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List of works by David J Topham

A Live Attenuated Influenza Vaccine Elicits Enhanced Heterologous Protection When the Internal Genes of the Vaccine Are Matched to Those of the Challenge Virus

scientific article published on 31 January 2020

A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation.

scientific article published on 27 September 2017

A systems genomics approach uncovers molecular associates of RSV severity

scientific article published on 28 December 2021

Aims, Study Design, and Enrollment Results From the Assessing Predictors of Infant Respiratory Syncytial Virus Effects and Severity Study

scientific article published on 06 June 2019

Androgen receptor signaling in the lungs mitigates inflammation and improves the outcome of influenza in mice

scientific article published on 09 July 2020

Avian flu: Gain-of-function experiments on H7N9.

scientific article published in August 2013

Both Neutralizing and Non-Neutralizing Human H7N9 Influenza Vaccine-Induced Monoclonal Antibodies Confer Protection

scientific article published on June 2016

Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus

scientific article published on 03 April 2019

Broad cross-reactive IgG responses elicited by adjuvanted vaccination with recombinant influenza hemagglutinin (rHA) in ferrets and mice.

scientific article published on 11 April 2018

CD4 T Cell Epitope Specificity and Cytokine Potential Are Preserved as Cells Transition from the Lung Vasculature to Lung Tissue following Influenza Virus Infection

scholarly article by Anthony DiPiazza et al published 1 July 2018 in Journal of Virology

COVID-19 and human milk: SARS-CoV-2, antibodies, and neutralizing capacity

scientific article published on 18 September 2020

Characterizing Emerging Canine H3 Influenza Viruses

scientific article published on 14 April 2020

Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines

scientific article published on 10 October 2019

Discordant rearrangement of primary and anamnestic CD8+ T cell responses to influenza A viral epitopes upon exposure to bacterial superantigens: Implications for prophylactic vaccination, heterosubtypic immunity and superinfections

scientific article published on 20 May 2020

Formation and Maintenance of Tissue Resident Memory CD8+ T Cells after Viral Infection

scientific article published on 18 October 2019

Functional Evolution of Influenza Virus NS1 Protein in Currently Circulating Human 2009 Pandemic H1N1 Viruses.

scientific article published on 21 June 2017

Functional Evolution of the 2009 Pandemic H1N1 Influenza Virus NS1 and PA in Humans

scholarly article by Aitor Nogales published in October 2018

Gain-of-function experiments on H7N9.

scientific article published in August 2013

Heterovariant cross-reactive B-cell responses induced by the 2009 pandemic influenza virus A subtype H1N1 vaccine

scientific article

In situ neutrophil efferocytosis shapes T cell immunity to influenza infection

scientific article published on 03 August 2020

Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication

scientific article published on 27 August 2019

Interplay of PA-X and NS1 Proteins in Replication and Pathogenesis of a Temperature-Sensitive 2009 Pandemic H1N1 Influenza A Virus

scientific article published on 21 June 2017

Live Imaging of Influenza Infection of the Trachea Reveals Dynamic Regulation of CD8+ T Cell Motility by Antigen

scientific article (publication date: September 2016)

Live attenuated H7N7 influenza vaccine primes for a vigorous antibody response to inactivated H7N7 influenza vaccine.

scientific article

Middle-aged individuals may be in a perpetual state of H3N2 influenza virus susceptibility

scientific article published on 11 September 2020

Modulation of Innate Immune Responses by the Influenza A NS1 and PA-X Proteins

article

Monoclonal Antibody Responses after Recombinant Hemagglutinin Vaccine versus Subunit Inactivated Influenza Virus Vaccine: a Comparative Study

scientific article published on 15 October 2019

NS1 Protein Amino Acid Changes D189N and V194I Affect Interferon Responses, Thermosensitivity, and Virulence of Circulating H3N2 Human Influenza A Viruses

scientific article published on 21 December 2016

NS1 Protein Mutation I64T Affects Interferon Responses and Virulence of Circulating H3N2 Human Influenza A Viruses.

scientific article published on 17 August 2016

Novel Functions of IFI44L as a Feedback Regulator of Host Antiviral Responses

scientific article published on 15 October 2019

Protection against lethal influenza with a viral mimic

scientific article published on 29 May 2013

Recombinant HA-based vaccine outperforms split and subunit vaccines in elicitation of influenza-specific CD4 T cells and CD4 T cell-dependent antibody responses in humans

scientific article published on 26 August 2020

Role of Memory B Cells in Hemagglutinin-Specific Antibody Production Following Human Influenza A Virus Infection

scientific article published on 28 September 2019

S Protein-Reactive IgG and Memory B Cell Production after Human SARS-CoV-2 Infection Includes Broad Reactivity to the S2 Subunit

scientific article published on 25 September 2020

Short term results of vaccination with adjuvanted recombinant varicella zoster glycoprotein E during initial BTK inhibitor therapy for CLL or lymphoplasmacytic lymphoma

scientific article published on 30 October 2020

T cell and chemokine receptors differentially control CD8 T cell motility behavior in the infected airways immediately before and after virus clearance in a primary infection

scientific article published on 20 August 2020

TRM integrins CD103 and CD49a differentially support adherence and motility after resolution of influenza virus infection

scientific article published on 21 May 2020

Temperature-Sensitive Live-Attenuated Canine Influenza Virus H3N8 Vaccine

scientific article published on 07 December 2016

The K186E Amino Acid Substitution in the Canine Influenza Virus H3N8 NS1 Protein Restores Its Ability To Inhibit Host Gene Expression.

scientific article

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