List of works - Barbara Guerra

A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures

scientific article

Ability of CK2beta to selectively regulate cellular protein kinases.

scientific article

Acetoxymethyl Ester of Tetrabromobenzimidazole-Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells

scientific article published on 12 November 2015

Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells

scientific article published on 01 September 2018

CK2: a protein kinase in need of control.

scientific article

Characterization of CK2 holoenzyme variants with regard to crystallization.

scientific article published in November 2001

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

scientific article

Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

scientific article

Cytotoxic effects exerted by pentachlorophenol by targeting nodal pro-survival signaling pathways in human pancreatic cancer cells

scientific article published on 6 November 2014

D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells.

scientific article published on January 2017

Delivery of proteins encapsulated in chitosan-tripolyphosphate nanoparticles to human skin melanoma cells

scientific article published on 03 November 2018

Determination of mRNA, and protein levels of p53, MDM2 and protein kinase CK2 subunits in F9 cells after treatment with the apoptosis-inducing drugs cisplatin and carboplatin.

scientific article published on June 1999

Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2

scientific article published on 01 November 1995

Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes

scientific article published on 10 October 2019

Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action

scientific article published on 30 August 2006

Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

scientific article

Epitope analysis of the MAb 1AD9 antibody detection site in human protein kinase CK2alpha-subunit.

scientific article

Essential role of CK2α for the interaction and stability of replication fork factors during DNA synthesis and activation of the S-phase checkpoint

scientific article published on 04 June 2022

Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET(2).

scientific article published on 23 August 2014

Expression, purification and crystallization of the catalytic subunit of protein kinase CK2 from Zea mays

scientific article published on 01 January 1998

GTP plus water mimic ATP in the active site of protein kinase CK2

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Hierarchical phosphorylation of a 50-kDa protein by protein tyrosine kinases TPK-IIB and C-Fgr, and its identification as HS1 hematopoietic-lineage cell-specific protein

scientific journal article

Identification of a novel potent, selective and cell permeable inhibitor of protein kinase CK2 from the NIH/NCI Diversity Set Library

scientific article published on 12 May 2015

Mapping the residues of protein kinase CK2 implicated in substrate recognition: mutagenesis of conserved basic residues in the alpha-subunit

scientific article published on 01 January 1995

Natural Compounds and Derivatives as Ser/Thr Protein Kinase Modulators and Inhibitors

scientific article published on 01 January 2019

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma

scientific article

Phosphorylation of the Fas associated factor FAF1 by protein kinase CK2 and identification of serines 289 and 291 as the in vitro phosphorylation sites

scientific article (publication date: June 2001)

Phosphorylation of the regulatory beta-subunit of protein kinase CK2 by checkpoint kinase Chk1: identification of the in vitro CK2beta phosphorylation site

scientific article

Protein kinase CK2 in human diseases.

scientific article published on January 2008

Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs.

scientific article published on 11 December 2013

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

scientific article

Protein kinase CK2 regulates redox homeostasis through NF-κB and Bcl-xL in cardiomyoblasts.

scientific article published on 8 June 2017

Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles

scientific article published on 01 December 1999

Psoralen—fatty acid cycloadducts activate protein kinase C (PKC) in human platelets

scientific article published on 01 March 1994

Purification and characterization of recombinant protein kinase CK2 from Zea mays expressed in Escherichia coli.

scientific article published in May 2003

Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells

scientific article

Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts.

scientific article published on 9 September 2010

Resorufin: a lead for a new protein kinase CK2 inhibitor

scientific article

Role of Protein Kinase CK2 in Aberrant Lipid Metabolism in Cancer

scientific article published on 05 October 2020

Role of polyamines in determining the cellular response to chemotherapeutic agents: modulation of protein kinase CK2 expression and activity.

scientific article published on 13 July 2011

Simultaneous dissection and comparison of IL-2 and IL-15 signaling pathways by global quantitative phosphoproteomics

scientific article published on 30 September 2014

Structural basis of the constitutive activity of protein kinase CK2.

scientific article published on January 2010

The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer

scientific article

The Yin and Yang of redox regulation.

scientific article published on January 2013

The antipsychotic drug chlorpromazine enhances the cytotoxic effect of tamoxifen in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells

scientific article

The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation

scientific article published on 01 June 1997

The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment

scientific article published on 20 October 2015

The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis.

scientific article published on 12 May 2008

The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.

scientific article

The spleen protein-tyrosine kinase TPK-IIB is highly similar to the catalytic domain of p72syk

scientific article published on 01 September 1996

Validation of protein kinase CK2 as oncological target.

scientific article published in August 2005

List of works by Barbara Guerra

A Note of Caution on the Role of Halogen Bonds for Protein Kinase/Inhibitor Recognition Suggested by High- And Low-Salt CK2α Complex Structures

Ability of CK2beta to selectively regulate cellular protein kinases.

Acetoxymethyl Ester of Tetrabromobenzimidazole-Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells

Blocking of an intronic splicing silencer completely rescues IKBKAP exon 20 splicing in familial dysautonomia patient cells

CK2: a protein kinase in need of control.

Characterization of CK2 holoenzyme variants with regard to crystallization.

Crystal structure of human protein kinase CK2: insights into basic properties of the CK2 holoenzyme

Crystal structure of the catalytic subunit of protein kinase CK2 from Zea mays at 2.1 A resolution.

Cytotoxic effects exerted by pentachlorophenol by targeting nodal pro-survival signaling pathways in human pancreatic cancer cells

D11-Mediated Inhibition of Protein Kinase CK2 Impairs HIF-1α-Mediated Signaling in Human Glioblastoma Cells.

Delivery of proteins encapsulated in chitosan-tripolyphosphate nanoparticles to human skin melanoma cells

Determination of mRNA, and protein levels of p53, MDM2 and protein kinase CK2 subunits in F9 cells after treatment with the apoptosis-inducing drugs cisplatin and carboplatin.

Different susceptibility of protein kinases to staurosporine inhibition. Kinetic studies and molecular bases for the resistance of protein kinase CK2

Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes

Emodin negatively affects the phosphoinositide 3-kinase/AKT signalling pathway: a study on its mechanism of action

Enhancing chemosensitivity to gemcitabine via RNA interference targeting the catalytic subunits of protein kinase CK2 in human pancreatic cancer cells

Epitope analysis of the MAb 1AD9 antibody detection site in human protein kinase CK2alpha-subunit.

Essential role of CK2α for the interaction and stability of replication fork factors during DNA synthesis and activation of the S-phase checkpoint

Evidence for aggregation of protein kinase CK2 in the cell: a novel strategy for studying CK2 holoenzyme interaction by BRET(2).

Expression, purification and crystallization of the catalytic subunit of protein kinase CK2 from Zea mays

GTP plus water mimic ATP in the active site of protein kinase CK2

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Hierarchical phosphorylation of a 50-kDa protein by protein tyrosine kinases TPK-IIB and C-Fgr, and its identification as HS1 hematopoietic-lineage cell-specific protein

Identification of a novel potent, selective and cell permeable inhibitor of protein kinase CK2 from the NIH/NCI Diversity Set Library

Mapping the residues of protein kinase CK2 implicated in substrate recognition: mutagenesis of conserved basic residues in the alpha-subunit

Natural Compounds and Derivatives as Ser/Thr Protein Kinase Modulators and Inhibitors

Nuclear localization of the CK2α-subunit correlates with poor prognosis in clear cell renal cell carcinoma

Phosphorylation of the Fas associated factor FAF1 by protein kinase CK2 and identification of serines 289 and 291 as the in vitro phosphorylation sites

Phosphorylation of the regulatory beta-subunit of protein kinase CK2 by checkpoint kinase Chk1: identification of the in vitro CK2beta phosphorylation site

Protein kinase CK2 in human diseases.

Protein kinase CK2 is required for the recruitment of 53BP1 to sites of DNA double-strand break induced by radiomimetic drugs.

Protein kinase CK2 localizes to sites of DNA double-strand break regulating the cellular response to DNA damage

Protein kinase CK2 regulates redox homeostasis through NF-κB and Bcl-xL in cardiomyoblasts.

Protein kinase CK2: evidence for a protein kinase CK2beta subunit fraction, devoid of the catalytic CK2alpha subunit, in mouse brain and testicles

Psoralen—fatty acid cycloadducts activate protein kinase C (PKC) in human platelets

Purification and characterization of recombinant protein kinase CK2 from Zea mays expressed in Escherichia coli.

Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells

Regulation of taurine homeostasis by protein kinase CK2 in mouse fibroblasts.

Resorufin: a lead for a new protein kinase CK2 inhibitor

Role of Protein Kinase CK2 in Aberrant Lipid Metabolism in Cancer

Role of polyamines in determining the cellular response to chemotherapeutic agents: modulation of protein kinase CK2 expression and activity.

Simultaneous dissection and comparison of IL-2 and IL-15 signaling pathways by global quantitative phosphoproteomics

Structural basis of the constitutive activity of protein kinase CK2.

The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer

The Yin and Yang of redox regulation.

The antipsychotic drug chlorpromazine enhances the cytotoxic effect of tamoxifen in tamoxifen-sensitive and tamoxifen-resistant human breast cancer cells

The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation

The kinase inhibitor D11 induces caspase-mediated cell death in cancer cells resistant to chemotherapeutic treatment

The regulatory beta-subunit of protein kinase CK2 regulates cell-cycle progression at the onset of mitosis.

The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.

The spleen protein-tyrosine kinase TPK-IIB is highly similar to the catalytic domain of p72syk

Validation of protein kinase CK2 as oncological target.