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List of works by Crescenzo D'Alterio

A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors

scientific article

A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion

scientific article published on 27 October 2015

A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration

scientific article published on 23 April 2009

A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients

scientific article published on 10 January 2014

COX-2 expression positively correlates with PD-L1 expression in human melanoma cells

scientific article published on 23 February 2017

CXCL12 loaded-dermal filler captures CXCR4 expressing melanoma circulating tumor cells

scientific article published on 22 July 2019

CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not

scientific article published on 3 November 2014

CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients

scientific article published on 29 November 2016

CXCR4-antagonist Peptide R-liposomes for combined therapy against lung metastasis.

scientific article published on 17 March 2016

CXCR4/CXCL12/CXCR7 axis is functional in neuroendocrine tumors and signals on mTOR.

scientific article published on 26 February 2016

Cetuximab, irinotecan and fluorouracile in fiRst-line treatment of immunologically-selected advanced colorectal cancer patients: the CIFRA study protocol

scientific article published on 09 September 2019

Concomitant CXCR4 and CXCR7 Expression Predicts Poor Prognosis in Renal Cancer

scientific article published on 01 November 2010

Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists

scientific article

High CXCR4 expression correlates with sunitinib poor response in metastatic renal cancer.

scientific article

High-Frequency Ultrasound-Guided Injection for the Generation of a Novel Orthotopic Mouse Model of Human Thyroid Carcinoma.

scientific article published on 4 February 2016

Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer

scientific article

Inhibition of stromal CXCR4 impairs development of lung metastases.

scientific article

New Insights on the Emerging Genomic Landscape of CXCR4 in Cancer: A Lesson from WHIM

scientific article published on 03 April 2020

Paradoxical effects of chemotherapy on tumor relapse and metastasis promotion

scientific article published on 24 August 2019

Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients.

scientific article published on April 2015

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

scientific article

Prospective Evaluation of Cetuximab-Mediated Antibody-Dependent Cell Cytotoxicity in Metastatic Colorectal Cancer Patients Predicts Treatment Efficacy

scientific article published on 27 January 2016

Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1

scientific article published on 28 October 2019

Targeting CXCR4 reverts the suppressive activity of T-regulatory cells in renal cancer.

scientific article published on 19 August 2017

Variability in Immunohistochemical Detection of Programmed Death Ligand 1 (PD-L1) in Cancer Tissue Types.

scientific article published on 21 May 2016