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List of works by Paolo Mellini

1,4-Dihydropyridines Active on the SIRT1/AMPK Pathway Ameliorate Skin Repair and Mitochondrial Function and Exhibit Inhibition of Proliferation in Cancer Cells

scientific article published on 21 December 2015

Carprofen analogues as sirtuin inhibitors: enzyme and cellular studies

scientific article published on November 2012

Discovery of salermide-related sirtuin inhibitors: binding mode studies and antiproliferative effects in cancer cells including cancer stem cells

scientific article published on 12 December 2012

Efficient Synthesis of 3,5-Dicarbamoyl-1,4-dihydropyridines from Pyridinium Salts: Key Molecules in Understanding NAD(P)+/NAD(P)H Pathways

Facile and Efficient Synthesis of 4-Alkyl Derivatives of 3-Carbamoyl- and 3,5-Dicarbamoylpyridines as Nicotinamide Mimetics

Identification of SNAIL1 Peptide-Based Irreversible Lysine-Specific Demethylase 1-Selective Inactivators

scientific article published on 23 December 2015

Potent mechanism-based sirtuin-2-selective inhibition by an in situ-generated occupant of the substrate-binding site, "selectivity pocket" and NAD+-binding site.

scientific article published on 21 July 2017

Quantitative insights for the design of substrate-based SIRT1 inhibitors

scientific article published on 18 April 2014

Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells

scientific article

Sirtuin modulators: an updated patent review (2012 - 2014).

scientific article

Studying SIRT6 regulation using H3K56 based substrate and small molecules

scientific article published on 06 July 2014

Synthesis and antifungal activity of a new series of 2-(1H-imidazol-1-yl)-1-phenylethanol derivatives

scientific article published on 26 January 2012

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