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List of works by Angeleen Fleming

A central role for the notochord in vertebral patterning

scientific article published on 21 January 2004

A rapid, high content, in vivo model of glucocorticoid-induced osteoporosis.

scientific article published in June 2006

Accumulation and metabolism of drugs and CYP probe substrates in zebrafish larvae.

scientific article published in August 2010

Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.

scientific article published on 21 June 2010

Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities

scientific article published on March 2017

Autophagy regulates Notch degradation and modulates stem cell development and neurogenesis.

scientific article

Building the backbone: the development and evolution of vertebral patterning

scientific article

Chemical modulators of autophagy as biological probes and potential therapeutics

scientific article published on January 2011

Complex inhibitory effects of nitric oxide on autophagy

scientific article

Compromised autophagy and neurodegenerative diseases

scientific article published on June 2015

Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish.

scientific article published in February 2009

Drug reprofiling using zebrafish identifies novel compounds with potential pro-myelination effects

scientific article

Embryonic folate metabolism and mouse neural tube defects

scientific article published in June 1998

Expression and regulation of drug transporters in vertebrate neutrophils

scientific article

Functional characterisation of the maturation of the blood-brain barrier in larval zebrafish

scientific article (publication date: 2013)

Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion.

scientific article

Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death

scientific article

High-throughput in vivo screening for bone anabolic compounds with zebrafish.

scientific article published on 18 October 2005

IGF-1 receptor antagonism inhibits autophagy

scientific article published on 25 June 2013

Loss of PINK1 function affects development and results in neurodegeneration in zebrafish

scientific article published in August 2008

Molecular analysis of axon repulsion by the notochord

scientific article

Non-associative learning in larval zebrafish.

scientific article published on 20 June 2007

PICALM modulates autophagy activity and tau accumulation

scientific article

Seeing is believing: methods to monitor vertebrate autophagy

article

Zebrafish based assays for the assessment of cardiac, visual and gut function--potential safety screens for early drug discovery

scientific article published on 08 June 2008

cGMP via PKG activates 26S proteasomes and enhances degradation of proteins, including ones that cause neurodegenerative diseases

scientific article published on 08 June 2020

siRNA screen identifies QPCT as a druggable target for Huntington's disease

scientific article

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