematopoietic Stem Cells

scientific article published on 18 October 2016

Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis

scientific article

Stage-specific roles for CXCR4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation

scientific article published in July 2014

Suppression of IL-17F, but not of IL-17A, provides protection against colitis by inducing Treg cells through modification of the intestinal microbiota

scientific article published on 18 June 2018

The essential role of phospho-T38 CPI-17 in the maintenance of physiological blood pressure using genetically modified mice.

scientific article published on 11 December 2017

The potential for repositioning antithyroid agents as antiasthma drugs

scientific article published on 15 June 2016

Upregulation of Polymeric Immunoglobulin Receptor Expression by the Heat-Inactivated Potential Probiotic Bifidobacterium bifidum OLB6378 in a Mouse Intestinal Explant Model

article

Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complex

scientific journal article

Visceral Adipose Tissue-derived Serine Proteinase Inhibitor Inhibits Apoptosis of Endothelial Cells as a Ligand for the Cell-Surface GRP78/Voltage-dependent Anion Channel Complex

scientific article published on 10 January 2013

Visualization of Probiotic-Mediated Ca2+ Signaling in Intestinal Epithelial Cells In Vivo

scientific article

Zygote-mediated generation of genome-modified mice using Streptococcus thermophilus 1-derived CRISPR/Cas system.

scientific article published on 15 June 2016