List of works - Patrick Ernst

Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.

scientific article published on 31 January 2018

Advances in the design and engineering of peptide-binding repeat proteins

scientific article published on 16 September 2016

An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture

article by Mohammad ElGamacy et al published 27 August 2018 in ACS Synthetic Biology

Anti-SSTR2 antibody-drug conjugate for neuroendocrine tumor therapy

scientific article published on 20 July 2020

Chaperone-assisted structure elucidation with DARPins

scientific article published on 06 January 2020

Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition

scientific article

Curvature of designed armadillo repeat proteins allows modular peptide binding

scientific article published on 29 August 2017

Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity.

scientific article published on 24 November 2017

Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization

scientific article published on 18 November 2021

Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action

scientific article published on 18 June 2021

Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

scientific article

MitoQ regulates redox-related noncoding RNAs to preserve mitochondrial network integrity in pressure-overload heart failure

scientific article published on 31 January 2020

Mitochondrial-Mediated Oxidative Ca/Calmodulin-Dependent Kinase II Activation Induces Early Afterdepolarizations in Guinea Pig Cardiomyocytes: An In Silico Study

Precisely Control Mitochondria with Light to Manipulate Cell Fate Decision

scientific article published on 26 July 2019

Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins

scientific article published on 01 October 2019

Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts

scientific article published on 07 November 2019

Structural analysis of biological targets by host:guest crystal lattice engineering

scientific article published on 23 October 2019

Structure-Guided Design of a Peptide Lock for Modular Peptide Binders

scientific article published on 13 February 2020

List of works by Patrick Ernst