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List of works by Owen Rackham

A Bayesian Approach for Analysis of Whole-Genome Bisulfite Sequencing Data Identifies Disease-Associated Changes in DNA Methylation

scientific article

A Ca-Based Computational Model for NMDA Receptor-Dependent Synaptic Plasticity at Individual Post-Synaptic Spines in the Hippocampus

scientific article published on 21 July 2010

A Proteome Quality Index

scientific article published on 22 October 2014

A daily-updated tree of (sequenced) life as a reference for genome research.

scientific article

A predictive computational framework for direct reprogramming between human cell types

scientific article

A promoter-level mammalian expression atlas

scientific article

A single-cell atlas of entorhinal cortex from individuals with Alzheimer's disease reveals cell-type-specific gene expression regulation

scientific article published on 01 December 2019

An atlas of active enhancers across human cell types and tissues

scientific article

An atlas of human long non-coding RNAs with accurate 5' ends.

scientific article

Cell Type of Origin Dictates the Route to Pluripotency.

scientific article published in December 2017

Characterising the loss-of-function impact of 5' untranslated region variants in 15,708 individuals

scientific article published on 27 May 2020

Characterising the loss-of-function impact of 5' untranslated region variants in whole genome sequence data from 15,708 individuals

Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

scientific article published on 09 April 2021

Computational Stem Cell Biology: Open Questions and Guiding Principles

scientific article published on 01 January 2021

Computational methods for direct cell conversion

scientific article

EvoTol: a protein-sequence based evolutionary intolerance framework for disease-gene prioritization

scientific article published on 29 December 2014

Exploring uncertainties in the relationship between temperature, ice volume, and sea level over the past 50 million years

article by Edward Gasson et al published 19 January 2012 in Reviews of Geophysics

Function-selective domain architecture plasticity potentials in eukaryotic genome evolution

scientific article published on 15 May 2015

Functional annotation of human long noncoding RNAs via molecular phenotyping

scientific article published on 27 July 2020

Genome3D: a UK collaborative project to annotate genomic sequences with predicted 3D structures based on SCOP and CATH domains

scientific article

Genome3D: exploiting structure to help users understand their sequences

scientific article

IL-11 is a crucial determinant of cardiovascular fibrosis.

scientific article

Integrated systems-genetic analyses reveal a network target for delaying glioma progression

scientific article published on 17 August 2019

Let it RE:IN: integrating experimental observations to predict pluripotency network behaviour

scientific article published on 13 December 2018

Molecular Interaction Networks to Select Factors for Cell Conversion

scientific article published on 01 January 2019

Potassium channel dysfunction in human neuronal models of Angelman syndrome

scientific article published on 01 December 2019

RNA polymerase II primes Polycomb-repressed developmental genes throughout terminal neuronal differentiation.

scientific article published on 16 October 2017

SUPERFAMILY 1.75 including a domain-centric gene ontology method

scientific article

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

scientific article published on 21 December 2015

The SUPERFAMILY 1.75 database in 2014: a doubling of data

scientific article

The evolution and structure prediction of coiled coils across all genomes

scientific article published on 9 September 2010

The evolution of human cells in terms of protein innovation

scientific article

Titin-truncating variants affect heart function in disease cohorts and the general population.

scientific article

Transcriptional signature in microglia associated with Aβ plaque phagocytosis

scientific article published on 21 May 2021

Update of the FANTOM web resource: high resolution transcriptome of diverse cell types in mammals

scientific article published on 27 October 2016

WGBSSuite: simulating whole-genome bisulphite sequencing data and benchmarking differential DNA methylation analysis tools

scientific article

WWP2 regulates pathological cardiac fibrosis by modulating SMAD2 signaling

scientific article published on 09 August 2019

Web-based Gene Pathogenicity Analysis (WGPA): a web platform to interpret gene pathogenicity from personal genome data

scientific article

Whole-Genome Sequencing of Finnish Type 1 Diabetic Siblings Discordant for Kidney Disease Reveals DNA Variants associated with Diabetic Nephropathy

scientific article published on 09 January 2020

Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins

scientific article published on 09 July 2019