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List of works by Brent A French

152 Gadolinium-labeled liposomes as a DENSE-compatible, positive MRI contrast agent for serially assessing macrophage activity and regional contractile function in the murine heart after myocardial infarction

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2091 Manganese enhanced mri demonstrates a predominant role for nNOS, not eNOS, in modulating L-Type calcium channel flux in the heart

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2093 CMR reveals that cardiac-specific overexpression of the inducible form of nitric oxide synthase induces Left Ventricular Hypertrophy in wild-type mice after AAV-Mediated direct gene transfer

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3D perfusion mapping in post-infarct mice using myocardial contrast echocardiography

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A Nonpeptide Angiotensin II Type 2 Receptor Agonist Does Not Attenuate Postmyocardial Infarction Left Ventricular Remodeling in Mice

scientific article published on April 1, 2012

A novel cardiac muscle-derived biomaterial reduces dyskinesia and postinfarct left ventricular remodeling in a mouse model of myocardial infarction

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A practical approach to remote ischemic preconditioning and ischemic preconditioning against myocardial ischemia/reperfusion injury

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A single direct injection into the left ventricular wall of an adeno‐associated virus 9 (AAV9) vector expressing extracellular superoxide dismutase from the cardiac troponin‐T promoter protects mice against myocardial infarction

scientific article published on June 1, 2011

AAV9 and Cre: a one-two punch for a quick cardiac knockout

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Activated platelets contribute importantly to myocardial reperfusion injury

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Acute cardiovascular protective effects of corticosteroids are mediated by non-transcriptional activation of endothelial nitric oxide synthase

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Acute hyperglycemia abolishes ischemic preconditioning by inhibiting Akt phosphorylation: normalizing blood glucose before ischemia restores ischemic preconditioning

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Acute hyperglycemia enhances oxidative stress and exacerbates myocardial infarction by activating nicotinamide adenine dinucleotide phosphate oxidase during reperfusion

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Acute hyperglycemic exacerbation of lung ischemia-reperfusion injury is mediated by receptor for advanced glycation end-products signaling

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Adeno-associated virus serotype 9 administered systemically after reperfusion preferentially targets cardiomyocytes in the infarct border zone with pharmacodynamics suitable for the attenuation of left ventricular remodeling

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Adeno-associated virus serotype 9-mediated overexpression of extracellular superoxide dismutase improves recovery from surgical hind-limb ischemia in BALB/c mice

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Adenosine 2B Receptor Activation Reduces Myocardial Reperfusion Injury by Promoting Anti-Inflammatory Macrophages Differentiation via PI3K/Akt Pathway

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Alterations to myofibrillar protein function in nonischemic regions of the heart early after myocardial infarction

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An ultrasound-driven kinematic model for deformation of the infarcted mouse left ventricle incorporating a near-incompressibility constraint

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Angiotensin II type 2 receptor overexpression preserves left ventricular function after myocardial infarction

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Arterial spin labeling CMR quantifies increased perfusion in hearts of mice treated with cardioprotective, AAV9-mediated EcSOD gene therapy prior to myocardial infarction

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Atorvastatin at reperfusion reduces myocardial infarct size in mice by activating eNOS in bone marrow-derived cells

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Black blood gradient echo cine magnetic resonance imaging of the mouse heart

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Borderzone contractile dysfunction is transiently attenuated and left ventricular structural remodeling is markedly reduced following reperfused myocardial infarction in inducible nitric oxide synthase knockout mice

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Cardiac overexpression of A1-adenosine receptor protects intact mice against myocardial infarction

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Cardiac-selective expression of extracellular superoxide dismutase after systemic injection of adeno-associated virus 9 protects the heart against post-myocardial infarction left ventricular remodeling

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Chemical Endoplasmic Reticulum Chaperone Alleviates Doxorubicin-Induced Cardiac Dysfunction

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Complementary displacement-encoded MRI for contrast-enhanced infarct detection and quantification of myocardial function in mice

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Comprehensive Cardiovascular magnetic resonance of myocardial mechanics in mice using three-dimensional cine DENSE

scientific article published on December 30, 2011

Comprehensive assessment of myocardial mechanics in mice using 3D cine DENSE.

scientific article published on 2 February 2011

Comprehensive assessment of myocardial strain in post-infarct mice using 3D Cine DENSE

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Detection of increased coronary microvascular permeability with MRI T1 mapping and gadolinium-labeled albumin.

scientific article published on 27 January 2016

Development of target-specific liposomes for delivering small molecule drugs after reperfused myocardial infarction

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Displacement-encoded and manganese-enhanced cardiac MRI reveal that nNOS, not eNOS, plays a dominant role in modulating contraction and calcium influx in the mammalian heart

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Does a selective non-peptide angiotensin II type 2 receptor agonist reduce post-infarction left ventricular remodeling?

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Early assessment of pulmonary inflammation by 19F MRI in vivo

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Effect of modulating cardiac A1 adenosine receptor expression on protection with ischemic preconditioning

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Evaluation of pharmacokinetic and pharmacodynamic profiles of liposomes for the cell type-specific delivery of small molecule drugs

scientific article published on 25 July 2017

Extracellular superoxide dismutase ameliorates skeletal muscle abnormalities, cachexia, and exercise intolerance in mice with congestive heart failure

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Gene expression profile of mouse myocardium with transgenic overexpression of A1 adenosine receptors

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Heart Rate Reduction With Ivabradine Protects Against Left Ventricular Remodeling by Attenuating Infarct Expansion and Preserving Remote-Zone Contractile Function and Synchrony in a Mouse Model of Reperfused Myocardial Infarction

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High frequency ultrasound imaging detects cardiac dyssynchrony in noninfarcted regions of the murine left ventricle late after reperfused myocardial infarction

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High-resolution myocardial perfusion imaging in mice with high-frequency echocardiographic detection of a depot contrast agent

scientific article published in February 2007

Images in cardiovascular medicine. Serial multimodality assessment of myocardial infarction in mice using magnetic resonance imaging and micro-positron emission tomography provides complementary information on the progression of scar formation

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Impact of dietary nitrate on age-related diastolic dysfunction

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Improved arterial spin labeling after myocardial infarction in mice using cardiac and respiratory gated look-locker imaging with fuzzy C-means clustering

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Infarct-sparing effect of A2A-adenosine receptor activation is due primarily to its action on lymphocytes

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Interaction between AT1 and AT2 receptors during postinfarction left ventricular remodeling

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Interaction between bradykinin subtype 2 and angiotensin II type 2 receptors during post-MI left ventricular remodeling

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Left ventricular remodeling subsequent to reperfused myocardial infarction: evaluation of a rat model using cardiac magnetic resonance imaging

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MR tagging early after myocardial infarction in mice demonstrates contractile dysfunction in adjacent and remote regions

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Measurement of myocardial mechanics in mice before and after infarction using multislice displacement-encoded MRI with 3D motion encoding

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Mechanisms of Post-Infarct Left Ventricular Remodeling

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Monocyte and/or macrophage infiltration of heart after myocardial infarction: MR imaging by using T1-shortening liposomes

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Multi-parameter in vivo cardiac magnetic resonance imaging demonstrates normal perfusion reserve despite severely attenuated beta-adrenergic functional response in neuronal nitric oxide synthase knockout mice

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Multimodality cardiovascular molecular imaging, Part II

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Multimodality imaging of myocardial injury and remodeling

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Myocardial infarct-sparing effect of adenosine A2A receptor activation is due to its action on CD4+ T lymphocytes

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Neuraminidase Mediated Desialylation Augments AAV9 Mediated Gene Expression in Skeletal Muscle

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Nitric oxide mediates benefits of angiotensin II type 2 receptor overexpression during post-infarct remodeling

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Noninvasive tracking of cardiac embryonic stem cells in vivo using magnetic resonance imaging techniques

scientific article published on 9 August 2007

Pharmacologic immunomodulation via adenosine 2a receptor stimulation improves LV remodeling and systolic strain in regions adjacent to the infarct as assessed by cardiac MRI.

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Plectin-1 Targeted AAV Vector for the Molecular Imaging of Pancreatic Cancer

scientific article published on April 18, 2013

Postinfarction myocardial scarring in mice: molecular MR imaging with use of a collagen-targeting contrast agent.

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Quantification and MRI validation of regional contractile dysfunction in mice post myocardial infarction using high resolution ultrasound

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Quantitative first-pass MRI measures increased myocardial perfusion after vasodilation in mice.

scientific article published in February 2012

Quantitative first-pass perfusion MRI of the mouse heart

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Repeatability and variability of myocardial perfusion imaging techniques in mice: Comparison of arterial spin labeling and first-pass contrast-enhanced MRI.

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Reperfused myocardial infarction in mice: 3D mapping of late gadolinium enhancement and strain

scientific article published in January 2006

Serial MRI evaluation of cardiac structure and function in mice after reperfused myocardial infarction

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Serial Ultrasound Evaluation of Intramyocardial Strain After Reperfused Myocardial Infarction Reveals That Remote Zone Dyssynchrony Develops in Concert With Left Ventricular Remodeling

scientific article published on June 2, 2011

Simultaneous evaluation of infarct size and cardiac function in intact mice by contrast-enhanced cardiac magnetic resonance imaging reveals contractile dysfunction in noninfarcted regions early after myocardial infarction

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Splenic leukocytes mediate the hyperglycemic exacerbation of myocardial infarct size in mice

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Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle

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Systemic delivery of shRNA by AAV9 provides highly efficient knockdown of ubiquitously expressed GFP in mouse heart, but not liver

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T2-weighted MRI pulse sequences for imaging post-infarct edema in mice: comparison of spin echo and T2 preparation approaches

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Targeted tissue transfection with ultrasound destruction of plasmid-bearing cationic microbubbles

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Targeting of adenosine receptors in ischemia-reperfusion injury

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The angiotensin II type 2 receptor and improved adjacent region function post-MI.

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The infarct-sparing effect of IB-MECA against myocardial ischemia/reperfusion injury in mice is mediated by sequential activation of adenosine A3 and A 2A receptors

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The myocardial infarct-exacerbating effect of cell-free DNA is mediated by the high-mobility group box 1-receptor for advanced glycation end products-Toll-like receptor 9 pathway

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The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE.

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Therapeutic Efficacy of Alpha-Lipoic Acid against Acute Myocardial Infarction and Chronic Left Ventricular Remodeling in Mice

scientific article published on 07 January 2020

Timing of adenosine 2A receptor stimulation relative to reperfusion has differential effects on infarct size and cardiac function as assessed in mice by MRI

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Topoisomerase Inhibition Accelerates Gene Expression after Adeno-associated Virus-mediated Gene Transfer to the Mammalian Heart

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Topoisomerase inhibition accelerates gene expression after adeno-associated virus-mediated gene transfer to the mammalian heart

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T₂ -weighted MRI of post-infarct myocardial edema in mice

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Whole-heart T2-weighted (T2w) sequence for imaging post-infarct edematous area at risk (AR) in mice

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