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List of works by Nunilo Cremades

A natural product inhibits the initiation of α-synuclein aggregation and suppresses its toxicity

scientific article

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

scientific article published on 12 November 2015

Antiparasitic drug nitazoxanide inhibits the pyruvate oxidoreductases of Helicobacter pylori, selected anaerobic bacteria and parasites, and Campylobacter jejuni

scientific article

Cell surface localised Hsp70 is a cancer specific regulator of clathrin-independent endocytosis

scientific article published on 6 August 2015

Common conformational changes in flavodoxins induced by FMN and anion binding: the structure of Helicobacter pylori apoflavodoxin

scientific article

Conformational stability of Helicobacter pylori flavodoxin: fit to function at pH 5.

scientific article published on 11 November 2007

Direct observation of the interconversion of normal and toxic forms of α-synuclein

scientific article

Discovery of specific flavodoxin inhibitors as potential therapeutic agents against Helicobacter pylori infection

scientific article

Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers

scientific article published on 10 August 2015

Flavodoxin:quinone reductase (FqrB): a redox partner of pyruvate:ferredoxin oxidoreductase that reversibly couples pyruvate oxidation to NADPH production in Helicobacter pylori and Campylobacter jejuni

scientific article

Hsp70 oligomerization is mediated by an interaction between the interdomain linker and the substrate-binding domain

scientific article

Identification of pharmacological chaperones as potential therapeutic agents to treat phenylketonuria

scientific article published on August 2008

Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme

Local cooperativity in an amyloidogenic state of human lysozyme observed at atomic resolution

scientific article

Molten globule and native state ensemble of Helicobacter pylori flavodoxin: can crowding, osmolytes or cofactors stabilize the native conformation relative to the molten globule?

scientific article

Multiplicity of α-Synuclein Aggregated Species and Their Possible Roles in Disease

scientific article published on 28 October 2020

Multistep Inhibition of α-Synuclein Aggregation and Toxicity in Vitro and in Vivo by Trodusquemine

article

Nanobodies Raised against Monomeric α-Synuclein Distinguish between Fibrils at Different Maturation Stages

scientific article published on 01 April 2013

Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions

scientific article published on 18 November 2019

On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and lacmoid

scientific article published in September 2009

Population of nonnative states of lysozyme variants drives amyloid fibril formation

scientific article published on 29 April 2011

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants

scientific article

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers

scientific article

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.

scientific article published on 8 April 2015

Structure and properties of a complex of α-synuclein and a single-domain camelid antibody

scientific article

Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease

scientific article

The flavodoxin from Helicobacter pylori: structural determinants of thermostability and FMN cofactor binding.

scientific article published on 21 December 2007

The native-state ensemble of proteins provides clues for folding, misfolding and function

scientific article published on 25 July 2006

The release of toxic oligomers from α-synuclein fibrils induces dysfunction in neuronal cells

scientific article published on 22 March 2021

Towards a new therapeutic target: Helicobacter pylori flavodoxin.

scientific article

Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism

scientific article published on 13 August 2020

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