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List of works by Jerome C Nwachukwu

Bicyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfonamides.

scientific article

Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling

scientific article published on 28 January 2021

Creb coactivators direct anabolic responses and enhance performance of skeletal muscle

scientific journal article

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements.

scientific article published on 6 April 2018

Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis

scientific article published on January 2015

Full antagonism of the estrogen receptor without a prototypical ligand side chain

scientific article

Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells

scientific article

Identification and structure-activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2.2.1]hept-2-ene-7-oxide.

scientific article published on 21 February 2012

Improved crystallographic structures using extensive combinatorial refinement

scientific article

Ligand-binding dynamics rewire cellular signaling via estrogen receptor-α ⬇️

scientific article published on March 24, 2013

Native top-down proteomics reveals EGFR-ERα signaling crosstalk in breast cancer cells dissociates NUTF2 dimers to modulate ERα signaling and cell growth

scientific article published on 24 July 2023

Predictive features of ligand-specific signaling through the estrogen receptor

scientific article

Regulation of androgen receptor-mediated transcription by RPB5 binding protein URI/RMP

scientific article

Resveratrol modulates the inflammatory response via an estrogen receptor-signal integration network

scientific article

Structural Mechanisms of Allostery and Autoinhibition in JNK Family Kinases

scientific article

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers.

scientific article

The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells.

scientific article published on 29 November 2018

The nuclear receptor signalling scaffold: insights from full-length structures.

scientific article published on 18 January 2012

Thiophene-core estrogen receptor ligands having superagonist activity.

scientific article published on 15 April 2013

Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor.

scientific article published on 07 April 2014

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