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List of works by Federica Gilardi

A multiplicity of factors contributes to selective RNA polymerase III occupancy of a subset of RNA polymerase III genes in mouse liver

scientific journal article

Anti-adipogenic signals at the onset of obesity-related inflammation in white adipose tissue

scientific article published on 11 March 2020

Bile acids and gene regulation: from nuclear receptors to chromatin.

scientific article published on May 2008

Bile acids and their signaling pathways: eclectic regulators of diverse cellular functions.

scientific article published on October 2007

Chlamydia pneumoniae acute liver infection affects hepatic cholesterol and triglyceride metabolism in mice.

scientific article published on 03 June 2015

Crystal structure of the peroxisome proliferator-activated receptor gamma (PPARgamma) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic pocket could be exploited for drug design

scientific article

DBnorm as an R package for the comparison and selection of appropriate statistical methods for batch effect correction in metabolomic studies

scientific article published on 11 March 2021

Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion

scientific article published on 28 September 2017

Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175.

scientific article

Expression of sterol 27-hydroxylase in glial cells and its regulation by liver X receptor signaling.

scientific article published on 7 August 2009

From chronic overnutrition to metaflammation and insulin resistance: adipose tissue and liver contributions

scientific article published on 5 July 2017

Genome-wide RNA polymerase II profiles and RNA accumulation reveal kinetics of transcription and associated epigenetic changes during diurnal cycles

scientific article (publication date: 2012)

Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals

scientific article

HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning

scientific article published on 21 July 2017

Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.

scientific article published on 28 February 2018

Inflammatory serum proteome pattern in mice fed a high-fat diet.

scientific article published on 6 December 2012

Inhibition of class I histone deacetylases unveils a mitochondrial signature and enhances oxidative metabolism in skeletal muscle and adipose tissue

scientific article published on 15 October 2012

Insights in the regulation of cholesterol 7alpha-hydroxylase gene reveal a target for modulating bile acid synthesis.

scientific article

LT175 is a novel PPARα/γ ligand with potent insulin-sensitizing effects and reduced adipogenic properties.

scientific article published on 22 January 2014

LXR (liver X receptor) and HNF-4 (hepatocyte nuclear factor-4): key regulators in reverse cholesterol transport.

scientific article published on February 2004

Lack of Adipocytes Alters Hematopoiesis in Lipodystrophic Mice

scientific article published on 13 November 2018

Linking epigenetics to lipid metabolism: focus on histone deacetylases.

scientific article

Molecular determinants for nuclear receptors selectivity: chemometric analysis, dockings and site-directed mutagenesis of dual peroxisome proliferator-activated receptors α/γ agonists.

scientific article published on 24 February 2013

Nephropathy in Pparg-null mice highlights PPARγ systemic activities in metabolism and in the immune system

scientific article

PPARγ Controls Ectopic Adipogenesis and Cross-Talks with Myogenesis During Skeletal Muscle Regeneration

scientific article published on 13 July 2018

RXRs: collegial partners

scientific article published on January 2014

Renal mineralocorticoid receptor expression is reduced in lipoatrophy

scientific article published on 18 January 2019

SOCS3 transactivation by PPARγ prevents IL-17-driven cancer growth

scientific article published on 25 April 2013

Site-directed mutagenesis to study the role of specific amino acids in the ligand binding domain of PPARs.

scientific article

Sterol-protein interactions in cholesterol and bile acid synthesis.

scientific article published on January 2010

Structural insight into peroxisome proliferator-activated receptor gamma binding of two ureidofibrate-like enantiomers by molecular dynamics, cofactor interaction analysis, and site-directed mutagenesis

scientific article published on June 2010

Synthesis, characterization and biological evaluation of ureidofibrate-like derivatives endowed with peroxisome proliferator-activated receptor activity

scientific article

Systemic PPARγ deletion in mice provokes lipoatrophy, organomegaly, severe type 2 diabetes and metabolic inflexibility

scientific article published on 13 March 2019

The pharmacological exploitation of cholesterol 7alpha-hydroxylase, the key enzyme in bile acid synthesis: from binding resins to chromatin remodelling to reduce plasma cholesterol.

scientific article published on 07 September 2007

Transcriptional regulatory logic of the diurnal cycle in the mouse liver

scientific article

When food meets man: the contribution of epigenetics to health.

scientific article published on 25 May 2010

Will Widespread Synthetic Opioid Consumption Induce Epigenetic Consequences in Future Generations?

scholarly article by Federica Gilardi et al published 2018 in Frontiers in Pharmacology

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