List of works - Imo Hoefer

3D black blood VISTA vessel wall cardiovascular magnetic resonance of the thoracic aorta wall in young, healthy adults: reproducibility and implications for efficacy trial sample sizes: a cross-sectional study

scientific article published on 14 April 2016

A fibronectin‐fibrinogen‐tropoelastin coating reduces smooth muscle cell growth but improves endothelial cell function ⬇️

scientific article published on September 1, 2012

A membrane-based microfluidic device for mechano-chemical cell manipulation

scientific article published on April 2016

A new intra-arterial delivery platform for pro-arteriogenic compounds to stimulate collateral artery growth via transforming growth factor-beta1 release

scientific article published on 10 July 2007

A single preoperative blood test predicts postoperative sepsis and pneumonia after coronary bypass or open aneurysm surgery

scientific article published on 04 January 2019

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

scientific article

Admittance-based pressure-volume loops versus gold standard cardiac magnetic resonance imaging in a porcine model of myocardial infarction

scientific article published on 22 April 2014

Arteriogenesis proceeds via ICAM-1/Mac-1- mediated mechanisms

scientific article published in April 2004

Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion

scientific article (publication date: 20 September 2005)

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

scientific article published on 21 March 2019

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

scientific article published on 13 July 2020

Beyond the matrix: MMP2 as critical regulator of inflammation-mediated vascular dysfunction

scientific article published on 13 October 2017

Biobanks and the search for predictive biomarkers of local and systemic outcome in atherosclerotic disease

scientific article published in January 2009

Biomarkers of Coronary Artery Disease Differ Between Asians and Caucasians in the General Population

scientific article published on 07 March 2015

Blocking Interferon β Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis ⬇️

scientific article published on August 24, 2010

Circulating Biomarkers for Predicting Cardiovascular Disease Risk; a Systematic Review and Comprehensive Overview of Meta-Analyses ⬇️

scientific article published on April 22, 2013

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

scientific article published on 07 January 2019

Circulating cells as predictors of secondary manifestations of cardiovascular disease: design of the CIRCULATING CELLS study

scientific article

Circulating endothelial cells in coronary artery disease and acute coronary syndrome

scientific article

Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis

scientific article

Circumferential heterogeneity in the abdominal aortic aneurysm wall composition suggests lateral sides to be more rupture prone ⬇️

scientific article published on September 23, 2011

Cohort profile of BIOMArCS: the BIOMarker study to identify the Acute risk of a Coronary Syndrome-a prospective multicentre biomarker study conducted in the Netherlands

scientific article published on 23 December 2016

Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years

scientific article published on 26 January 2015

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model

scientific article published on 19 October 2015

Differential effects of MCP-1 and leptin on collateral flow and arteriogenesis

scientific article

Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis

scientific article

Effect of Monocyte-to-Lymphocyte Ratio on Heart Failure Characteristics and Hospitalizations in a Coronary Angiography Cohort

scientific article

Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis

scientific article published on 6 March 2009

Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy

scientific article published on 28 September 2008

Ethnicity Modifies Associations between Cardiovascular Risk Factors and Disease Severity in Parallel Dutch and Singapore Coronary Cohorts

scientific article published on 6 July 2015

Evaluation of a novel laser-assisted coronary anastomotic connector - the Trinity Clip - in a porcine off-pump bypass model

scientific article

Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury

scientific article published in February 2009

Experimental models of arteriogenesis: differences and implications

scientific article

Extracellular vesicle protein CD14 relates to common carotid intima-media thickness in eight-year-old children

scientific article published on 28 July 2014

Fractional flow reserve is not associated with inflammatory markers in patients with stable coronary artery disease

scientific article

Gender differences in health-related quality of life in patients undergoing coronary angiography

scientific article

Growth factor therapy in atherosclerotic disease-friend or foe.

scientific article published on January 2007

Haematopoietic and endothelial progenitor cells are deficient in quiescent systemic lupus erythematosus

scientific article

Health-related quality of life and outcome in atherosclerosis - Does sex matter?

scientific article published on 24 March 2016

Hematological Parameters Improve Prediction of Mortality and Secondary Adverse Events in Coronary Angiography Patients: A Longitudinal Cohort Study

scientific article

Hematological Parameters Outperform Plasma Markers in Predicting Long-Term Mortality After Coronary Angiography

scientific article published in January 2017

High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease

scientific article published on 7 September 2017

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

scientific article

Hyaluronic acid: targeting immune modulatory components of the extracellular matrix in atherosclerosis

scientific article published on January 2008

Impaired kidney function is associated with intraplaque hemorrhage in patients undergoing carotid endarterectomy

scientific article published on 22 September 2017

In-vivovalidation of a new non-invasive continuous ventricular stroke volume monitoring system in an animal model ⬇️

scientific article published on July 11, 2011

Increased expression of the transforming growth factor-beta signaling pathway, endoglin, and early growth response-1 in stable plaques

scientific article

Increased platelet reactivity is associated with circulating platelet-monocyte complexes and macrophages in human atherosclerotic plaques

scientific article

Insights into mechanisms behind arteriogenesis: what does the future hold?

scientific article published on 04 August 2008

Inter-Ethnic Differences in Quantified Coronary Artery Disease Severity and All-Cause Mortality among Dutch and Singaporean Percutaneous Coronary Intervention Patients

scientific article published on 6 July 2015

Invasive surgery reduces infarct size and preserves cardiac function in a porcine model of myocardial infarction

scientific article

Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

scientific article published on 16 February 2017

Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

scientific article published on 21 December 2017

Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

scientific article published on 27 January 2014

Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans.

scientific article published in June 2009

Locally applied recombinant plasmin results in effective thrombolysis in a porcine model of arteriovenous graft thrombosis

scientific article published on 28 May 2009

Lower Platelet Reactivity Is Associated with Presentation of Unstable Coronary Artery Disease

scientific article published on 24 October 2016

Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events

scientific article published on 11 June 2013

MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy

scientific article

Monocyte hyporesponsiveness and Toll-like receptor expression profiles in coronary artery bypass grafting and its clinical implications for postoperative inflammatory response and pneumonia: An observational cohort study

scientific article published on March 2015

Myocardial infarction and functional outcome assessment in pigs

scientific article

Past, current and future concepts in atherosclerotic biobanking

scientific article published on November 2008

Pharmaceutical interventions to influence arteriogenesis: new concepts to treat ischemic heart disease

scientific article

Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention

scientific article published in October 2015

Preclinical Testing of Frequency-Tunable Capacitive Micromachined Ultrasonic Transducer Probe Prototypes

scientific article published on 20 June 2017

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

scientific article published on 14 October 2016

Prognostic Value of Circulating Inflammatory Cells in Patients with Stable and Acute Coronary Artery Disease

scientific article published on 14 July 2017

Proteomics of plaques and novel sources of potential biomarkers for atherosclerosis

scientific article published on 09 July 2013

Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events

scientific article

Radiofrequency Ablation of the Atherosclerotic Plaque: a Proof of Concept Study in an Atherosclerotic Model

scientific article

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

scientific article published in November 2007

Reference Values for Cardiac and Aortic Magnetic Resonance Imaging in Healthy, Young Caucasian Adults

scientific article

Relation Between Circulating Inflammatory Chemokines and Vascular Characteristics in Healthy, Young Children

scientific article published on 16 December 2015

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

scientific article published on 26 May 2017

Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease

scientific article published on 13 March 2018

Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

scientific article

Routinely analyzed leukocyte characteristics improve prediction of mortality after coronary angiography

scientific article published on 7 December 2015

Severity of stable coronary artery disease and its biomarkers differ between men and women undergoing angiography

scientific article published on 4 February 2015

Sex, body mass index, and blood pressure are related to aortic characteristics in healthy, young adults using magnetic resonance vessel wall imaging: the AMBITYON study

scientific article published on 31 May 2017

Shear induced collateral artery growth modulated by endoglin but not by ALK1.

scientific article

Six-month healing of the nonocclusive coronary anastomotic connector in an off-pump porcine bypass model

scientific article

Soluble ST2 levels are not associated with secondary cardiovascular events and vulnerable plaque phenotype in patients with carotid artery stenosis

scientific article

Subsequent Event Risk in Individuals With Established Coronary Heart Disease

scientific article published on 21 March 2019

Swarm Intelligence-Enhanced Detection of Non-Small-Cell Lung Cancer Using Tumor-Educated Platelets.

scientific article published in August 2017

Targeted deletion of the inhibitory NF-kappaB p50 subunit in bone marrow-derived cells improves collateral growth after arterial occlusion

scientific article published on 21 May 2010

Targeting adhesion molecules in cardiovascular disorders

scientific article published on December 2008

Targeting danger-associated molecular patterns after myocardial infarction

scientific article published on 30 September 2015

Temporal changes of soluble ST2 after cardiovascular interventions

scientific article published on 6 December 2012

Testosterone to estradiol ratio reflects systemic and plaque inflammation and predicts future cardiovascular events in men with severe atherosclerosis

scientific article published on 01 February 2019

The CD200-CD200 receptor inhibitory axis controls arteriogenesis and local T lymphocyte influx

scientific article

The nonocclusive laser-assisted coronary anastomotic connector in an off-pump porcine bypass model

scientific article

The selective NLRP3-inflammasome inhibitor MCC950 reduces infarct size and preserves cardiac function in a pig model of myocardial infarction

scientific article

Toll-Like Receptor induced CD11b and L-selectin response in patients with coronary artery disease

scientific article

Toll-like receptor 2 and 4 response and expression on monocytes decrease rapidly in patients undergoing arterial surgery and are related to preoperative smoking

scientific article published in January 2009

Toll-like receptor 4 is involved in human and mouse vein graft remodeling, and local gene silencing reduces vein graft disease in hypercholesterolemic APOE*3Leiden mice

scientific article published on 17 February 2011

Total Arterial Minimally Invasive Direct Coronary Artery Bypass Surgery Facilitated by the Trinity Clip Connector

scientific article published on 16 December 2015

Transendocardial cell injection is not superior to intracoronary infusion in a porcine model of ischaemic cardiomyopathy: a study on delivery efficiency

scientific article

Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models

scientific article

Uniform data collection in routine clinical practice in cardiovascular patients for optimal care, quality control and research: The Utrecht Cardiovascular Cohort

scientific article

Women Undergoing Coronary Angiography for Myocardial Infarction or Who Present With Multivessel Disease Have a Poorer Prognosis Than Men.

scientific article published on 07 September 2015

Xenotransplantation of Human Cardiomyocyte Progenitor Cells Does Not Improve Cardiac Function in a Porcine Model of Chronic Ischemic Heart Failure. Results from a Randomized, Blinded, Placebo Controlled Trial

scientific article

List of works by Imo Hoefer

3D black blood VISTA vessel wall cardiovascular magnetic resonance of the thoracic aorta wall in young, healthy adults: reproducibility and implications for efficacy trial sample sizes: a cross-sectional study

A fibronectin‐fibrinogen‐tropoelastin coating reduces smooth muscle cell growth but improves endothelial cell function ⬇️

A membrane-based microfluidic device for mechano-chemical cell manipulation

A new intra-arterial delivery platform for pro-arteriogenic compounds to stimulate collateral artery growth via transforming growth factor-beta1 release

A single preoperative blood test predicts postoperative sepsis and pneumonia after coronary bypass or open aneurysm surgery

Additional Candidate Genes for Human Atherosclerotic Disease Identified Through Annotation Based on Chromatin Organization

Admittance-based pressure-volume loops versus gold standard cardiac magnetic resonance imaging in a porcine model of myocardial infarction

Arteriogenesis proceeds via ICAM-1/Mac-1- mediated mechanisms

Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion

Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Beyond the matrix: MMP2 as critical regulator of inflammation-mediated vascular dysfunction

Biobanks and the search for predictive biomarkers of local and systemic outcome in atherosclerotic disease

Biomarkers of Coronary Artery Disease Differ Between Asians and Caucasians in the General Population

Blocking Interferon β Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis ⬇️

Circulating Biomarkers for Predicting Cardiovascular Disease Risk; a Systematic Review and Comprehensive Overview of Meta-Analyses ⬇️

Circulating CD14+CD16- classical monocytes do not associate with a vulnerable plaque phenotype, and do not predict secondary events in severe atherosclerotic patients

Circulating cells as predictors of secondary manifestations of cardiovascular disease: design of the CIRCULATING CELLS study

Circulating endothelial cells in coronary artery disease and acute coronary syndrome

Circulating immunoglobulins are not associated with intraplaque mast cell number and other vulnerable plaque characteristics in patients with carotid artery stenosis

Circumferential heterogeneity in the abdominal aortic aneurysm wall composition suggests lateral sides to be more rupture prone ⬇️

Cohort profile of BIOMArCS: the BIOMarker study to identify the Acute risk of a Coronary Syndrome-a prospective multicentre biomarker study conducted in the Netherlands

Common carotid intima-media thickness relates to cardiovascular events in adults aged <45 years

Development and evaluation of in vivo tissue engineered blood vessels in a porcine model

Differential effects of MCP-1 and leptin on collateral flow and arteriogenesis

Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis

Effect of Monocyte-to-Lymphocyte Ratio on Heart Failure Characteristics and Hospitalizations in a Coronary Angiography Cohort

Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis

Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy

Ethnicity Modifies Associations between Cardiovascular Risk Factors and Disease Severity in Parallel Dutch and Singapore Coronary Cohorts

Evaluation of a novel laser-assisted coronary anastomotic connector - the Trinity Clip - in a porcine off-pump bypass model

Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury

Experimental models of arteriogenesis: differences and implications

Extracellular vesicle protein CD14 relates to common carotid intima-media thickness in eight-year-old children

Fractional flow reserve is not associated with inflammatory markers in patients with stable coronary artery disease

Gender differences in health-related quality of life in patients undergoing coronary angiography

Growth factor therapy in atherosclerotic disease-friend or foe.

Haematopoietic and endothelial progenitor cells are deficient in quiescent systemic lupus erythematosus

Health-related quality of life and outcome in atherosclerosis - Does sex matter?

Hematological Parameters Improve Prediction of Mortality and Secondary Adverse Events in Coronary Angiography Patients: A Longitudinal Cohort Study

Hematological Parameters Outperform Plasma Markers in Predicting Long-Term Mortality After Coronary Angiography

High Levels of (Un)Switched Memory B Cells Are Associated With Better Outcome in Patients With Advanced Atherosclerotic Disease

Human Validation of Genes Associated With a Murine Atherosclerotic Phenotype

Hyaluronic acid: targeting immune modulatory components of the extracellular matrix in atherosclerosis

Impaired kidney function is associated with intraplaque hemorrhage in patients undergoing carotid endarterectomy

In-vivovalidation of a new non-invasive continuous ventricular stroke volume monitoring system in an animal model ⬇️

Increased expression of the transforming growth factor-beta signaling pathway, endoglin, and early growth response-1 in stable plaques

Increased platelet reactivity is associated with circulating platelet-monocyte complexes and macrophages in human atherosclerotic plaques

Insights into mechanisms behind arteriogenesis: what does the future hold?

Inter-Ethnic Differences in Quantified Coronary Artery Disease Severity and All-Cause Mortality among Dutch and Singaporean Percutaneous Coronary Intervention Patients

Invasive surgery reduces infarct size and preserves cardiac function in a porcine model of myocardial infarction

Leukocyte TLR5 deficiency inhibits atherosclerosis by reduced macrophage recruitment and defective T-cell responsiveness

Leukocyte-Associated Immunoglobulin-like Receptor-1 is regulated in human myocardial infarction but its absence does not affect infarct size in mice

Leukotriene B4 levels in human atherosclerotic plaques and abdominal aortic aneurysms

Local cytokine concentrations and oxygen pressure are related to maturation of the collateral circulation in humans.

Locally applied recombinant plasmin results in effective thrombolysis in a porcine model of arteriovenous graft thrombosis

Lower Platelet Reactivity Is Associated with Presentation of Unstable Coronary Artery Disease

Mast cells in human carotid atherosclerotic plaques are associated with intraplaque microvessel density and the occurrence of future cardiovascular events

MicroRNA-100 Suppresses Chronic Vascular Inflammation by Stimulation of Endothelial Autophagy

Monocyte hyporesponsiveness and Toll-like receptor expression profiles in coronary artery bypass grafting and its clinical implications for postoperative inflammatory response and pneumonia: An observational cohort study

Myocardial infarction and functional outcome assessment in pigs

Past, current and future concepts in atherosclerotic biobanking

Pharmaceutical interventions to influence arteriogenesis: new concepts to treat ischemic heart disease

Platelet density per monocyte predicts adverse events in patients after percutaneous coronary intervention

Preclinical Testing of Frequency-Tunable Capacitive Micromachined Ultrasonic Transducer Probe Prototypes

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Prognostic Value of Circulating Inflammatory Cells in Patients with Stable and Acute Coronary Artery Disease

Proteomics of plaques and novel sources of potential biomarkers for atherosclerosis

Race/Ethnic Differences in the Associations of the Framingham Risk Factors with Carotid IMT and Cardiovascular Events

Radiofrequency Ablation of the Atherosclerotic Plaque: a Proof of Concept Study in an Atherosclerotic Model

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

Reference Values for Cardiac and Aortic Magnetic Resonance Imaging in Healthy, Young Caucasian Adults

Relation Between Circulating Inflammatory Chemokines and Vascular Characteristics in Healthy, Young Children

Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

Renin and aldosterone are not associated with vulnerable plaque characteristics in patients with carotid artery disease

Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".

Routinely analyzed leukocyte characteristics improve prediction of mortality after coronary angiography

Severity of stable coronary artery disease and its biomarkers differ between men and women undergoing angiography

Sex, body mass index, and blood pressure are related to aortic characteristics in healthy, young adults using magnetic resonance vessel wall imaging: the AMBITYON study