List of works - Jarek Meller

A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model

scientific article published on 17 May 2017

ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children

scientific article published on 26 January 2016

Accurate prediction of solvent accessibility using neural networks-based regression.

scientific article

Analysis of current antifungal agents and their targets within the Pneumocystis carinii genome.

scientific article

Building and assessing atomic models of proteins from structural templates: learning and benchmarks

scientific article published on September 2009

C-terminal arginine cluster is essential for receptor binding of norovirus capsid protein.

scientific article

Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms

scientific article

Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme

scientific article published on 30 March 2015

Combining prediction of secondary structure and solvent accessibility in proteins

scientific article (publication date: 15 May 2005)

Comprehensive analysis of sequences of a protein switch.

scientific article published on 12 June 2015

Computer simulations of carbon monoxide photodissociation in myoglobin: structural interpretation of the B states.

scientific article published on February 1998

Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution

scientific article

Cyclin D3 action in androgen receptor regulation and prostate cancer.

scientific article published on 17 December 2007

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

scientific article published on 13 November 2017

Deuterium Isotope Effects on Hydrophobic Interactions: The Importance of Dispersion Interactions in the Hydrophobic Phase ⬇️

scientific article published on November 12, 2003

Draft Assembly and Annotation of the Pneumocystis carinii Genome

scientific article published on 01 January 2006

Dual-channel single-molecule fluorescence resonance energy transfer to establish distance parameters for RNA nanoparticles

scientific article

Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study.

scientific article

Enhanced prediction of conformational flexibility and phosphorylation in proteins.

scientific article published in January 2010

Fast geometric consensus approach for protein model quality assessment

scientific article

Genetic and phenotypic characterization of GII-4 noroviruses that circulated during 1987 to 2008.

scientific article

Genetic risk signatures of opioid-induced respiratory depression following pediatric tonsillectomy

scientific article

Genomics Portals: integrative web-platform for mining genomics data.

scientific article

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH.

scientific article published on 31 August 2011

Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway

scientific article

Increased susceptibility of estrogen-induced bladder outlet obstruction in a novel mouse model.

scientific article published on 23 February 2015

Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections

scientific article (publication date: 2013)

Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak.

scientific article published on 15 October 2014

Linear programming optimization and a double statistical filter for protein threading protocols

scientific article published on 01 November 2001

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

scientific article

Maximum feasibility guideline in the design and analysis of protein folding potentials.

scientific article published in January 2002

Mutations within the P2 Domain of Norovirus Capsid Affect Binding to Human Histo-Blood Group Antigens: Evidence for a Binding Pocket ⬇️

scientific article published on December 1, 2003

Not all autophagy is equal

scientific article published on 31 May 2012

Novel associations between FAAH genetic variants and postoperative central opioid-related adverse effects.

scientific article published on 6 January 2015

Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics.

scientific article published on 14 October 2014

POLYVIEW-MM: web-based platform for animation and analysis of molecular simulations.

scientific article

Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin

scientific article

Prediction-based fingerprints of protein-protein interactions.

scientific article

Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

scientific article published on February 2012

Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.

scientific article

Rhesus rotavirus VP4 sequence-specific activation of mononuclear cells is associated with cholangiopathy in murine biliary atresia

scientific article

Rotavirus VP8*: phylogeny, host range, and interaction with histo-blood group antigens

scientific article

Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells.

scientific article

Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.

scientific article published on 25 April 2017

Solvent and lipid accessibility prediction as a basis for model quality assessment in soluble and membrane proteins.

scientific article

Substrate specificity of Tulane virus protease.

scientific article published on 8 November 2012

Survey of public domain software for docking simulations and virtual screening.

scientific article

TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.

scientific article published on 10 November 2014

Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance

scientific article

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

scientific article published on 24 November 2017

The SRL peptide of rhesus rotavirus VP4 protein governs cholangiocyte infection and the murine model of biliary atresia

scientific article

The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress

scientific article published on 19 February 2008

Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity

scientific article published on 16 July 2021

Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite

scientific article

Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression

scientific article published on 16 June 2016

UQlust: combining profile hashing with linear-time ranking for efficient clustering and analysis of big macromolecular data

scientific article

Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D

scientific article

iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells

scientific article

von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas

scientific article published on 26 October 2010

List of works by Jarek Meller

A Point Mutation in the Rhesus Rotavirus VP4 Protein Generated through a Rotavirus Reverse Genetics System Attenuates Biliary Atresia in the Murine Model

ABCC3 genetic variants are associated with postoperative morphine-induced respiratory depression and morphine pharmacokinetics in children

Accurate prediction of solvent accessibility using neural networks-based regression.

Analysis of current antifungal agents and their targets within the Pneumocystis carinii genome.

Building and assessing atomic models of proteins from structural templates: learning and benchmarks

C-terminal arginine cluster is essential for receptor binding of norovirus capsid protein.

Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms

Combined rational design and a high throughput screening platform for identifying chemical inhibitors of a Ras-activating enzyme

Combining prediction of secondary structure and solvent accessibility in proteins

Comprehensive analysis of sequences of a protein switch.

Computer simulations of carbon monoxide photodissociation in myoglobin: structural interpretation of the B states.

Conservation of carbohydrate binding interfaces: evidence of human HBGA selection in norovirus evolution

Cyclin D3 action in androgen receptor regulation and prostate cancer.

Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data

Deuterium Isotope Effects on Hydrophobic Interactions: The Importance of Dispersion Interactions in the Hydrophobic Phase ⬇️

Draft Assembly and Annotation of the Pneumocystis carinii Genome

Dual-channel single-molecule fluorescence resonance energy transfer to establish distance parameters for RNA nanoparticles

Elucidation of strain-specific interaction of a GII-4 norovirus with HBGA receptors by site-directed mutagenesis study.

Enhanced prediction of conformational flexibility and phosphorylation in proteins.

Fast geometric consensus approach for protein model quality assessment

Genetic and phenotypic characterization of GII-4 noroviruses that circulated during 1987 to 2008.

Genetic risk signatures of opioid-induced respiratory depression following pediatric tonsillectomy

Genomics Portals: integrative web-platform for mining genomics data.

Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH.

Identification of a conserved anti-apoptotic protein that modulates the mitochondrial apoptosis pathway

Increased susceptibility of estrogen-induced bladder outlet obstruction in a novel mouse model.

Inhibition of histo-blood group antigen binding as a novel strategy to block norovirus infections

Interaction between Na-K-ATPase and Bcl-2 proteins BclXL and Bak.

Linear programming optimization and a double statistical filter for protein threading protocols

Localization of Rac2 via the C terminus and aspartic acid 150 specifies superoxide generation, actin polarity and chemotaxis in neutrophils.

Maximum feasibility guideline in the design and analysis of protein folding potentials.

Mutations within the P2 Domain of Norovirus Capsid Affect Binding to Human Histo-Blood Group Antigens: Evidence for a Binding Pocket ⬇️

Not all autophagy is equal

Novel associations between FAAH genetic variants and postoperative central opioid-related adverse effects.

Opioid-induced respiratory depression: ABCB1 transporter pharmacogenetics.

POLYVIEW-MM: web-based platform for animation and analysis of molecular simulations.

Phosphorylation-dependent conformational transition of the cardiac specific N-extension of troponin I in cardiac troponin

Prediction-based fingerprints of protein-protein interactions.

Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation.

Rational design of small molecule inhibitors targeting the Ras GEF, SOS1.

Rhesus rotavirus VP4 sequence-specific activation of mononuclear cells is associated with cholangiopathy in murine biliary atresia

Rotavirus VP8*: phylogeny, host range, and interaction with histo-blood group antigens

Secretory phospholipase A2-IIa upregulates HER/HER2-elicited signaling in lung cancer cells.

Significant variation between SNP-based HLA imputations in diverse populations: the last mile is the hardest.

Solvent and lipid accessibility prediction as a basis for model quality assessment in soluble and membrane proteins.

Substrate specificity of Tulane virus protease.

Survey of public domain software for docking simulations and virtual screening.

TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.

Targeting substrate-site in Jak2 kinase prevents emergence of genetic resistance

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations

The SRL peptide of rhesus rotavirus VP4 protein governs cholangiocyte infection and the murine model of biliary atresia

The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress

Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity

Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite

Traumatic Brain Injury Induces Alterations in Cortical Glutamate Uptake without a Reduction in Glutamate Transporter-1 Protein Expression

UQlust: combining profile hashing with linear-time ranking for efficient clustering and analysis of big macromolecular data

Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D

iTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells

von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomas