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List of works by M. Leonor Cancela

1 alpha,25(OH)2 vitamin D3: a steroid hormone capable of producing pleiotropic receptor-mediated biological responses by both genomic and nongenomic mechanisms

scientific article published on January 1988

A Microarray Study of Carpet-Shell Clam (Ruditapes decussatus) Shows Common and Organ-Specific Growth-Related Gene Expression Differences in Gills and Digestive Gland

scientific article published on 28 November 2017

A revision of the status of Lepadogaster lepadogaster (Teleostei: Gobiesocidae): sympatric subspecies or a long misunderstood blend of species?

An oxygen molecular sensor, the HIF prolyl 4-hydroxylase, in the marine protist Perkinsus olseni.

scientific article published on 9 June 2008

Cardiomyocyte H9c2 cells present a valuable alternative to fish lethal testing for azoxystrobin.

scientific article published on 25 August 2015

Central role of betaine-homocysteine S-methyltransferase 3 in chondral ossification and evidence for sub-functionalization in neoteleost fish.

scientific article published on 29 March 2016

Changes in bioturbation of iron biogeochemistry and in molecular response of the clam Ruditapes decussates upon Perkinsus olseni infection.

scientific article published on 16 March 2010

Characterization of Sparus aurata osteonectin cDNA and in silico analysis of protein conserved features: evidence for more than one osteonectin in Salmonidae.

scientific article

Cholecalciferol sulfate identification in human milk by HPLC

scientific article published on 01 April 1982

Cloning and characterization of the cDNA and gene encoding Xenopus laevis osteocalcin.

scientific article

Cloning of matrix Gla protein in a marine cartilaginous fish, Prionace glauca: preferential protein accumulation in skeletal and vascular systems

scientific article published on 13 January 2006

Cloning of the bone Gla protein gene from the teleost fish Sparus aurata. Evidence for overall conservation in gene organization and bone-specific expression from fish to man.

scientific article published in May 2001

Comparative analysis of zebrafish bone morphogenetic proteins 2, 4 and 16: molecular and evolutionary perspectives.

scientific article

Correction: Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum

scientific article published in PLoS ONE

Development and characterization of Xl1, a Xenopus laevis chondrocyte-like cell culture.

scientific article

Development of a PCR-ELISA assay for diagnosis of Perkinsus marinus and Perkinsus atlanticus infections in bivalve molluscs.

scientific article published in April 2004

Development of two bone-derived cell lines from the marine teleost Sparus aurata; evidence for extracellular matrix mineralization and cell-type-specific expression of matrix Gla protein and osteocalcin.

scientific article

Dietary supplementation with vitamin k affects transcriptome and proteome of Senegalese sole, improving larval performance and quality

scientific article published on 03 May 2014

Distinct patterns of notochord mineralization in zebrafish coincide with the localization of Osteocalcin isoform 1 during early vertebral centra formation

scientific article

Dual transcriptional regulation by runx2 of matrix Gla protein in Xenopus laevis.

scientific article

Effect of desferrioxamine and 2,2'-bipyridyl on the proliferation of Perkinsus atlanticus

scientific article published in July 2003

Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone.

scientific article

Enhanced DNA transfer into fish bone cells using polyethylenimine.

scientific article published on September 2006

Evidence for the conservation of miR-223 in zebrafish (Danio rerio): Implications for function.

scientific article

Evidences for a New Role of miR-214 in Chondrogenesis.

scientific article published on 27 February 2018

Evolutionary conservation of TFIIH subunits: implications for the use of zebrafish as a model to study TFIIH function and regulation

scientific article published on 13 April 2014

Expression pattern of cdkl5 during zebrafish early development: implications for use as model for atypical Rett syndrome

article

Expression pattern ofPerkinsus olsenigenes in response to bivalves with different susceptibility to perkinsosis

scientific article published on 01 July 2009

Four-and-a-half LIM domains protein 2 (FHL2) is associated with the development of craniofacial musculature in the teleost fish Sparus aurata

scientific article published on 08 July 2011

Gla-rich protein is a novel vitamin K-dependent protein present in serum that accumulates at sites of pathological calcifications.

scientific article

Gla-rich protein, a new player in tissue calcification?

scientific article (publication date: March 2012)

Global analysis of gene expression in mineralizing fish vertebra-derived cell lines: new insights into anti-mineralogenic effect of vanadate

scientific article

Identification of a fish short-chain dehydrogenase/reductase associated with bone metabolism.

scientific article published on 14 December 2017

Identification of a new pebp2alphaA2 isoform from zebrafish runx2 capable of inducing osteocalcin gene expression in vitro.

scientific article

Identification of a novel negative retinoic acid responsive element in the promoter of the human matrix Gla protein gene

scientific article

Identification of a promoter element within the zebrafish colXalpha1 gene responsive to runx2 isoforms Osf2/Cbfa1 and til-1 but not to pebp2alphaA2.

scientific article published on 10 October 2006

Identification of an osteocalcin isoform in fish with a large acidic prodomain.

scientific article published on 24 March 2006

Identification of an osteopontin-like protein in fish associated with mineral formation.

scientific article

Impairment of mineralization by metavanadate and decavanadate solutions in a fish bone-derived cell line.

scientific article

Improved regeneration and de novo bone formation in a diabetic zebrafish model treated with paricalcitol and cinacalcet.

scientific article published on 5 April 2017

Iron overload in a murine model of hereditary hemochromatosis is associated with accelerated progression of osteoarthritis under mechanical stress

scientific article published on 25 September 2015

Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis

scientific article published in PLoS ONE

Isolation and characterization of polymorphic microsatellite markers in Abudefduf luridus (Pisces: Pomacentridae)

scientific article published on 01 July 2000

MEF2C orthologues from zebrafish: Evolution, expression and promoter regulation

scientific article published on 16 December 2015

Matrix Gla Protein expression pattern in the early avian embryo

scientific article

Matrix Gla protein and osteocalcin: from gene duplication to neofunctionalization.

scientific article

Matrix Gla protein gene expression and protein accumulation colocalize with cartilage distribution during development of the teleost fish Sparus aurata

scientific article (publication date: March 2003)

Matrix Gla protein in turbot (Scophthalmus maximus): Gene expression analysis and identification of sites of protein accumulation

article

Matrix Gla protein repression by miR-155 promotes oncogenic signals in breast cancer MCF-7 cells.

scientific article published on 24 March 2016

MiR-29a is an enhancer of mineral deposition in bone-derived systems.

scientific article published on 18 September 2014

Micro-anatomical characterization of vertebral curvatures in Senegalese sole Solea senegalensis.

scientific article published on 5 May 2015

Mir-20a regulates in vitro mineralization and BMP signaling pathway by targeting BMP-2 transcript in fish

scientific article published on 21 December 2013

Molecular characterization of cbfβ gene and identification of new transcription variants: implications for function.

scientific article published on 6 January 2015

Molecular cloning of the Matrix Gla Protein gene from Xenopus laevis. Functional analysis of the promoter identifies a calcium sensitive region required for basal activity

article

Molecular effect of an OPTN common variant associated to Paget's disease of bone.

scientific article

Molecular insights into the taxonomic status of Coris atlantica (Pisces: Labridae)

scholarly article in Journal of the Marine Biological Association of the United Kingdom, vol. 80 no. 5, October 2000

Multiple paternity in Norway lobster (Nephrops norvegicus L.) assessed with microsatellite markers.

scientific article published on 20 October 2003

Nutrient limitation is the main regulatory factor for carotenoid accumulation and for Psy and Pds steady state transcript levels in Dunaliella salina (Chlorophyta) exposed to high light and salt stress.

scientific article published in May 2008

Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L.): cloning, tissue expression and comparative aspects.

scientific article published on November 2007

Osteocalcin and matrix GLA protein in developing teleost teeth: identification of sites of mRNA and protein accumulation at single cell resolution

scientific article published on 01 August 2005

Osteocalcin and matrix Gla protein in zebrafish (Danio rerio) and Senegal sole (Solea senegalensis): comparative gene and protein expression during larval development through adulthood.

scientific article published on 2 February 2006

Osteological development and abnormalities of the vertebral column and caudal skeleton in larval and juvenile stages of hatchery-reared Senegal sole (Solea senegalensis)

scientific article

Osteotoxicity of 3-methylcholanthrene in fish

scientific article published on 22 June 2018

Overexpression of four and a half LIM domains protein 2 promotes epithelial-mesenchymal transition-like phenotype in fish pre-osteoblasts.

scientific article published on 20 January 2012

Purification of matrix Gla protein from a marine teleost fish, Argyrosomus regius: calcified cartilage and not bone as the primary site of MGP accumulation in fish.

scientific article

Quantitative assessment of the regenerative and mineralogenic performances of the zebrafish caudal fin

scientific article published on 19 December 2016

Rapid identification of differentially expressed genes by in situ screening of bacteria.

scientific article

Red algal extracts from Plocamium lyngbyanum and Ceramium secundatum stimulate osteogenic activities in vitro and bone growth in zebrafish larvae.

scientific article

Regulation of 24-hydroxylase activity in mouse skin fibroblast by cholecalciferol derivatives, triamcinolone acetonide and a calcium modulating agent, nicardipine

scientific article published on 01 November 1987

Revisiting in vivo staining with alizarin red S--a valuable approach to analyse zebrafish skeletal mineralization during development and regeneration

scientific article published on 19 January 2016

Screening for osteogenic activity in extracts from Irish marine organisms: The potential of Ceramium pallidum

scientific article published in PLoS ONE

Structural Evidence of a Fourth Gla Residue in Fish Osteocalcin: Biological Implications†,‡

scientific article published on 01 February 2005

Sturgeon osteocalcin shares structural features with matrix Gla protein: evolutionary relationship and functional implications.

scientific article published on 24 July 2013

Suppression subtractive hybridization for studying gene expression during aerial exposure and desiccation in fucoid algae

article

The antifreeze protein type I (AFP I) increases seabream (Sparus aurata) embryos tolerance to low temperatures.

scientific article published on 07 June 2007

The role of calcium concentration in the invasive capacity of Corbicula fluminea in crystalline basins

scientific article

The xenobiotic sensor PXR in a marine flatfish species (Solea senegalensis): Gene expression patterns and its regulation under different physiological conditions.

scientific article published on 23 July 2017

The zebrafish operculum: A powerful system to assess osteogenic bioactivities of molecules with pharmacological and toxicological relevance.

scientific article published on 27 April 2017

Time course studies on phosphate transfer in frog urinary bladder.

scientific article

Transcription factors from Sox family regulate expression of zebrafish Gla-rich protein 2 gene.

scientific article

Transcriptional regulation of gilthead seabream bone morphogenetic protein (BMP) 2 gene by bone- and cartilage-related transcription factors.

scientific article

Transcriptome sequencing and microarray development for the Manila clam, Ruditapes philippinarum: genomic tools for environmental monitoring

scientific article

Vestiges, rudiments and fusion events: the zebrafish caudal fin endoskeleton in an evo-devo perspective.

scientific article published in January 2012

Warfarin, a potential pollutant in aquatic environment acting through Pxr signaling pathway and γ-glutamyl carboxylation of vitamin K-dependent proteins.

scientific article published on 4 August 2014

ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor.

scientific article published on February 2016

Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure.

scientific article published on 20 March 2015

mRNA-Seq and microarray development for the Grooved Carpet shell clam, Ruditapes decussatus: a functional approach to unravel host-parasite interaction. ⬇️

scientific article

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