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List of works by Neeraj Dhar

2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1

scientific article

4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity

scientific article

A lung-on-chip model of early M. tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth

scientific article published on 24 November 2020

An Amidase_3 domain-containing N-acetylmuramyl-L-alanine amidase is required for mycobacterial cell division

scientific article

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor

scientific article published on 08 May 2016

Assessing the essentiality of the decaprenyl-phospho-d-arabinofuranose pathway in Mycobacterium tuberculosis using conditional mutants

scientific article published on 7 March 2014

Benzothiazinones kill Mycobacterium tuberculosis by blocking arabinan synthesis

scientific journal article

Bioluminescence for assessing drug potency against nonreplicating Mycobacterium tuberculosis

scientific article published on 20 April 2015

Boosting with a DNA vaccine expressing ESAT-6 (DNAE6) obliterates the protection imparted by recombinant BCG (rBCGE6) against aerosol Mycobacterium tuberculosis infection in guinea pigs.

scientific article

Combinations of β-Lactam Antibiotics Currently in Clinical Trials Are Efficacious in a DHP-I-Deficient Mouse Model of Tuberculosis Infection

scientific article published on 18 May 2015

Computational Analysis of the Mutual Constraints between Single-Cell Growth and Division Control Models

scientific article published on 16 December 2019

Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism.

scientific article

Development of a repressible mycobacterial promoter system based on two transcriptional repressors

scientific article published on 20 April 2010

Dielectrophoresis-based purification of antibiotic-treated bacterial subpopulations.

scientific article published on 23 April 2014

Disruption of mptpB impairs the ability of Mycobacterium tuberculosis to survive in guinea pigs.

scientific article published in November 2003

Division site selection linked to inherited cell surface wave troughs in mycobacteria.

scientific article

Driving polar growth

scientific article published on 07 May 2020

Dynamic persistence of antibiotic-stressed mycobacteria

scientific article published on 01 January 2013

Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model

scientific article published on 21 July 2021

Elucidating the role of (p)ppGpp in mycobacterial persistence against antibiotics

scientific article published on 09 August 2018

Enhanced and enduring protection against tuberculosis by recombinant BCG-Ag85C and its association with modulation of cytokine profile in lung

scientific article

Erratum for Boldrin et al., The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo.

scientific article published in December 2014

EspD is critical for the virulence-mediating ESX-1 secretion system in Mycobacterium tuberculosis.

scientific article published on 9 December 2011

EspI regulates the ESX-1 secretion system in response to ATP levels in Mycobacterium tuberculosis

scientific article

Identification of aminopyrimidine-sulfonamides as potent modulators of Wag31-mediated cell elongation in mycobacteria

scientific article published on 28 September 2016

Immunogenicity of recombinant BCG vaccine strains overexpressing components of the antigen 85 complex of Mycobacterium tuberculosis

scientific article published on 02 August 2003

In vitro and in vivo activities of three oxazolidinones against nonreplicating Mycobacterium tuberculosis

scientific article

Increased expression of Mycobacterium tuberculosis 19 kDa lipoprotein obliterates the protective efficacy of BCG by polarizing host immune responses to the Th2 subtype.

scientific article published in May 2005

Malachite Green Interferes with Postantibiotic Recovery of Mycobacteria ⬇️

scientific article published on April 23, 2012

Microbial phenotypic heterogeneity and antibiotic tolerance.

scientific article published on 9 January 2007

Modulation of host immune responses by overexpression of immunodominant antigens of Mycobacterium tuberculosis in bacille Calmette-Guérin

scientific article published on 01 October 2003

Mycobacterium tuberculosis EspB binds phospholipids and mediates EsxA-independent virulence.

scientific article published on 15 August 2013

Nanoparticle conjugation and pulmonary delivery enhance the protective efficacy of Ag85B and CpG against tuberculosis

scientific article published on 23 July 2011

Phenotypic profiling of Mycobacterium tuberculosis EspA point mutants reveals that blockage of ESAT-6 and CFP-10 secretion in vitro does not always correlate with attenuation of virulence.

scientific article published on 27 September 2013

Preexisting variation in DNA damage response predicts the fate of single mycobacteria under stress

scientific article published on 04 October 2019

Rapid cytolysis of Mycobacterium tuberculosis by faropenem, an orally bioavailable β-lactam antibiotic

scientific article

Recombinant BCG approach for development of vaccines: cloning and expression of immunodominant antigens of M. tuberculosis

scientific article published on 01 September 2000

Simple and rapid method to determine antimycobacterial potency of compounds by using autoluminescent Mycobacterium tuberculosis

scientific article

Simple model for testing drugs against nonreplicating Mycobacterium tuberculosis

scientific article

Single-cell analysis of mycobacteria using microfluidics and time-lapse microscopy

scientific article published in January 2015

Single-cell dynamics of the chromosome replication and cell division cycles in mycobacteria

scientific article

Skewing of the Th1/Th2 responses in mice due to variation in the level of expression of an antigen in a recombinant BCG system

scientific article published on 01 September 2003

Streptomycin-starved Mycobacterium tuberculosis 18b, a drug discovery tool for latent tuberculosis

scientific article

Stress and host immunity amplify Mycobacterium tuberculosis phenotypic heterogeneity and induce nongrowing metabolically active forms.

scientific article published on 24 December 2014

Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells

scientific article published on 22 January 2015

Structural Basis for Benzothiazinone-Mediated Killing of Mycobacterium tuberculosis

scientific article

The phosphatidyl-myo-inositol mannosyltransferase PimA is essential for Mycobacterium tuberculosis growth in vitro and in vivo

scientific article

Whole Cell Target Engagement Identifies Novel Inhibitors of Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase

scientific article published on 25 August 2015

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