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List of works by Cinzia Rinaldo

An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis

scientific article published on 20 February 2020

CDKL5 localizes at the centrosome and midbody and is required for faithful cell division

scientific article published on 24 July 2017

Co-targeting of Bcl-2 and mTOR pathway triggers synergistic apoptosis in BH3 mimetics resistant acute lymphoblastic leukemia

scientific article published on 16 September 2015

Effects of Y361-auto-phosphorylation on structural plasticity of the HIPK2 kinase domain

scientific article

Extrachromosomal Histone H2B Contributes to the Formation of the Abscission Site for Cell Division

scientific article published on 05 November 2019

Gal-3 is stimulated by gain-of-function p53 mutations and modulates chemoresistance in anaplastic thyroid carcinomas.

scientific article

HIPK2 and extrachromosomal histone H2B are separately recruited by Aurora-B for cytokinesis.

scientific article published on 22 March 2018

HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity

scientific article published in April 2015

HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage.

scientific article

HIPK2 phosphorylates ΔNp63α and promotes its degradation in response to DNA damage.

scientific article

HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation

scientific article

HIPK2: a multitalented partner for transcription factors in DNA damage response and development.

scientific article

HIPKs: Jack of all trades in basic nuclear activities.

scientific article published on 18 June 2008

High Mobility Group A1 (HMGA1) proteins interact with p53 and inhibit its apoptotic activity.

scientific article published on 9 December 2005

High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2.

scientific article published on 8 February 2007

Hmga1 null mouse embryonic fibroblasts display downregulation of spindle assembly checkpoint gene expression associated to nuclear and karyotypic abnormalities

scientific article published on 18 February 2016

Homeodomain-interacting Protein Kinase-2 Stabilizes p27kip1 by Its Phosphorylation at Serine 10 and Contributes to Cell Motility ⬇️

scientific article published on June 29, 2011

Homeodomain-interacting protein kinase-2 stabilizes p27kip1 by its phosphorylation at serine 10 and contributes to cell motility.

scientific article

MDM2-regulated degradation of HIPK2 prevents p53Ser46 phosphorylation and DNA damage-induced apoptosis.

scientific article

MDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic pathway

scientific article

MYCN sensitizes human neuroblastoma to apoptosis by HIPK2 activation through a DNA damage response.

scientific article published on 20 December 2010

Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.

scientific article published on June 2006

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

scientific article published on 11 September 2009

Spastin recovery in hereditary spastic paraplegia by preventing neddylation-dependent degradation

scientific article published on 26 October 2020

The Loss of the p53 Activator HIPK2 Is Responsible for Galectin-3 Overexpression in Well Differentiated Thyroid Carcinomas ⬇️

scientific article published on June 17, 2011

Therapeutic targeting of Chk1 in NSCLC stem cells during chemotherapy.

scientific article published on 25 November 2011

Updates on HIPK2: a resourceful oncosuppressor for clearing cancer ⬇️

scientific article published on August 13, 2012

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