Search filters

List of works by Martin A Schwartz

A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells.

scientific article published in September 1993

A circular dichroism study of the effects of a hemolytic toxin from gymnodinium breve, the Florida red tide organism, on human erythrocyte membranes

article published in 1976

A dominant-negative p65 PAK peptide inhibits angiogenesis.

scientific article

A fluorescence resonance energy transfer activation sensor for Arf6

scientific article

A new radioactive cross-linking reagent for studying the interactions of proteins.

scientific article published on March 1982

A novel in vitro flow system for changing flow direction on endothelial cells.

scientific article

A role for p21-activated kinase in endothelial cell migration.

scientific article

Actin flow-dependent and -independent force transmission through integrins

scientific article published on 01 December 2020

Activation of Rac and Cdc42 by integrins mediates cell spreading

scientific article (publication date: July 1998)

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.

scientific article

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

scientific article

Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

scientific article published on 14 February 2018

Adhesion is required for protein kinase C-dependent activation of the Na+/H+ antiporter by platelet-derived growth factor ⬇️

scientific article published on July 1, 1992

Adhesion to the extracellular matrix regulates the coupling of the small GTPase Rac to its effector PAK.

scientific article

Alpha v integrins mediate the rise in intracellular calcium in endothelial cells on fibronectin even though they play a minor role in adhesion

scientific article published in Journal of Biological Chemistry

An activated Rac mutant functions as a dominant negative for membrane ruffling ⬇️

scientific article published on August 6, 1998

Arf6 and microtubules in adhesion-dependent trafficking of lipid rafts.

scientific article

Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation

scientific article

Binding of actin to liver cell membranes: the state of membrane-bound actin ⬇️

scientific article published on March 1, 1991

Biomechanics of vascular mechanosensation and remodeling

scientific article

Cadherin adhesion, tissue tension, and noncanonical Wnt signaling regulate fibronectin matrix organization

scientific article

Cell adhesion receptors in mechanotransduction

scientific article

Cell adhesion: integrating cytoskeletal dynamics and cellular tension ⬇️

scientific article published on September 1, 2010

Cell biology. Dysfunctional mechanosensing in aneurysms

scientific article published on May 2014

Cell biology. The force is with us.

scientific article

Cell migration: Towards the void

scientific article published in September 2013

Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis

scientific article

Coordinate signaling by integrins and receptor tyrosine kinases in the regulation of G1 phase cell-cycle progression.

scientific article

Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism

scientific article

Deconstructing Dimensionality

scientific article published in Science

Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia

scientific article published on 19 September 2016

Determination of GTP loading on Rho

scientific article published on 01 January 2000

Differing structural requirements for GTPase-activating protein responsiveness and NADPH oxidase activation by Rac.

scientific article published on September 1994

Dynamic molecular processes mediate cellular mechanotransduction

scientific article published on 20 July 2011

Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling.

scientific article

Electrochemically Derived Gradients of the Extracellular Matrix Protein Fibronectin on Gold

Endogenous RhoG is dispensable for integrin-mediated cell spreading but contributes to Rac-independent migration.

scientific article

Filamin A mediates isotropic distribution of applied force across the actin network

scientific article published on 17 July 2019

Flow-dependent cellular mechanotransduction in atherosclerosis

scientific article

Focal adhesion kinase modulates activation of NF-kappaB by flow in endothelial cells.

scientific article

Force regulated conformational change of integrin αVβ3.

scientific article published on 13 July 2016

Function of the N-terminus of zizimin1: autoinhibition and membrane targeting.

scientific article

Growth factor activation of MAP kinase requires cell adhesion.

scientific article

How actin binds and assembles onto plasma membranes from Dictyostelium discoideum.

scientific article

Hydrogen atom exchange between nitroxides and hydroxylamines

scientific article published in 1979

Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration

scientific article (publication date: December 2001)

Inhibition of cell cycle progression by the alternatively spliced integrin beta 1C

scientific article

Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin alpha 5 beta 1, independent of cell shape ⬇️

scientific article published on September 1, 1991

Integrin activation and matrix binding mediate cellular responses to mechanical stretch

scientific article

Integrin agonists as adjuvants in chemotherapy for melanoma.

scientific article

Integrin beta 1- and beta 3-mediated endothelial cell migration is triggered through distinct signaling mechanisms.

scientific article published on April 1993

Integrin signaling revisited ⬇️

scientific article published on December 1, 2001

Integrin signaling: roles for the cytoplasmic tails of alpha IIb beta 3 in the tyrosine phosphorylation of pp125FAK

scientific article published on 01 December 1995

Integrin signalling in directed cell migration.

scientific article

Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis

scientific article published on 13 August 2019

Integrin-dependent actomyosin contraction regulates epithelial cell scattering.

scientific article

Integrin-dependent tyrosine phosphorylation and growth regulation by Vav

scientific article published on 01 January 1999

Integrin-mediated adhesion regulates membrane order

scientific article

Integrin-mediated adhesions in regulation of cellular senescence

scientific article published on 06 May 2020

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

scholarly article

Integrins and extracellular matrix in mechanotransduction

scientific article

Integrins in mechanotransduction

scientific article (publication date: 26 March 2004)

Integrins in mechanotransduction

scientific article published on 21 June 2013

Integrins regulate the association and phosphorylation of paxillin by c-Abl

scientific article

Integrins, adhesion and apoptosis.

scientific article published in April 1997

Integrins, oncogenes, and anchorage independence.

scientific article

Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling

scientific article published on 05 September 2016

Involvement of the small GTPase rho in integrin-mediated activation of mitogen-activated protein kinase.

scientific article published on September 1996

JNK2 Promotes Endothelial Cell Alignment under Flow ⬇️

scientific article published on August 31, 2011

KLF4 is a key determinant in the development and progression of cerebral cavernous malformations

scientific article

Kinetics of antibody association with spin-label haptens on membrane surfaces

Lessons from the endothelial junctional mechanosensory complex.

scientific article published on 03 January 2012

Light-triggered myosin activation for probing dynamic cellular processes.

scientific article

Live imaging molecular changes in junctional tension upon VE-cadherin in zebrafish

scientific article published on 10 November 2017

Localized Rac activation dynamics visualized in living cells

scientific article

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

scientific article published on 16 May 2003

Lymphatics thrive on stress: mechanical force in lymphatic development ⬇️

scientific article published on February 15, 2012

MKL1-actin pathway restricts chromatin accessibility and prevents mature pluripotency activation

scientific article published on 12 April 2019

Mapping in vivo associations of cytoplasmic proteins with integrin beta 1 cytoplasmic domain mutants.

scientific article published on February 1995

Matrix and meaning

scientific article published in January 2002

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis.

scientific article

Matrix-specific suppression of integrin activation in shear stress signaling.

scientific article

Mechanical stress-activated integrin α5β1 induces opening of connexin 43 hemichannels.

scientific article

Mechanisms of mechanotransduction.

scientific article

MicroRNA-dependent regulation of biomechanical genes establishes tissue stiffness homeostasis

scientific article published on 11 February 2019

Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl.

scientific article

Mutational analysis of cell cycle inhibition by integrin beta1C.

scientific article published on March 1999

Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases.

scientific article

N-cadherin regulates spatially polarized signals through distinct p120ctn and β-catenin-dependent signalling pathways.

scientific article

Neuropilin-1 stimulates tumor growth by increasing fibronectin fibril assembly in the tumor microenvironment

scientific article

Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.

scientific article

Physical association of the small GTPase Rho with a 68-kDa phosphatidylinositol 4-phosphate 5-kinase in Swiss 3T3 cells.

scientific article published on March 1996

Putting the squeeze on mechanotransduction

scientific article

Registration of the extracellular matrix components constituting the fibroblastic focus in idiopathic pulmonary fibrosis

scientific article published on 10 January 2019

Regulation of Rac1 translocation and activation by membrane domains and their boundaries

scientific article

Regulation of inositol lipid kinases by Rho and Rac.

scientific article published on February 1998

Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of RhoGTPases.

scientific article

Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.

scientific article

Rho proteins in cell migration and metastasis.

scientific article

Role of Rho and myosin phosphorylation in actin stress fiber assembly in mesangial cells ⬇️

scientific article published on August 1, 1997

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

scientific article published on 15 December 2017

Signaling by integrins: implications for tumorigenesis

scientific article published on 01 April 1993

Signaling networks linking integrins and rho family GTPases.

scientific article

Spreading of human endothelial cells on fibronectin or vitronectin triggers elevation of intracellular free calcium ⬇️

scientific article published on February 1, 1993

Src and Caveolin-1 Reciprocally Regulate Metastasis via a Common Downstream Signaling Pathway in Bladder Cancer ⬇️

scientific article published on December 10, 2010

Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function.

scientific article

Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42

scientific article

Studying the Cytoskeleton by Label Transfer Crosslinking: Uses and Limitations

Super-resolution microscopy: a new dimension in focal adhesions.

scientific article

Suppression of RhoG activity is mediated by a syndecan 4-synectin-RhoGDI1 complex and is reversed by PKCalpha in a Rac1 activation pathway.

scientific article

Surface areas of lipid membranes

article by M A Schwartz & H M McConnell published 7 March 1978 in Biochemistry

Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling

scientific article

Talin as a mechanosensitive signaling hub

scientific article published on 25 September 2018

The Regulation of Growth and Intracellular Signaling by Integrins

article

The UIP/IPF fibroblastic focus is a collagen biosynthesis factory embedded in a distinct extracellular matrix

scientific article published in 2022

The importance of stupidity in scientific research

scientific article

The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.

scientific article

The role of cellular adaptation to mechanical forces in atherosclerosis

scientific article

The role of p21-activated kinase in the initiation of atherosclerosis.

scientific article

Timing of cyclin D1 expression within G1 phase is controlled by Rho ⬇️

scientific article published on November 1, 2001

Transmembrane signalling by integrins

scientific article published on 01 October 1992

VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN.

scientific article published on 10 July 2017

VE-Cadherin Phosphorylation Regulates Endothelial Fluid Shear Stress Responses through the Polarity Protein LGN.

scientific article published in September 2017

VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.

scientific article published on 3 December 2004

Vascular remodeling is governed by a VEGFR3-dependent fluid shear stress set point

scientific article

Vinculin and the mechanical response of adherent fibroblasts to matrix deformation

scientific article published in Scientific Reports

hMENA isoforms impact NSCLC patient outcome through fibronectin/β1 integrin axis

scientific article published on 15 June 2018

p21-Activated kinase 4 promotes prostate cancer progression through CREB

scientific article

p21-activated kinase regulates endothelial permeability through modulation of contractility.

scientific article

p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow.

scientific article

Paulina is supported by:

About Paulina

Help