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List of works by Alain Tedgui

2011 Nobel Prize in Physiology or Medicine: Toll-like receptors, dendritic cells, and their roles in atherosclerosis

scientific article

A CD31-derived peptide prevents angiotensin II-induced atherosclerosis progression and aneurysm formation

scientific article published on 31 January 2012

Acute impact of apheresis on oxidized phospholipids in patients with familial hypercholesterolemia

scientific article published on 24 May 2012

Adaptive (T and B cells) immunity and control by dendritic cells in atherosclerosis

scientific article published on May 2014

Adaptive T Cell Immunity

Adaptive T cell immune responses and atherogenesis

scientific article published on 05 March 2010

Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets

scientific article published on 19 April 2011

Age and gender effects on apoptosis in the human coronary arterial wall

Age-related phenotypes in the staggerer mouse expand the RORalpha nuclear receptor's role beyond the cerebellum

scientific article

Alain Tedgui: atherosclerosis research à la Française

scientific article published in December 2014

Angiotensin II mobilizes spleen monocytes to promote the development of abdominal aortic aneurysm in Apoe-/- mice

scientific article published on 18 December 2014

Angiotensin II synergizes with BAFF to promote atheroprotective regulatory B cells

scientific article

Apoptose et syndromes coronariens aigus

Apoptotic cell death and efferocytosis in atherosclerosis

scientific article published on 09 February 2012

Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study

scientific article

B cell depletion reduces the development of atherosclerosis in mice

scientific article

B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction

scientific article

Bone marrow transplantation reveals the in vivo expression of the mitochondrial uncoupling protein 2 in immune and nonimmune cells during inflammation

scientific article

CD40 ligand+ microparticles from human atherosclerotic plaques stimulate endothelial proliferation and angiogenesis a potential mechanism for intraplaque neovascularization

scientific article

Cardiovascular Research in France.

scientific article

Cellular Origins and Thrombogenic Activity of Microparticles Isolated From Human Atherosclerotic Plaques

article

Cellular mechanics and gene expression in blood vessels ⬇️

scientific article published on May 1, 2003

Chemokine receptor CCR1 disruption in bone marrow cells enhances atherosclerotic lesion development and inflammation in mice

scientific article

Circulating endothelial microparticles are associated with vascular dysfunction in patients with end-stage renal failure

scientific article

Circulating levels of interleukin-17 and cardiovascular outcomes in patients with acute myocardial infarction

scholarly article by Tabassome Simon et al published 6 September 2012 in European Heart Journal

Circulating levels of secretory- and lipoprotein-associated phospholipase A2 activities: relation to atherosclerotic plaques and future all-cause mortality

scientific article published on 17 June 2012

Circulating microparticles and procoagulant activity in elderly patients

scientific article

Circulating microparticles: a potential prognostic marker for atherosclerotic vascular disease

scientific article published on 26 June 2006

Circulating procoagulant microparticles in acute pulmonary embolism: A case–control study

Circulating secretory phospholipase A2 activity and risk of incident coronary events in healthy men and women: the EPIC-Norfolk study

scientific article published on 15 February 2007

Circulating secretory phospholipase A2 activity predicts recurrent events in patients with severe acute coronary syndromes

scientific article

Combined Inhibition of CCL2, CX3CR1, and CCR5 Abrogates Ly6C hi and Ly6C lo Monocytosis and Almost Abolishes Atherosclerosis in Hypercholesterolemic Mice

article by Christophe Combadière et al published April 2008 in Circulation

Cytokine network and T cell immunity in atherosclerosis

scientific article published on 02 April 2009

Cytokines and Atherosclerosis

Cytokines as regulators of atherosclerosis in murine models

scientific article published on December 2007

Cytokines in atherosclerosis: pathogenic and regulatory pathways

scientific article

Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice

scientific article published in February 2003

Defective leptin/leptin receptor signaling improves regulatory T cell immune response and protects mice from atherosclerosis

scientific article

Defective mer receptor tyrosine kinase signaling in bone marrow cells promotes apoptotic cell accumulation and accelerates atherosclerosis

scientific article published on 8 May 2008

Differential regulation of vascular focal adhesion kinase by steady stretch and pulsatility

scientific article published on 24 January 2005

Dying for attention: microparticles and angiogenesis

scientific article published in July 2005

Effects of rosuvastatin and atorvastatin on the apolipoprotein B/apolipoprotein A-1 ratio in patients with an acute coronary syndrome: The CENTAURUS trial design

scientific article published in June 2008

Endothelial autophagic flux hampers atherosclerotic lesion development

scientific article published on 20 November 2017

Endothelial microparticles in diseases

scientific article

Erythrocyte microparticles can induce kidney vaso-occlusions in a murine model of sickle cell disease

scientific article published on 13 September 2012

Evidence for altered interleukin 18 (IL)-18 pathway in human heart failure.

scientific article

Evidence of Apoptosis in Arrhythmogenic Right Ventricular Dysplasia

article

Evidence of a role for lactadherin in Alzheimer's disease

scientific article published on March 2007

Factors influencing the level of circulating procoagulant microparticles in acute pulmonary embolism

Feeding sugar to tumors: with a supplement of miR?

scientific article published on 19 December 2012

French Intensive Care Society, International congress - Réanimation 2016

scientific article published in June 2016

Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency

scientific article published on 14 November 2011

Genetic Depletion or Hyperresponsiveness of Natural Killer Cells Do Not Affect Atherosclerosis Development

scientific article

Genetic and Pharmacological Inhibition of TREM-1 Limits the Development of Experimental Atherosclerosis

scientific article published in December 2016

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

scientific article published on 28 November 2017

Gingival fibroblasts protect against experimental abdominal aortic aneurysm development and rupture through tissue inhibitor of metalloproteinase-1 production

scientific article published on 5 June 2017

HDL, PTX3, and vascular protection

scientific article published in May 2008

Humoral and cellular immune responses in atherosclerosis: spotlight on B- and T-cells

scientific article published on 08 February 2012

Hypertension: A Novel Regulator of Adaptive Immunity in Atherosclerosis?

IAP survivin regulates atherosclerotic macrophage survival

scientific article published on 25 January 2007

IL-17 and Th17 cells in atherosclerosis: subtle and contextual roles

scientific article

IL-17 in atherosclerosis: the good and the bad.

scientific article published on 8 December 2017

Immunomodulation to combat atherosclerosis: the potential role of immune regulatory cells

scientific article published in September 2004

Impairment in postischemic neovascularization in mice lacking the CXC chemokine receptor 3.

scientific article published on 17 February 2005

In Vivo Shear Stress Determines Circulating Levels of Endothelial Microparticles in End-Stage Renal Disease

In vivo characterization of a new abdominal aortic aneurysm mouse model with conventional and molecular magnetic resonance imaging

scientific article published on December 2011

Increased vitreous shedding of microparticles in proliferative diabetic retinopathy stimulates endothelial proliferation

scientific article published on 15 December 2009

Indoleamine 2 3-dioxygenase knockout limits angiotensin II-induced aneurysm in low density lipoprotein receptor-deficient mice fed with high fat diet

scientific article published in March 2018

Indoleamine 2,3-Dioxygenase Fine-Tunes Immune Homeostasis in Atherosclerosis and Colitis through Repression of Interleukin-10 Production.

scientific article

Induction of a regulatory T cell type 1 response reduces the development of atherosclerosis in apolipoprotein E-knockout mice

scientific article published on 11 August 2003

Infection duration and inflammatory imbalance are associated with atherosclerotic risk in HIV-infected never-smokers independent of antiretroviral therapy

scientific article

Inhibition of microRNA-92a prevents endothelial dysfunction and atherosclerosis in mice

scientific journal article

Innate lymphoid cells: new players in atherosclerosis?

scientific article

Interleukin-17: friend or foe in atherosclerosis?

scientific article published on October 2010

Interleukin-18/interleukin-18 binding protein signaling modulates ischemia-induced neovascularization in mice hindlimb

scientific article

La lactadhérine, nouvel acteur de l’angiogenèse

Lactadherin deficiency leads to apoptotic cell accumulation and accelerated atherosclerosis in mice

scientific article published on 9 April 2007

Lactadherin promotes VEGF-dependent neovascularization

scientific article (publication date: May 2005)

Leukocyte-derived interleukin 10 is required for protection against atherosclerosis in low-density lipoprotein receptor knockout mice

scientific article published on 3 June 2004

Levels of Circulating Procoagulant Microparticles in Nonvalvular Atrial Fibrillation

article published in 2007

Lipoprotein-associated and secreted phospholipases A₂ in cardiovascular disease: roles as biological effectors and biomarkers.

scientific article

Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression

scientific article published on 03 September 2015

Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosis

scientific article published on 08 September 2009

Lp-PLA2 et sPLA2

MFGE8 inhibits inflammasome-induced IL-1β production and limits postischemic cerebral injury

scientific article published on February 2013

Measles virus nucleoprotein induces a regulatory immune response and reduces atherosclerosis in mice

scientific article published on 17 September 2007

Mechanisms of blood flow-induced vascular enlargement.

scientific article

Mechanosensitive PPAP2B Regulates Endothelial Responses to Atherorelevant Hemodynamic Forces

scientific article

Mediators of Vascular Inflammation

MicroRNAs as therapeutic targets in atherosclerosis

scientific article

Microparticles from ischemic muscle promotes postnatal vasculogenesis.

scientific article

Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1

scientific article

Microparticles: key protagonists in cardiovascular disorders

scientific article

Microvesicles as cell-cell messengers in cardiovascular diseases

scientific article published on January 2014

Monocytes, Macrophages and Other Inflammatory Mediators of Abdominal Aortic Aneurysm

scientific article published on 25 August 2015

Natural regulatory T cells control the development of atherosclerosis in mice

article

Natural regulatory T cells limit angiotensin II-induced aneurysm formation and rupture in mice

scientific article published in August 2013

Overexpression of SOCS3 in T lymphocytes leads to impaired interleukin-17 production and severe aortic aneurysm formation in mice--brief report

scientific article published on 17 January 2013

Oxidation-specific biomarkers, lipoprotein(a), and risk of fatal and nonfatal coronary events

scientific article published on September 2010

Periodontal microbiota and phospholipases: the Oral Infections and Vascular Disease Epidemiology Study (INVEST).

scientific article published on 22 July 2015

Phospholipase A2 enzymes, high-dose atorvastatin, and prediction of ischemic events after acute coronary syndromes

scientific article published on 9 January 2012

Platelets in atherosclerosis: a new role for beta-amyloid peptide beyond Alzheimer's disease.

scientific article

Post-ischaemic neovascularization and inflammation

scientific article published on 05 February 2008

Predischarge C-Reactive Protein and 1-year Outcome After Acute Coronary Syndromes

Pressure-induced matrix metalloproteinase-9 contributes to early hypertensive remodeling

scientific article published on 16 February 2004

Prognostic utility of secretory phospholipase A(2) in patients with stable coronary artery disease

scientific article published on 22 July 2011

Proteomics, metabolomics, and immunomics on microparticles derived from human atherosclerotic plaques

scientific article

Recent advances on the role of cytokines in atherosclerosis

scientific article published on May 2011

Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice

scientific article published on 10 October 2002

Regulatory T cell responses: potential role in the control of atherosclerosis

scientific article

Regulatory T-Cell Plasticity: Another Layer of Complexity in Atherosclerosis.

scientific article

Regulatory T-Cell Response to Apolipoprotein B100–Derived Peptides Reduces the Development and Progression of Atherosclerosis in Mice

article

Regulatory T-cell immunity in atherosclerosis

scientific article published on May 2007

Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results from the EPIC-Norfolk Study

scientific article

Retinol-binding protein 4 and prediction of incident coronary events in healthy men and women

scientific article

Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice

scientific article published on 2 October 2003

Role of Bone Marrow–Derived CC-Chemokine Receptor 5 in the Development of Atherosclerosis of Low-Density Lipoprotein Receptor Knockout Mice

article

Role of Microvascular Tone and Extracellular Matrix Contraction in the Regulation of Interstitial Fluid: Implications for Aortic Dissection

scientific article

Role of NF-kappaB in flow-induced vascular remodeling

scientific article published in July 2009

Rôle du TGFβ dans un modèle d’anévrisme de l’aorte abdominale chez la souris

Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study

scientific article published on 31 July 2013

Selective EGF-Receptor Inhibition in CD4+ T Cells Induces Anergy and Limits Atherosclerosis

scientific article

Selective EGFR (Epidermal Growth Factor Receptor) Deletion in Myeloid Cells Limits Atherosclerosis-Brief Report

scientific article published on 30 November 2017

Serum secreted phospholipase A2 is associated with abdominal aortic aneurysm presence but not progression

Shear stress regulates endothelial microparticle release.

scientific article published on 27 March 2013

Smooth muscle dysfunction in resistance arteries of the staggerer mouse, a mutant of the nuclear receptor RORalpha

scientific article published in April 2002

Specific abrogation of transforming growth factor-beta signaling in T cells alters atherosclerotic lesion size and composition in mice

scientific article published on 14 August 2003

TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice

scientific article published on 25 January 2010

The "CholesteROR" protective pathway in the vascular system

scientific article published on 29 January 2004

The Dendritic Cell Receptor DNGR-1 Promotes the Development of Atherosclerosis in Mice

scientific article published on 12 June 2017

The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections: A Mirage?

scientific article

The estrogen effects on endothelial repair and mitogen-activated protein kinase activation are abolished in endothelial nitric-oxide (NO) synthase knockout mice, but not by NO synthase inhibition by N-nitro-L-arginine methyl ester

scientific article

The intravenous injection of oxidized LDL- or Apolipoprotein B100 – Coupled splenocytes promotes Th1 polarization in wildtype and Apolipoprotein E – Deficient mice

scholarly article by Martin Steinmetz published in August 2015

The role of adaptive T cell immunity in atherosclerosis

scientific article published on 02 December 2008

The role of transforming growth factor beta in atherosclerosis: novel insights and future perspectives

scientific article

Transplantation of bone marrow-derived mononuclear cells in ischemic apolipoprotein E-knockout mice accelerates atherosclerosis without altering plaque composition

scientific article

p47phox-dependent NADPH oxidase regulates flow-induced vascular remodeling

scientific article published on 18 August 2005

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