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List of works by William Blalock

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.

scientific article

A novel human fibronectin cryptic sequence unmasked by the insertion of the angiogenesis-associated extra type III domain B.

scientific article published in August 2009

A rapid standardized quantitative microfluidic system approach for evaluating human tear proteins.

scientific article

A role for PKR in hematologic malignancies.

scientific article published in June 2010

A role for PLCβ1 in myotonic dystrophies type 1 and 2

article

Ability of the activated PI3K/Akt oncoproteins to synergize with MEK1 and induce cell cycle progression and abrogate the cytokine-dependence of hematopoietic cells.

scientific article published on April 2004

BMP-2 Induced Expression of PLCβ1 That is a Positive Regulator of Osteoblast Differentiation.

scientific article published on 27 July 2015

Cell Cycle Arrest and Apoptosis Induced by Kinamycin F in Human Osteosarcoma Cells.

scientific article

Ceramide regulates protein synthesis by a novel mechanism involving the cellular PKR activator RAX.

scientific article

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

scientific article published on June 2000

Ectopic Expression of Ankrd2 Affects Proliferation, Motility and Clonogenic Potential of Human Osteosarcoma Cells

scientific article published on 06 January 2021

Effects of deregulated RAF and MEK1 expression on the cytokine-dependency of hematopoietic cells.

scientific article

Effects of deregulated Raf activation on integrin, cytokine-receptor expression and the induction of apoptosis in hematopoietic cells

scientific article published on 01 November 2000

Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

scientific article published in April 2003

Elucidation of signal transduction pathways by retroviral infection of cells with modified oncogenes.

scientific article published on January 2003

Elucidation of signal transduction pathways by transfection of cells with modified oncogenes

scientific article published on 01 January 2003

Enhanced ability of daniplestim and myelopoietin-1 to suppress apoptosis in human hematopoietic cells

scientific article published on 01 August 2001

Enhanced ability of the progenipoietin-1 to suppress apoptosis in human hematopoietic cells.

scientific article published on October 2002

Expression of the double-stranded RNA-dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion

scientific article published on 25 June 2019

Fibroblastic, hematopoietic, and hormone responsive epithelial cell lines and culture conditions for elucidation of signal transduction and drug resistance pathways by gene transfer.

scientific article

Identification of the PKR nuclear interactome reveals roles in ribosome biogenesis, mRNA processing and cell division

scientific article published on August 2014

Interactions between the PI3K and Raf signaling pathways can result in the transformation of hematopoietic cells

scientific article published on 01 January 2001

Intolerant contact lens wearers exhibit ocular surface impairment despite 3 months wear discontinuation.

scientific article

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

scientific article

MiRNA-210: A Current Overview.

scientific article published in December 2017

Multiple forms of PKR present in the nuclei of acute leukemia cells represent an active kinase that is responsive to stress.

scientific article published on 12 November 2010

Nuclear PI-PLCβ1: an appraisal on targets and pathology

scientific article

Oncogenic effects of overexpression of the interleukin-3 receptor on hematopoietic cells

scientific article published on 01 March 1996

PI-PLCbeta-1 and activated Akt levels are linked to azacitidine responsiveness in high-risk myelodysplastic syndromes

scientific article published on 12 July 2007

PI-PLCβ1b affects Akt activation, cyclin E expression, and caspase cleavage, promoting cell survival in pro-B-lymphoblastic cells exposed to oxidative stress

scientific article

PKR activity is required for acute leukemic cell maintenance and growth: a role for PKR-mediated phosphatase activity to regulate GSK-3 phosphorylation

scientific article

PKR is activated in MDS patients and its subcellular localization depends on disease severity

scientific article published on 22 May 2008

PLC-beta 1 regulates the expression of miR-210 during mithramycin-mediated erythroid differentiation in K562 cells

scientific article

PLCβ1a and PLCβ1b selective regulation and cyclin D3 modulation reduced by kinamycin F during k562 cell differentiation.

scientific article published on March 2015

Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein.

scientific article published on 09 May 2013

Proapoptotic activity and chemosensitizing effect of the novel Akt inhibitor (2S)-1-(1H-Indol-3-yl)-3-[5-(3-methyl-2H-indazol-5-yl)pyridin-3-yl]oxypropan2-amine (A443654) in T-cell acute lymphoblastic leukemia

scientific article published on 24 June 2008

Prohibitin 2 represents a novel nuclear AKT substrate during all-trans retinoic acid-induced differentiation of acute promyelocytic leukemia cells.

scientific article published on 12 February 2014

Prohibitin 2: At a communications crossroads

scientific article

RAX is required for fly neuronal development and mouse embryogenesis.

scientific article published on 26 June 2008

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

scientific article

Regulation of cell cycle progression and apoptosis by the Ras/Raf/MEK/ERK pathway (Review).

scientific article

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

scientific article published in June 2003

Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition

scientific article

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

scientific article

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

scientific journal article

Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf.

scientific article published in January 2001

Synergy between Raf and BCL2 in abrogating the cytokine dependency of hematopoietic cells.

scientific article published on June 2000

Therapeutic potential of nvp-bkm120 in human osteosarcomas cells

scientific article published on 07 December 2018

eEF1A phosphorylation in the nucleus of insulin-stimulated C2C12 myoblasts: Ser⁵³ is a novel substrate for protein kinase C βI.

scientific article published on 5 October 2010

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