List of works - Scott E Boyken

A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase

scientific article

Accurate computational design of multipass transmembrane proteins.

scientific article published in March 2018

An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition.

scientific article published on 18 May 2017

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds

scientific article published on 18 March 2020

Computational design of transmembrane pores

scientific article published on 26 August 2020

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport ⬇️

scientific article published on September 23, 2010

De novo design of a homo-trimeric amantadine-binding protein

scientific article published on 19 December 2019

De novo design of modular and tunable protein biosensors

scientific article published on 27 January 2021

De novo design of protein logic gates

scientific article published on 01 April 2020

De novo design of tunable, pH-driven conformational changes.

scientific article published on 01 May 2019

Designed protein logic to target cells with precise combinations of surface antigens

scientific article published on 20 August 2020

Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

scientific article

Macromolecular modeling and design in Rosetta: recent methods and frameworks

scientific article published on 01 June 2020

Modeling oblong proteins and water-mediated interfaces with RosettaDock in CAPRI rounds 28-35.

scientific article published on 26 September 2016

Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain

scientific article

Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design

scientific article published on 20 April 2018

Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec.

scientific article

The coming of age of de novo protein design

scientific article published on 14 September 2016

List of works by Scott E Boyken

A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase

Accurate computational design of multipass transmembrane proteins.

An Autoinhibitory Role for the Pleckstrin Homology Domain of Interleukin-2-Inducible Tyrosine Kinase and Its Interplay with Canonical Phospholipid Recognition.

Computational design of closely related proteins that adopt two well-defined but structurally divergent folds

Computational design of transmembrane pores

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport ⬇️

De novo design of a homo-trimeric amantadine-binding protein

De novo design of modular and tunable protein biosensors

De novo design of protein logic gates

De novo design of tunable, pH-driven conformational changes.

Designed protein logic to target cells with precise combinations of surface antigens

Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases

Macromolecular modeling and design in Rosetta: recent methods and frameworks

Modeling oblong proteins and water-mediated interfaces with RosettaDock in CAPRI rounds 28-35.

Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain

Rapid Sampling of Hydrogen Bond Networks for Computational Protein Design

Rescue of the aggregation prone Itk Pleckstrin Homology domain by two mutations derived from the related kinases, Btk and Tec.

The coming of age of de novo protein design