List of works - Peter A Crawford

Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity.

scientific article published on 20 August 2010

Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling.

scientific article

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond

scientific article published on 14 July 2017

Comprehensive and Quantitative Analysis of Polyphosphoinositide Species by Shotgun Lipidomics Revealed Their Alterations in db/db Mouse Brain.

scientific article

Coordinated regulation of the metabolome and lipidome at the host-microbial interface

scientific article

DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function

scientific journal article

Developmental and Physiologic Roles of the Nuclear Receptor Steroidogenic Factor-1 in the Reproductive System

scientific article published on January 1, 1998

Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

scientific article

Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.

scientific article published on 20 May 2013

Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice

scientific article

Intra- and inter-subject variability for increases in serum ketone bodies in patients with type 2 diabetes treated with the sodium glucose co-transporter 2 inhibitor canagliflozin.

scientific article published on 17 January 2018

Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia

scientific article

Ketone body metabolism and cardiovascular disease

scientific article published on 8 February 2013

Lactate metabolism is associated with mammalian mitochondria

scientific article published on 12 September 2016

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure

scientific article published on 30 November 2017

Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding

scientific article

Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease ⬇️

scientific article published on July 1, 2012

Metabolic stress in the myocardium: adaptations of gene expression.

scientific article

Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics

scientific article published on February 2017

Nuclear Receptor DAX-1 Recruits Nuclear Receptor Corepressor N-CoR to Steroidogenic Factor 1 ⬇️

scientific article published on May 1, 1998

Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage

scientific article published on July 1997

Obligate role for ketone body oxidation in neonatal metabolic homeostasis

scientific journal article

PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

scientific article published on 09 May 2013

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

scholarly article

Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation

scholarly article

Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet

scientific article

Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation

scientific article published on 11 December 2012

The Failing Heart Relies on Ketone Bodies as a Fuel

scientific article published on 27 January 2016

The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1.

scientific article

The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense

scientific article published on 21 February 2019

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

scientific article

X13CMS: global tracking of isotopic labels in untargeted metabolomics

scientific article published on 24 January 2014

List of works by Peter A Crawford

Akt2 deficiency promotes cardiac induction of Rab4a and myocardial β-adrenergic hypersensitivity.

Cardiomyocyte-specific deficiency of ketone body metabolism promotes accelerated pathological remodeling.

Circulating acylcarnitine profile in human heart failure: a surrogate of fatty acid metabolic dysregulation in mitochondria and beyond

Comprehensive and Quantitative Analysis of Polyphosphoinositide Species by Shotgun Lipidomics Revealed Their Alterations in db/db Mouse Brain.

Coordinated regulation of the metabolome and lipidome at the host-microbial interface

DEAD-box protein-103 (DP103, Ddx20) is essential for early embryonic development and modulates ovarian morphology and function

Developmental and Physiologic Roles of the Nuclear Receptor Steroidogenic Factor-1 in the Reproductive System

Hepatic steatosis, inflammation, and ER stress in mice maintained long term on a very low-carbohydrate ketogenic diet.

Impact of peripheral ketolytic deficiency on hepatic ketogenesis and gluconeogenesis during the transition to birth.

Impairments of hepatic gluconeogenesis and ketogenesis in PPARα-deficient neonatal mice

Intra- and inter-subject variability for increases in serum ketone bodies in patients with type 2 diabetes treated with the sodium glucose co-transporter 2 inhibitor canagliflozin.

Ketogenesis prevents diet-induced fatty liver injury and hyperglycemia

Ketone body metabolism and cardiovascular disease

Lactate metabolism is associated with mammalian mitochondria

Lipidomics reveals a systemic energy deficient state that precedes neurotoxicity in neonatal monkeys after sevoflurane exposure

Liver-specific PGC-1beta deficiency leads to impaired mitochondrial function and lipogenic response to fasting-refeeding

Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease ⬇️

Metabolic stress in the myocardium: adaptations of gene expression.

Multi-dimensional Roles of Ketone Bodies in Fuel Metabolism, Signaling, and Therapeutics

Nuclear Receptor DAX-1 Recruits Nuclear Receptor Corepressor N-CoR to Steroidogenic Factor 1 ⬇️

Nuclear receptor steroidogenic factor 1 directs embryonic stem cells toward the steroidogenic lineage

Obligate role for ketone body oxidation in neonatal metabolic homeostasis

PGC-1β and ChREBP partner to cooperatively regulate hepatic lipogenesis in a glucose concentration-dependent manner

Postnatal lymphatic partitioning from the blood vasculature in the small intestine requires fasting-induced adipose factor

Regulation of myocardial ketone body metabolism by the gut microbiota during nutrient deprivation

Role of choline deficiency in the Fatty liver phenotype of mice fed a low protein, very low carbohydrate ketogenic diet

Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation

The Failing Heart Relies on Ketone Bodies as a Fuel

The activation function-2 hexamer of steroidogenic factor-1 is required, but not sufficient for potentiation by SRC-1.

The failing heart utilizes 3-hydroxybutyrate as a metabolic stress defense

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease

X13CMS: global tracking of isotopic labels in untargeted metabolomics