List of works - Maria Li Lung

A modified procedure for the propagation of wild type Epstein-Barr virus in cultures of marmoset blood cells.

scientific article published in February 1994

A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation

scientific article published on 24 October 2013

A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma.

scientific article published on 5 March 2015

Analysis of Epstein-Barr virus in localized nasopharyngeal carcinoma tumors.

scientific article published in February 1993

Analysis of L-myc and GSTM1 genotypes in Chinese non-small cell lung carcinoma patients.

scientific article published in November 1996

Analysis of the genomes of mink cell focus-inducing murine type-C viruses: a progress report

scientific article published on 01 January 1980

Apoptosis and expression of cytokines triggered by pyropheophorbide-a methyl ester-mediated photodynamic therapy in nasopharyngeal carcinoma cells.

scientific article published on 17 October 2006

BRCA2 loss-of-function germline mutations are associated with esophageal squamous cell carcinoma risk in Chinese

scientific article published on 26 August 2019

Characterization of a new SNP c767A/T (Arg222Trp) in the candidate TSG FUS2 on human chromosome 3p21.3: prevalence in Asian populations and analysis of association with nasopharyngeal cancer

scientific article

Circulating Epstein-Barr virus microRNAs miR-BART7 and miR-BART13 as biomarkers for nasopharyngeal carcinoma diagnosis and treatment.

scientific article published on 18 September 2014

Clinical Outcome-Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma

scientific article published on 28 September 2020

Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma.

scientific article published on 29 April 2015

Comparative p53 mutational spectra in aerodigestive tract tumors in Hong Kong Chinese patients

scientific article published on 01 January 1999

Corrigendum to "A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma".

scientific article published on 4 July 2016

Cylindromatosis Lysine 63 Deubiquitinase (CYLD) Regulates NF-kB Signaling Pathway and Modulates Fibroblast and Endothelial Cells Recruitment in Nasopharyngeal Carcinoma

scientific article published on 16 July 2020

DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma

scientific article published on 9 February 2016

Detection and evaluation of p53 intron 2 polymorphism in lung carcinomas in Hong Kong

scientific article published on 01 April 1996

Detection and prevalence of the “f” variant of epstein-barr virus in Southern China ⬇️

scientific article published on November 1, 1991

Detection of distinct Epstein-Barr virus genotypes in NPC biopsies from southern Chinese and Caucasians

scientific article published on August 19, 1992

Detection of p53 mutations in Hong Kong colorectal carcinomas by conventional PCR-SSCP analysis versus p53 yeast functional assays

scientific article published on 01 January 1999

EBV infection is associated with histone bivalent switch modifications in squamous epithelial cells

scientific article published on 24 June 2019

Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma.

scientific article published on 15 December 2017

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

scientific article

Epigenetic markers for noninvasive early detection of nasopharyngeal carcinoma by methylation-sensitive high resolution melting.

scientific article published on 19 September 2014

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways

scientific article published on 4 January 2017

Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation.

scientific article

Evaluation and optimization of a latex agglutination assay for detection of cholera toxin and Escherichia coli heat-labile toxin ⬇️

scientific article published on September 1, 1992

Evaluation of circulating EBV microRNA BART2-5p in facilitating early detection and screening of nasopharyngeal carcinoma

scientific article published on 15 November 2018

Expression of Epstein‐Barr virus‐encodedLMP1andhTERTextends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells ⬇️

scientific article published on October 1, 2010

Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-regulation of BLU in some esophageal squamous cell carcinomas

scientific article

FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression

scientific article published on 07 September 2020

Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.

scientific article

Frequent loss of heterozygosity on chromosome 9 in Chinese esophageal squamous cell carcinomas.

scientific article

Frequent loss of heterozygosity on multiple chromosomes in Chinese esophageal squamous cell carcinomas

scientific article published on 01 September 2001

Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.

scientific article

Genetic and epigenetic landscape of nasopharyngeal carcinoma.

scientific article published on April 2016

Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma.

scientific article published in August 1999

Genotypic analysis of Epstein-Barr virus isolates associated with nasopharyngeal carcinoma in Chinese immigrants to the United States.

scientific article published in December 1994

IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling.

scientific article published on 31 July 2015

Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9

scientific article

Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma.

scientific article published on 29 May 2014

In vitro aflatoxin B1-induced p53 mutations

scientific article published on 01 September 2003

Inactivation mechanisms and growth suppressive effects of p16INK4a in Asian esophageal squamous carcinoma cell lines.

scientific article published on May 2004

Incidence of ras oncogene activation in lung carcinomas in Hong Kong

scientific article published on 01 August 1992

Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir

scientific article published on 23 July 2015

Involvement of both endoplasmic reticulum and mitochondria in photokilling of nasopharyngeal carcinoma cells by the photosensitizer Zn-BC-AM.

scientific article published in December 2004

Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients

scientific article published on 01 December 1998

L-myc genotypes in Hong Kong Chinese colorectal carcinoma patients

scientific article published on 01 March 1999

LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma.

scientific article

Large RNase T1-resistant oligonucleotides encoding p15E and the U3 region of the long terminal repeat distinguish two biological classes of mink cell focus-forming type C viruses of inbred mice.

scientific article published on January 1983

Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese

scientific article published on 07 August 2018

Liquid Biopsy Serial Monitoring of Treatment Responses and Relapse in Advanced Esophageal Squamous Cell Carcinoma

scientific article published on 26 May 2020

Mapping of nasopharyngeal carcinoma tumor-suppressive activity to a 1.8-megabase region of chromosome band 11q13

scientific article published on 01 May 2002

Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl) sulfonate (PCS) Part I: Construction and characterization of the microbial sensor

scientific article published on 01 February 1999

Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl)sulfonate (PCS). Part II: Application of the novel biosensor to real samples from coastal and island re

scientific article

Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells.

scientific article

Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma

scientific article published on 25 October 2016

Microsatellite allelotyping of chinese nasopharyngeal carcinomas

scientific article published on 01 July 2001

Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population

scientific article published on 05 May 2007

Milk consumption in relation to incidence of nasopharyngeal carcinoma in 48 countries/regions

scientific article published on 21 December 2015

Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line.

scientific article

NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells

scientific article published on 14 May 2015

Nucleotide sequence of the 3' end of MCF 247 murine leukemia virus.

scientific article published on January 1983

PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy

scientific article published on 26 August 2013

Photodynamic therapy-mediated modulation of inflammatory cytokine production by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.

scientific article published on 15 March 2010

Physicochemical, biological and serological properties of a leukemogenic virus isolated from cultured radl-V-induced lymphomas of C57BL/Ka mice ⬇️

scientific article published on October 1, 1978

Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma

scientific article

Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma.

scientific article published in December 2017

Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins.

scientific article

Reduced expression of RASSF1A in esophageal and nasopharyngeal carcinomas significantly correlates with tumor stage

scientific article published on 27 August 2007

Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres.

scientific article published on 8 February 2013

Role of STAT3/5 and Bcl‐2/xL in 2‐methoxyestradiol‐induced endoreduplication of nasopharyngeal carcinoma cells ⬇️

scientific article published on October 17, 2011

Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation

scientific article published on 31 July 2020

Role of mitogen-activated protein kinase in Zn-BC-AM PDT-induced apoptosis in nasopharyngeal carcinoma cells.

scientific article published on April 2010

Secular trends of salted fish consumption and nasopharyngeal carcinoma: a multi-jurisdiction ecological study in 8 regions from 3 continents

scientific article

Study of Epstein-Barr Virus (EBV) Transmission by EBV Genotyping ⬇️

scientific article published on July 1, 1991

Succinct workflows for circulating tumor cells after enrichment: From systematic counting to mutational profiling

scientific article

Targeted inhibition of the EGFR pathways enhances Zn-BC-AM PDT-induced apoptosis in well-differentiated nasopharyngeal carcinoma cells.

scientific article published on December 2009

Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study.

scientific article

The ECM protein LTBP-2 is a suppressor of esophageal squamous cell carcinoma tumor formation but higher tumor expression associates with poor patient outcome.

scientific article published on 9 November 2010

The association of CYP2C9 gene polymorphisms with colorectal carcinoma in Han Chinese

scientific article published on 22 February 2007

Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin

scientific article published on 21 April 2015

Tissue distribution of Epstein-Barr virus genotypes.

scientific article

Transcription of BamHI-A region of the EBV genome in NPC tissues and B cells.

scientific article published in November 1992

Tumor suppressive role of a 2.4 Mb 9q33-q34 critical region and DEC1 in esophageal squamous cell carcinoma.

scientific article

Unlocking the Rosetta Stone enigma for nasopharyngeal carcinoma: Genetics, viral infection, and epidemiological factors ⬇️

scientific article published on January 14, 2012

Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma

scientific article published on 7 March 2016

Whole-exome sequencing identifies multiple loss-of-function mutations of NF-κB pathway regulators in nasopharyngeal carcinoma.

scientific article published on 19 September 2016

Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma

scientific article published on 13 June 2017

Wnt-C59 arrests stemness and suppresses growth of nasopharyngeal carcinoma in mice by inhibiting the Wnt pathway in the tumor microenvironment.

scientific article published on June 2015

p53 inactivating mutations in Chinese nasopharyngeal carcinomas

scientific article published on 01 November 1998

p53 intron 2 genotypes detected in normal specimens and lung carcinomas in Hong Kong

scientific article published on 01 September 1998

p53 mutational spectrum of esophageal carcinomas from five different geographical locales in China.

scientific article published in April 1996

p53 mutations detected in colorectal carcinoma patients in Hong Kong

scientific article published on 01 November 1997

List of works by Maria Li Lung

A modified procedure for the propagation of wild type Epstein-Barr virus in cultures of marmoset blood cells.

A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation

A versatile orthotopic nude mouse model for study of esophageal squamous cell carcinoma.

Analysis of Epstein-Barr virus in localized nasopharyngeal carcinoma tumors.

Analysis of L-myc and GSTM1 genotypes in Chinese non-small cell lung carcinoma patients.

Analysis of the genomes of mink cell focus-inducing murine type-C viruses: a progress report

Apoptosis and expression of cytokines triggered by pyropheophorbide-a methyl ester-mediated photodynamic therapy in nasopharyngeal carcinoma cells.

BRCA2 loss-of-function germline mutations are associated with esophageal squamous cell carcinoma risk in Chinese

Characterization of a new SNP c767A/T (Arg222Trp) in the candidate TSG FUS2 on human chromosome 3p21.3: prevalence in Asian populations and analysis of association with nasopharyngeal cancer

Circulating Epstein-Barr virus microRNAs miR-BART7 and miR-BART13 as biomarkers for nasopharyngeal carcinoma diagnosis and treatment.

Clinical Outcome-Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma

Comparative methylome analysis in solid tumors reveals aberrant methylation at chromosome 6p in nasopharyngeal carcinoma.

Comparative p53 mutational spectra in aerodigestive tract tumors in Hong Kong Chinese patients

Corrigendum to "A Versatile Orthotopic Nude Mouse Model for Study of Esophageal Squamous Cell Carcinoma".

Cylindromatosis Lysine 63 Deubiquitinase (CYLD) Regulates NF-kB Signaling Pathway and Modulates Fibroblast and Endothelial Cells Recruitment in Nasopharyngeal Carcinoma

DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma

Detection and evaluation of p53 intron 2 polymorphism in lung carcinomas in Hong Kong

Detection and prevalence of the “f” variant of epstein-barr virus in Southern China ⬇️

Detection of distinct Epstein-Barr virus genotypes in NPC biopsies from southern Chinese and Caucasians

Detection of p53 mutations in Hong Kong colorectal carcinomas by conventional PCR-SSCP analysis versus p53 yeast functional assays

EBV infection is associated with histone bivalent switch modifications in squamous epithelial cells

Elevated levels of serum nidogen-2 in esophageal squamous cell carcinoma.

Epigenetic disruption of interferon-gamma response through silencing the tumor suppressor interferon regulatory factor 8 in nasopharyngeal, esophageal and multiple other carcinomas.

Epigenetic markers for noninvasive early detection of nasopharyngeal carcinoma by methylation-sensitive high resolution melting.

Epstein-Barr Virus-Encoded Latent Membrane Protein 1 Upregulates Glucose Transporter 1 Transcription via the mTORC1/NF-κB Signaling Pathways

Establishment of a nasopharyngeal carcinoma cell line capable of undergoing lytic Epstein-Barr virus reactivation.

Evaluation and optimization of a latex agglutination assay for detection of cholera toxin and Escherichia coli heat-labile toxin ⬇️

Evaluation of circulating EBV microRNA BART2-5p in facilitating early detection and screening of nasopharyngeal carcinoma

Expression of Epstein‐Barr virus‐encodedLMP1andhTERTextends the life span and immortalizes primary cultures of nasopharyngeal epithelial cells ⬇️

Expression of candidate chromosome 3p21.3 tumor suppressor genes and down-regulation of BLU in some esophageal squamous cell carcinomas

FANCD2 Confers a Malignant Phenotype in Esophageal Squamous Cell Carcinoma by Regulating Cell Cycle Progression

Frequent decreased expression of candidate tumor suppressor gene, DEC1, and its anchorage-independent growth properties and impact on global gene expression in esophageal carcinoma.

Frequent loss of heterozygosity on chromosome 9 in Chinese esophageal squamous cell carcinomas.

Frequent loss of heterozygosity on multiple chromosomes in Chinese esophageal squamous cell carcinomas

Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.

Genetic and epigenetic landscape of nasopharyngeal carcinoma.

Genomic instability and alterations in Apc, Mcc and Dcc in Hong Kong patients with colorectal carcinoma.

Genotypic analysis of Epstein-Barr virus isolates associated with nasopharyngeal carcinoma in Chinese immigrants to the United States.

IKBB tumor suppressive role in nasopharyngeal carcinoma via NF-κB-mediated signalling.

Identification of a tumor suppressive critical region mapping to 3p14.2 in esophageal squamous cell carcinoma and studies of a candidate tumor suppressor gene, ADAMTS9

Identity-by-descent approaches identify regions of importance for genetic susceptibility to hereditary esophageal squamous cell carcinoma.

In vitro aflatoxin B1-induced p53 mutations

Inactivation mechanisms and growth suppressive effects of p16INK4a in Asian esophageal squamous carcinoma cell lines.

Incidence of ras oncogene activation in lung carcinomas in Hong Kong

Inhibition of class I histone deacetylases by romidepsin potently induces Epstein-Barr virus lytic cycle and mediates enhanced cell death with ganciclovir

Involvement of both endoplasmic reticulum and mitochondria in photokilling of nasopharyngeal carcinoma cells by the photosensitizer Zn-BC-AM.

Ki-ras codon 12 point mutational activation in Hong Kong colorectal carcinoma patients

L-myc genotypes in Hong Kong Chinese colorectal carcinoma patients

LTBP-2 confers pleiotropic suppression and promotes dormancy in a growth factor permissive microenvironment in nasopharyngeal carcinoma.

Large RNase T1-resistant oligonucleotides encoding p15E and the U3 region of the long terminal repeat distinguish two biological classes of mink cell focus-forming type C viruses of inbred mice.

Leukocyte telomere length associates with nasopharyngeal carcinoma risk and survival in Hong Kong Chinese

Liquid Biopsy Serial Monitoring of Treatment Responses and Relapse in Advanced Esophageal Squamous Cell Carcinoma

Mapping of nasopharyngeal carcinoma tumor-suppressive activity to a 1.8-megabase region of chromosome band 11q13

Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl) sulfonate (PCS) Part I: Construction and characterization of the microbial sensor

Measurement of biodegradable substances using the salt-tolerant yeast Arxula adeninivorans for a microbial sensor immobilized with poly(carbamoyl)sulfonate (PCS). Part II: Application of the novel biosensor to real samples from coastal and island re

Mechanisms of 2-methoxyestradiol-induced apoptosis and G2/M cell-cycle arrest of nasopharyngeal carcinoma cells.

Metastasis-suppressing NID2, an epigenetically-silenced gene, in the pathogenesis of nasopharyngeal carcinoma and esophageal squamous cell carcinoma

Microsatellite allelotyping of chinese nasopharyngeal carcinomas

Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population

Milk consumption in relation to incidence of nasopharyngeal carcinoma in 48 countries/regions

Mutant p53 expression enhances drug resistance in a hepatocellular carcinoma cell line.

NF-κB p65 Subunit Is Modulated by Latent Transforming Growth Factor-β Binding Protein 2 (LTBP2) in Nasopharyngeal Carcinoma HONE1 and HK1 Cells

Nucleotide sequence of the 3' end of MCF 247 murine leukemia virus.

PARP1 is overexpressed in nasopharyngeal carcinoma and its inhibition enhances radiotherapy

Photodynamic therapy-mediated modulation of inflammatory cytokine production by Epstein-Barr virus-infected nasopharyngeal carcinoma cells.

Physicochemical, biological and serological properties of a leukemogenic virus isolated from cultured radl-V-induced lymphomas of C57BL/Ka mice ⬇️

Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma

Prospective, Multicenter, Phase 2 Trial of Induction Chemotherapy Followed by Bio-Chemoradiotherapy for Locally Advanced Recurrent Nasopharyngeal Carcinoma.

Proteomic analysis of exosomes from nasopharyngeal carcinoma cell identifies intercellular transfer of angiogenic proteins.

Reduced expression of RASSF1A in esophageal and nasopharyngeal carcinomas significantly correlates with tumor stage

Role of MIF/CXCL8/CXCR2 signaling in the growth of nasopharyngeal carcinoma tumor spheres.

Role of STAT3/5 and Bcl‐2/xL in 2‐methoxyestradiol‐induced endoreduplication of nasopharyngeal carcinoma cells ⬇️

Role of miR-96/EVI1/miR-449a Axis in the Nasopharyngeal Carcinoma Cell Migration and Tumor Sphere Formation

Role of mitogen-activated protein kinase in Zn-BC-AM PDT-induced apoptosis in nasopharyngeal carcinoma cells.

Secular trends of salted fish consumption and nasopharyngeal carcinoma: a multi-jurisdiction ecological study in 8 regions from 3 continents

Study of Epstein-Barr Virus (EBV) Transmission by EBV Genotyping ⬇️

Succinct workflows for circulating tumor cells after enrichment: From systematic counting to mutational profiling

Targeted inhibition of the EGFR pathways enhances Zn-BC-AM PDT-induced apoptosis in well-differentiated nasopharyngeal carcinoma cells.

Test-retest reliability of a computer-assisted self-administered questionnaire on early life exposure in a nasopharyngeal carcinoma case-control study.