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List of works by Katrin Ottersbach

2005 - GATA3 PROMOTES THE ENDOTHELIAL-TO-HEMATOPOIETIC TRANSITION VIA REGULATION OF THE CELL CYCLE

scholarly article

A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis

scientific article

A310 helical turn is essential for the proliferation-inhibiting properties of macrophage inflammatory protein-1 alpha (CCL3)

scientific article published on 18 October 2005

Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia

scientific article published on 17 January 2013

An Unexpected Role for IL-3 in the Embryonic Development of Hematopoietic Stem Cells

scientific article published on 01 August 2006

Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation.

scientific article published on 10 February 2016

Analysis of the mouse placenta as a hematopoietic stem cell niche.

scientific article published in January 2009

CD41 is developmentally regulated and differentially expressed on mouse hematopoietic stem cells ⬇️

scientific article published on March 17, 2011

Concise review: From greenhouse to garden: the changing soil of the hematopoietic stem cell microenvironment during development

scientific article published on July 2014

DNA damage signalling from the placenta to foetal blood as a potential mechanism for childhood leukaemia initiation

scientific article published on 13 March 2019

Defining the Developmental Origin of MLL-AF4-Driven Infant Leukaemia

scholarly article

Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages

scientific article

Developmental origins of hematopoietic stem cells.

scientific article

Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.

scientific article published on 16 July 2012

ESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoforms

scientific journal article

Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.

scientific article

Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells

scholarly article

Endoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast code

scientific article published on 19 September 2008

Endothelial-to-haematopoietic transition: an update on the process of making blood

scientific article published on 22 March 2019

Fetal liver Mll-AF4+ hematopoietic stem and progenitor cells respond directly to poly(I:C), but not to a single maternal immune activation

scientific article published on 02 August 2019

GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells

scientific article

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

scientific journal article

Gata3 targets Runx1 in the embryonic haematopoietic stem cell niche

scientific article published on 21 October 2019

Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.

scientific article

Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.

scientific article

Hematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient mice

Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.

scientific article

High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice

scientific article published on 18 February 2015

Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.

scientific article

Infant leukaemia – faithful models, cell of origin and the niche

scientific article published on 29 October 2021

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia

scientific article

MIR-128A AND MIR-130B DETERMINE LINEAGE CHOICE AND LEUKEMIA-PROPAGATING CELL IDENTITY IN MLL-AF4+ ACUTE LEUKEMIA

scholarly article

Macrophage inflammatory protein-1alpha uses a novel receptor for primitive hemopoietic cell inhibition

scientific article published on 01 December 2001

Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development

scientific article published on 6 July 2016

Molecular processes involved in B cell acute lymphoblastic leukaemia.

scientific article published on 17 August 2017

Ontogeny of haematopoiesis: recent advances and open questions

scientific article published on 22 October 2009

Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver

scientific journal article

SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development

scientific article published on 13 April 2015

Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis

scientific article

Single cell analyses and machine learning define hematopoietic progenitor and HSC-like cells derived from human PSCs

scientific article published on 02 July 2020

Single cell transcriptome analysis reveals markers of naïve and lineage-primed hematopoietic progenitors derived from human pluripotent stem cells

The "Never-Ending" Mouse Models for MLL-Rearranged Acute Leukemia Are Still Teaching Us

scientific article published on 19 June 2018

The Ly‐6A (Sca‐1) GFP Transgene is Expressed in all Adult Mouse Hematopoietic Stem Cells

scientific article published on 01 January 2002

The MLL/SET family and haematopoiesis

scientific article published on 07 May 2020

The fetal liver lymphoid-primed multipotent progenitor provides the prerequisites for the initiation of t(4;11) MLL-AF4 infant leukemia

scientific article published on 14 June 2018

The multi-faceted role of Gata3 in developmental haematopoiesis

The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.

scientific article published in March 2005

The placenta as a haematopoietic organ.

scientific article published on January 2010

The unconventional embryo: immune-restricted potential precedes multipotentiality.

scientific article published in November 2013

Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development

scientific article

cis-Regulatory remodeling of the SCL locus during vertebrate evolution.

scientific article published on 18 October 2010

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion

scientific article published on 2 June 2022

p57Kip2 regulates embryonic haematopoietic stem cell numbers by controlling the size of the sympathoadrenal progenitor pool

Scientific preprint posted 13 September 2021

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