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List of works by Benjamin G Hale

A Transient Homotypic Interaction Model for the Influenza A Virus NS1 Protein Effector Domain

scientific article

A single amino acid substitution in the novel H7N9 influenza A virus NS1 protein increases CPSF30 binding and virulence.

scientific article published on 30 July 2014

An antiviral trap made of protein nanofibrils and iron oxyhydroxide nanoparticles

scientific article published on 3 June 2021

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

scientific article published on 07 August 2019

Antigen presentation kinetics control T cell/dendritic cell interactions and follicular helper T cell generation in vivo.

scientific article

Antiviral Activity of Type I, II, and III Interferons Counterbalances ACE2 Inducibility and Restricts SARS-CoV-2

scientific article published on 10 September 2020

Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential

scientific article published on 26 August 2020

BRD9 is a druggable component of interferon-stimulated gene expression and antiviral activity

scientific article published on 16 August 2021

Binding of influenza A virus NS1 protein to the inter-SH2 domain of p85 suggests a novel mechanism for phosphoinositide 3-kinase activation

scientific article published on 20 November 2007

CDK/ERK-mediated phosphorylation of the human influenza A virus NS1 protein at threonine-215.

scientific article

Cation currents in human airway epithelial cells induced by infection with influenza A virus.

scientific article published on 29 April 2009

Conformational plasticity of the influenza A virus NS1 protein

scientific article

Contribution of NS1 effector domain dimerization to influenza A virus replication and virulence

scientific article

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species

scientific article

Functional Insights into ANP32A-Dependent Influenza A Virus Polymerase Host Restriction.

scientific article published on September 2017

Global Reprogramming of Host SUMOylation during Influenza Virus Infection.

scientific article

Human interactome of the influenza B virus NS1 protein.

scientific article published on 4 September 2017

Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

scientific article

Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

scientific article

Influenza A viruses and PI3K: are there time, place and manner restrictions?

scientific article published on 22 June 2012

Influenza virus sequence feature variant type analysis: evidence of a role for NS1 in influenza virus host range restriction.

scientific article published on 7 March 2012

Innate immune evasion strategies of influenza viruses

scientific article

Interplay between viruses and host sumoylation pathways

scientific article published on 29 April 2013

MHC class II proteins mediate cross-species entry of bat influenza viruses

scientific article published in Nature

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus.

scientific article

Novel Bat Influenza Virus NS1 Proteins Bind Double-Stranded RNA and Antagonize Host Innate Immunity

scientific article

Profiling host ANP32A splicing landscapes to predict influenza A virus polymerase adaptation

scientific article published on 30 July 2019

Proximal protein landscapes of the type I interferon signaling cascade reveal negative regulation by PJA2

scientific article published in 2024

Species-specific antagonism of host ISGylation by the influenza B virus NS1 protein

scientific article

Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence

scientific article

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

scientific article

Structure of an avian influenza A virus NS1 protein effector domain

scientific article

Structure-Guided Functional Annotation of the Influenza A Virus NS1 Protein Reveals Dynamic Evolution of the p85β-Binding Site During Circulation in Humans

scientific article

The multifunctional NS1 protein of influenza A viruses

scientific article

Unexpected Functional Divergence of Bat Influenza Virus NS1 Proteins

scientific article published on 13 December 2017

Viral and Host Factors Required for Avian H5N1 Influenza A Virus Replication in Mammalian Cells ⬇️

scientific article published on June 10, 2013

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