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List of works by Sergio Fucile

About a new method to measure fractional Ca2+ currents through ligand-gated ion channels

scientific article published on September 2009

Activation of the nicotinic acetylcholine receptor mobilizes calcium from caffeine-insensitive stores in C2C12 mouse myotubes.

scientific article published on March 1993

Acute and chronic effects of hypercalcaemia on cortical excitability as studied by 5 Hz repetitive transcranial magnetic stimulation

Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.

scholarly article

Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization

scientific article published on 20 June 2015

CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.

scientific article published on February 2013

Ca2+ permeability of mouse and chick nicotinic acetylcholine receptors expressed in transiently transfected human cells ⬇️

scientific article published on March 15, 1998

Ca2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neurones

scientific journal article

Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists

scientific article published on 30 July 2015

Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.

scientific article published in August 2002

Cholinergic stimulation of human microcytoma cell line H69.

scientific article published on January 1997

Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor.

scientific article published on June 1999

Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neurons

scientific article published on 24 April 2015

Cyclin D1 degradation enhances endothelial cell survival upon oxidative stress

scientific article published in June 2006

Cysteine residues are critical for chemokine receptor CXCR2 functional properties

scientific article

Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors

scientific article

Electrophysiological properties of mouse bone marrow c-kit+ cells co-cultured onto neonatal cardiac myocytes.

scientific article published in June 2005

Enhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy.

scientific article

Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors.

scientific article

Extracellular mild acidosis decreases the Ca2+ permeability of the human NMDA receptors

scientific article published on 04 April 2019

FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.

scientific article published on 2 December 2013

Fast potentiation of glycine receptor channels of intracellular calcium in neurons and transfected cells

scientific article published on 01 November 2000

Fluoxetine prevents acetylcholine-induced excitotoxicity blocking human endplate acetylcholine receptor

scientific article published on 15 July 2013

Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy

scientific article published on 13 September 2013

From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor.

scientific article published on 21 October 2016

Functional properties of cells obtained from human cord blood CD34+ stem cells and mouse cardiac myocytes in coculture.

scientific article published on 25 January 2008

Functional properties of neuronal nicotinic acetylcholine receptor channels expressed in transfected human cells.

scientific article

Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo

scientific article published in June 2006

Genetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis

scientific article

Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.

scientific article

Human iPSC Modeling of Genetic Febrile Seizure Reveals Aberrant Molecular and Physiological Features Underlying an Impaired Neuronal Activity

scientific article published on 05 May 2022

Identification of a determinant of acetylcholine receptor gating kinetics in the extracellular portion of the gamma subunit.

scientific article published on December 1996

Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes

scientific article

LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism

scientific article

Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex

scientific article

Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.

scientific article published in June 2010

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

scientific article

Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel.

scientific article published on 5 April 2011

New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors

scientific article

Nicotinic cholinergic stimulation promotes survival and reduces motility of cultured rat cerebellar granule cells.

scientific article

PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanism

scientific article published on 27 October 2011

Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis

scientific article

Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation.

scientific article published in January 2002

Spontaneous and evoked oscillations of cytosolic calcium in the freshly prepared ciliary epithelial bilayer of the rabbit eye

scientific article published on 01 March 1996

The Distribution of Charged Amino Acid Residues and the Ca2+ Permeability of Nicotinic Acetylcholine Receptors: A Predictive Model.

scientific article published on 29 May 2017

The neuronal α6 subunit forms functional heteromeric acetylcholine receptors in human transfected cells ⬇️

scientific article published on January 1, 1998

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