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List of works by Elizabeth Brunk

A Multi-scale Computational Platform to Mechanistically Assess the Effect of Genetic Variation on Drug Responses in Human Erythrocyte Metabolism

scientific article

A streamlined ribosome profiling protocol for the characterization of microorganisms

scientific article published on January 2014

Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes

scientific article published on 26 May 2018

Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System

scientific article published on 15 June 2018

Characterizing Strain Variation in Engineered E. coli Using a Multi-Omics-Based Workflow.

scientific article published on 19 May 2016

Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow

article published in the Proceedings of the National Academy of Sciences of the United States of America

Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism

scientific article published in Nature Communications

Growth Adaptation of and Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

article published in 2018

Machine learning in computational biology to accelerate high-throughput protein expression.

scientific article published on 07 April 2017

Model-driven discovery of synergistic inhibitors against E. coli and S. enterica serovar Typhimurium targeting a novel synthetic lethal pair, aldA and prpC

scientific article published on 23 September 2015

Model-driven discovery of underground metabolic functions in Escherichia coli

scientific article

Multi-omic data integration enables discovery of hidden biological regularities

scientific article

Multiple Optimal Phenotypes Overcome Redox and Glycolytic Intermediate Metabolite Imbalances in Escherichia coli pgi Knockout Evolutions

scientific article published on 17 September 2018

Recon3D enables a three-dimensional view of gene variation in human metabolism.

scientific article published on 19 February 2018

Systems biology of the structural proteome

scientific article

The Need for Integrated Approaches in Metabolic Engineering.

scientific article published on 15 August 2016

iML1515, a knowledgebase that computes Escherichia coli traits.

scientific article published in October 2017

ssbio: A Python Framework for Structural Systems Biology

scientific article published on 12 February 2018