List of works - Marina Carini

"In vitro" metabolism of bezafibrate by rat liver

scientific article published on 01 February 1981

2020 Italian Special Anniversary Collection: Celebrating NMMC 2019 and 40 Years of the DCF-SCI

scientific article published on 23 December 2020

A Combined High-Resolution Mass Spectrometric and in silico Approach for the Characterisation of Small Ligands of β2-Microglobulin

scientific article published on 01 July 2010

A novel high resolution MS approach for the screening of 4-hydroxy-trans-2-nonenal sequestering agents

scientific article published in January 2014

A novel truncated form of eNOS associates with altered vascular function

scientific article published on 03 December 2013

A rapid and sensitive LC-ESI-MS/MS method for detection and quantitation of methylprednisolone and methylprednisolone acetate in rat plasma after intra-articular administration.

scientific article published on 2 October 2009

A sensitive and specific precursor ion scanning approach in liquid chromatography/electrospray ionization tandem mass spectrometry to detect methylprednisolone acetate and its metabolites in rat urine

scientific article published in June 2010

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

scientific article published on 18 August 2010

Acrolein‐sequestering ability of endogenous dipeptides: characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry ⬇️

scientific article published on September 1, 2003

Actin Cys374 as a nucleophilic target of α,β-unsaturated aldehydes

scientific article published on 30 November 2006

Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry

scientific article published on 28 December 2013

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.

scientific article

Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why

scientific article published on 18 December 2018

Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species?

scientific article published on 7 March 2008

An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract.

scientific article published on 3 March 2011

Analysis of tiadenol in human plasma by capillary gas chromatography with electron capture detection

scientific article published on 01 January 1987

Anti-Elastase and Anti-Hyaluronidase Activities of Saponins and Sapogenins fromHedera helix, Aesculus hippocastanum, andRuscus aculeatus: Factors Contributing to their Efficacy in the Treatment of Venous Insufficiency

scientific article published on 01 October 1995

Antioxidant and photoprotective activity of a lipophilic extract containing neolignans from Krameria triandra roots.

scientific article published on March 2002

Carboxylic metabolites of tiadenol as "proximate" inducers of hepatic peroxisomal beta-oxidation activity

scientific article published on 01 April 1988

Characterization of cisplatin-glutathione adducts by liquid chromatography-mass spectrometry. Evidence for their formation in vitro but not in vivo after concomitant administration of cisplatin and glutathione to rats anc cancer patients

scientific article published on 01 July 1995

Chemiluminescence and LC-MS/MS analyses for the study of nitric oxide release and distribution following oral administration of nitroaspirin (NCX 4016) in healthy volunteers

scientific article (publication date: 16 April 2004)

Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction

scientific article published in July 2005

Decrease in hepatic microsomal UDP-glucuronosyl-transferase activity in rats and cattle with fascioliasis: impaired in vitro glucuronidation of oxyclozanide

scientific article published on 01 July 1985

Decrease of the in vitro drug-metabolizing activity of the hepatic mixed function oxidase system in rats infected experimentally with Fasciola hepatica: pharmacological implications

scientific article published on 01 September 1981

Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146

scientific article

Design, synthesis, ADME properties, and pharmacological activities of β-alanyl-D-histidine (D-carnosine) prodrugs with improved bioavailability

scientific article published in June 2011

Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species

scientific article published in June 2009

Determination of sunscreen agents by micellar electrokinetic chromatography

scientific article published on 01 March 1995

Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle.

scientific article

Development and validation of a sensitive LC-MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study

article

Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats

scientific article published on 01 January 1999

Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms

scientific article published in March 2010

Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers.

scientific article published in October 2003

Effect of the hypolipidemic drug bezafibrate on the hepatic mixed function oxidase system of the rat: heterogeneity monooxygenase responses.

scientific article

Effects of UVB radiation on 4-hydroxy-2-trans-nonenal metabolism and toxicity in human keratinocytes.

scientific article published on 17 February 2007

Electron Spin Resonance and Chemiluminescence Analyses to Elucidate the Vasodilating Mechanism of Sodium Nitroprusside

scientific article published on 01 August 2006

Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents

scientific article published on 30 May 2013

Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure.

scientific article

Further studies on adriamycin induced in vitro lipid peroxidation

scientific article published on 01 February 1982

HNE Michael adducts to histidine and histidine-containing peptides as biomarkers of lipid-derived carbonyl stress in urines: LC-MS/MS profiling in Zucker obese rats.

scientific article published on 3 November 2007

Hemoglobin glutathionylation can occur through cysteine sulfenic acid intermediate: electrospray ionization LTQ-Orbitrap hybrid mass spectrometry studies.

scientific article published on 18 May 2009

Human serum albumin cysteinylation is increased in end stage renal disease patients and reduced by hemodialysis: mass spectrometry studies

scientific article published on 09 January 2013

Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement.

scientific article published on 13 February 2007

Identification of flavonoid metabolites after oral administration to rats of a Ginkgo biloba extract

scientific article published on 01 November 1995

Impaired in vitro metabolism of the flukicidal agent nitroxynil by hepatic microsomal cytochrome P-450 in bovine fascioliasis

scientific article published on 01 March 1984

In vitro biotransformation of pyrazinamide by rat liver: identification of a new metabolite.

scientific article published on April 1981

In vitro metabolism of a nitroderivative of acetylsalicylic acid (NCX4016) by rat liver: LC and LC-MS studies

scientific article (publication date: August 2002)

Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls.

scientific article published on November 2007

Intravenous Infusion of Nitric Oxide in Experimental Pulmonary Hypertension: Biotransformation and Haemodynamics

scientific article published on 01 August 2007

LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues.

scientific article published in November 2005

Mass spectrometric approaches for the identification and quantification of reactive carbonyl species protein adducts

scientific article published on 15 April 2013

Mass spectrometric characterization and HPLC determination of the main urinary metabolites of nimesulide in man

scientific article published on 01 October 1998

Mass spectrometric characterization of covalent modification of human serum albumin by 4-hydroxy-trans-2-nonenal

scientific article published on 01 September 2006

Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies

scientific article published on 13 August 2014

Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins.

scientific article

Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study.

scientific article

Methylprednisolone‐loaded PLGA microspheres: A new formulation for sustained release via intra‐articular administration. A comparison study with methylprednisolone acetate in rats

scientific article published on 17 August 2011

Nitric oxide release and distribution following oral and intraperitoneal administration of nitroaspirin (NCX 4016) in the rat

scientific article (publication date: 14 May 2004)

Nitrosylhemoglobin as a Potential Bioactive Storage form of Nitric Oxide (NO)

scientific article published on 01 August 2005

Nitrosylhemoglobin formation after infusion of NO solutions: ESR studies in pigs.

scientific article

Nitrosylhemoglobin, an unequivocal index of nitric oxide release from nitroaspirin: in vitro and in vivo studies in the rat by ESR spectroscopy

scientific article (publication date: November 2001)

Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds

scientific article published on 21 January 2014

Panax ginseng Administration in the Rat Prevents Myocardial Ischemia-Reperfusion Damage Induced by Hyperbaric Oxygen: Evidence for an Antioxidant Intervention

article

Preservation of endothelium nitric oxide release by pulsatile flow cardiopulmonary bypass when compared with continuous flow

scientific article published on 27 October 2009

Preservation of endothelium nitric oxide release during beating heart surgery with respect to continuous flow cardiopulmonary bypass

scientific article published on 01 March 2010

Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection ⬇️

scientific article published on October 17, 2003

Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans.

scientific article published on 19 April 2009

Profiling histidine-containing dipeptides in rat tissues by liquid chromatography/electrospray ionization tandem mass spectrometry.

scientific article published in December 2004

Protein carbonylation.

scientific article

Protein carbonylation: 2,4-dinitrophenylhydrazine reacts with both aldehydes/ketones and sulfenic acids.

scientific article published on 5 March 2009

Protein haptenation by amoxicillin: High resolution mass spectrometry analysis and identification of target proteins in serum

article

Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents.

scientific article published on August 2011

Rapid analysis of alpha-hederin in a crude plant extract by collisional mass spectrometry (CAD MIKES)

scientific article published on 01 January 1985

Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug

scientific article published on 01 October 1996

Screening of fibrillogenesis inhibitors of β2-microglobulin: integrated strategies by mass spectrometry capillary electrophoresis and in silico simulations

scientific article

Searching for allergens in maize kernels via proteomic tools.

scientific article published in April 2009

Stressed degradation studies of domiphen bromide by LC-ESI-MS/MS identify a novel promising antimicrobial agent

scientific article published on 30 June 2018

The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats

scientific article

The inhibitory effect of pyrazinamide on microsomal monooxygenase activities is related to the binding to reduced cytochrome P-450

scientific article published on 01 June 1980

Transforming dietary peptides in promising lead compounds: the case of bioavailable carnosine analogs

scientific article published on July 2012

Urinary profile of methylprednisolone acetate metabolites in patients following intra-articular and intramuscular administration

scientific article published on 19 February 2011

Water-Soluble alpha,beta-unsaturated aldehydes of cigarette smoke induce carbonylation of human serum albumin.

scientific article published in March 2010

What we know about oxidative stress in patients with chronic kidney disease on dialysis--clinical effects, potential treatment, and prevention.

scientific article published on January 2011

α,β-Unsaturated aldehydes adducts to actin and albumin as potential biomarkers of carbonylation damage

scientific article published on 01 January 2007

List of works by Marina Carini

"In vitro" metabolism of bezafibrate by rat liver

2020 Italian Special Anniversary Collection: Celebrating NMMC 2019 and 40 Years of the DCF-SCI

A Combined High-Resolution Mass Spectrometric and in silico Approach for the Characterisation of Small Ligands of β2-Microglobulin

A novel high resolution MS approach for the screening of 4-hydroxy-trans-2-nonenal sequestering agents

A novel truncated form of eNOS associates with altered vascular function

A rapid and sensitive LC-ESI-MS/MS method for detection and quantitation of methylprednisolone and methylprednisolone acetate in rat plasma after intra-articular administration.

A sensitive and specific precursor ion scanning approach in liquid chromatography/electrospray ionization tandem mass spectrometry to detect methylprednisolone acetate and its metabolites in rat urine

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

Acrolein‐sequestering ability of endogenous dipeptides: characterization of carnosine and homocarnosine/acrolein adducts by electrospray ionization tandem mass spectrometry ⬇️

Actin Cys374 as a nucleophilic target of α,β-unsaturated aldehydes

Advanced glycation end products of beta2-microglobulin in uremic patients as determined by high resolution mass spectrometry

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation.

Advanced lipoxidation end products (ALEs) as RAGE binders: Mass spectrometric and computational studies to explain the reasons why

Albumin is the main nucleophilic target of human plasma: a protective role against pro-atherogenic electrophilic reactive carbonyl species?

An integrated high resolution mass spectrometric and informatics approach for the rapid identification of phenolics in plant extract.

Analysis of tiadenol in human plasma by capillary gas chromatography with electron capture detection

Anti-Elastase and Anti-Hyaluronidase Activities of Saponins and Sapogenins fromHedera helix, Aesculus hippocastanum, andRuscus aculeatus: Factors Contributing to their Efficacy in the Treatment of Venous Insufficiency

Antioxidant and photoprotective activity of a lipophilic extract containing neolignans from Krameria triandra roots.

Carboxylic metabolites of tiadenol as "proximate" inducers of hepatic peroxisomal beta-oxidation activity

Characterization of cisplatin-glutathione adducts by liquid chromatography-mass spectrometry. Evidence for their formation in vitro but not in vivo after concomitant administration of cisplatin and glutathione to rats anc cancer patients

Chemiluminescence and LC-MS/MS analyses for the study of nitric oxide release and distribution following oral administration of nitroaspirin (NCX 4016) in healthy volunteers

Covalent modification of actin by 4-hydroxy-trans-2-nonenal (HNE): LC-ESI-MS/MS evidence for Cys374 Michael adduction

Decrease in hepatic microsomal UDP-glucuronosyl-transferase activity in rats and cattle with fascioliasis: impaired in vitro glucuronidation of oxyclozanide

Decrease of the in vitro drug-metabolizing activity of the hepatic mixed function oxidase system in rats infected experimentally with Fasciola hepatica: pharmacological implications

Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146

Design, synthesis, ADME properties, and pharmacological activities of β-alanyl-D-histidine (D-carnosine) prodrugs with improved bioavailability

Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species

Determination of sunscreen agents by micellar electrokinetic chromatography

Detoxification of cytotoxic alpha,beta-unsaturated aldehydes by carnosine: characterization of conjugated adducts by electrospray ionization tandem mass spectrometry and detection by liquid chromatography/mass spectrometry in rat skeletal muscle.

Development and validation of a sensitive LC-MS/MS assay for the quantification of anserine in human plasma and urine and its application to pharmacokinetic study

Diet enriched with procyanidins enhances antioxidant activity and reduces myocardial post-ischaemic damage in rats

Edaravone inhibits protein carbonylation by a direct carbonyl-scavenging mechanism: focus on reactivity, selectivity, and reaction mechanisms

Effect of a standardized grape seed extract on low-density lipoprotein susceptibility to oxidation in heavy smokers.

Effect of the hypolipidemic drug bezafibrate on the hepatic mixed function oxidase system of the rat: heterogeneity monooxygenase responses.

Effects of UVB radiation on 4-hydroxy-2-trans-nonenal metabolism and toxicity in human keratinocytes.

Electron Spin Resonance and Chemiluminescence Analyses to Elucidate the Vasodilating Mechanism of Sodium Nitroprusside

Exploring the space of histidine containing dipeptides in search of novel efficient RCS sequestering agents

Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure.

Further studies on adriamycin induced in vitro lipid peroxidation

HNE Michael adducts to histidine and histidine-containing peptides as biomarkers of lipid-derived carbonyl stress in urines: LC-MS/MS profiling in Zucker obese rats.

Hemoglobin glutathionylation can occur through cysteine sulfenic acid intermediate: electrospray ionization LTQ-Orbitrap hybrid mass spectrometry studies.

Human serum albumin cysteinylation is increased in end stage renal disease patients and reduced by hemodialysis: mass spectrometry studies

Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement.

Identification of flavonoid metabolites after oral administration to rats of a Ginkgo biloba extract

Impaired in vitro metabolism of the flukicidal agent nitroxynil by hepatic microsomal cytochrome P-450 in bovine fascioliasis

In vitro biotransformation of pyrazinamide by rat liver: identification of a new metabolite.

In vitro metabolism of a nitroderivative of acetylsalicylic acid (NCX4016) by rat liver: LC and LC-MS studies

Intervention strategies to inhibit protein carbonylation by lipoxidation-derived reactive carbonyls.

Intravenous Infusion of Nitric Oxide in Experimental Pulmonary Hypertension: Biotransformation and Haemodynamics

LC-ESI-MS/MS determination of 4-hydroxy-trans-2-nonenal Michael adducts with cysteine and histidine-containing peptides as early markers of oxidative stress in excitable tissues.

Mass spectrometric approaches for the identification and quantification of reactive carbonyl species protein adducts

Mass spectrometric characterization and HPLC determination of the main urinary metabolites of nimesulide in man

Mass spectrometric characterization of covalent modification of human serum albumin by 4-hydroxy-trans-2-nonenal

Mass spectrometric strategies for the identification and characterization of human serum albumin covalently adducted by amoxicillin: ex vivo studies

Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins.

Metabolic profile of NO-flurbiprofen (HCT1026) in rat brain and plasma: a LC-MS study.

Methylprednisolone‐loaded PLGA microspheres: A new formulation for sustained release via intra‐articular administration. A comparison study with methylprednisolone acetate in rats

Nitric oxide release and distribution following oral and intraperitoneal administration of nitroaspirin (NCX 4016) in the rat

Nitrosylhemoglobin as a Potential Bioactive Storage form of Nitric Oxide (NO)

Nitrosylhemoglobin formation after infusion of NO solutions: ESR studies in pigs.

Nitrosylhemoglobin, an unequivocal index of nitric oxide release from nitroaspirin: in vitro and in vivo studies in the rat by ESR spectroscopy

Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds

Panax ginseng Administration in the Rat Prevents Myocardial Ischemia-Reperfusion Damage Induced by Hyperbaric Oxygen: Evidence for an Antioxidant Intervention

Preservation of endothelium nitric oxide release by pulsatile flow cardiopulmonary bypass when compared with continuous flow

Preservation of endothelium nitric oxide release during beating heart surgery with respect to continuous flow cardiopulmonary bypass

Procyanidins from grape seeds protect endothelial cells from peroxynitrite damage and enhance endothelium-dependent relaxation in human artery: new evidences for cardio-protection ⬇️

Profiling histidine dipeptides in plasma and urine after ingesting beef, chicken or chicken broth in humans.

Profiling histidine-containing dipeptides in rat tissues by liquid chromatography/electrospray ionization tandem mass spectrometry.

Protein carbonylation.

Protein carbonylation: 2,4-dinitrophenylhydrazine reacts with both aldehydes/ketones and sulfenic acids.

Protein haptenation by amoxicillin: High resolution mass spectrometry analysis and identification of target proteins in serum

Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents.

Rapid analysis of alpha-hederin in a crude plant extract by collisional mass spectrometry (CAD MIKES)

Scavenging of free radicals by tenoxicam: a participating mechanism in the antirheumatic/antiinflammatory efficacy of the drug

Screening of fibrillogenesis inhibitors of β2-microglobulin: integrated strategies by mass spectrometry capillary electrophoresis and in silico simulations

Searching for allergens in maize kernels via proteomic tools.

Stressed degradation studies of domiphen bromide by LC-ESI-MS/MS identify a novel promising antimicrobial agent

The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats

The inhibitory effect of pyrazinamide on microsomal monooxygenase activities is related to the binding to reduced cytochrome P-450