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List of works by Diego Fornasari

A "novel" association to treat pain: tramadol/dexketoprofen. The first drug of a "new pharmacological class"

scientific article published on 28 April 2017

Acetylcholinesterase inhibitors targeting the cholinergic anti-inflammatory pathway: a new therapeutic perspective in aging-related disorders

scientific article published on 03 October 2019

Adverse Effects Associated with Non-opioid and Opioid Treatment in Patients with Chronic Pain

scientific article published on February 1, 2012

Alanine Expansions Associated with Congenital Central Hypoventilation Syndrome Impair PHOX2B Homeodomain-mediated Dimerization and Nuclear Import

scientific article published on 27 April 2016

Anti-neuronal nicotinic receptor antibodies in MG patients with thymoma.

scientific article

Association between SNAP-25 gene polymorphisms and cognition in autism: functional consequences and potential therapeutic strategies

scientific article

Barriers to pain management: focus on opioid therapy

scientific article published on February 2012

Breakthrough cancer pain (BTcP): a synthesis of taxonomy, pathogenesis, therapy, and good clinical practice in adult patients in Italy.

scientific article

Chromosomal localization and physical linkage of the genes encoding the human alpha 3, alpha 5, and beta 4 neuronal nicotinic receptor subunits

scientific article (publication date: April 1992)

Distribution of nicotinic receptors in cynomolgus monkey brain and ganglia: localization of alpha 3 subunit mRNA, alpha-bungarotoxin and nicotine binding sites

scientific article published on November 1, 1992

Expression of neuronal acetylcholine nicotinic receptor alpha 4 and beta 2 subunits during postnatal development of the rat brain

scientific article published on 01 January 1995

Expression of the alpha3 nicotinic receptor subunit mRNA in aging and Alzheimer's disease.

scientific article published in December 1998

Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.

scientific article published on January 2011

Extremely low-frequency electromagnetic field (ELF-EMF) does not affect the expression of alpha3, alpha5 and alpha7 nicotinic receptor subunit genes in SH-SY5Y neuroblastoma cell line

scientific article published on 2 March 2006

Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis

scientific article

Genomic organization and transcription of the human retinol dehydrogenase 10 (RDH10) gene

scientific journal article

Human neuronal nicotinic receptors ⬇️

scientific article published on October 1, 1997

Identification and characterization of regulatory elements in the promoter of ACVR1, the gene mutated in Fibrodysplasia Ossificans Progressiva.

scientific article

Identification of novel pathways and molecules able to down-regulate PHOX2B gene expression by in vitro drug screening approaches in neuroblastoma cells

scientific article published on 13 April 2015

In vitro drug treatments reduce the deleterious effects of aggregates containing polyAla expanded PHOX2B proteins

scientific article published on 21 September 2011

In vivo RNA-RNA duplexes from human alpha3 and alpha5 nicotinic receptor subunit mRNAs

scientific article

LIN7 regulates the filopodium- and neurite-promoting activity of IRSp53.

scientific article

Molecular cloning of human neuronal nicotinic receptor alpha 3-subunit

scientific article (publication date: 6 April 1990)

Molecular insights into the role of the polyalanine region in mediating PHOX2B aggregation

scientific article published on 16 April 2019

Molecular mechanism of the aryl hydrocarbon receptor activation by the fungicide iprodione in rainbow trout (Oncorhynchus mykiss) hepatocytes.

scientific article published on 26 January 2005

Neuronal and extraneuronal expression and regulation of the human alpha5 nicotinic receptor subunit gene.

scientific article

Neuronal nicotinic acetylcholine receptors: from structure to therapeutics

scientific article published on 01 February 2000

Novel localisation and possible function of LIN7 and IRSp53 in mitochondria of HeLa cells.

scientific article published on 24 May 2016

PHOX2A and PHOX2B are differentially regulated during retinoic acid-driven differentiation of SK-N-BE(2)C neuroblastoma cell line

scientific article published on 18 February 2016

PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma

scientific article

Pain mechanisms in patients with chronic pain

scientific article published on February 2012

Pain mechanisms in patients with chronic pain

scientific article published in February 2012

Paracetamol: a probably still safe drug.

scientific article published on 10 May 2016

Pharmacology of pain.

scientific article

Regular use of acetaminophen or acetaminophen–codeine combinations and prescription of rescue therapy with non-steroidal anti-inflammatory drugs: a population-based study in primary care

Response of rainbow trout (Oncorhynchus mykiss) D-11 cell line to 3-methylcholanthrene (3MC) exposure.

scientific article published on August 2002

SOD1 stimulates lamellipodial protrusions in Neuro 2A cell lines

scientific article published on 09 August 2018

Structural and functional differences in PHOX2B frameshift mutations underlie isolated or syndromic congenital central hypoventilation syndrome.

scientific article

The Appropriate Treatment of Chronic Pain

scientific article published on February 1, 2012

The E3 ubiquitin ligase TRIM11 mediates the degradation of congenital central hypoventilation syndrome-associated polyalanine-expanded PHOX2B.

scientific article published on 4 February 2012

The TLX2 homeobox gene is a transcriptional target of PHOX2B in neural-crest-derived cells

scientific article

The binding site for alpha-bungarotoxin resides in the sequence 188-201 of the alpha-subunit of acetylcholine receptor: structure, conformation and binding characteristics of peptide [Lys] 188-201

scientific article published on 01 November 1987

The expression of GHS-R in primary neurons is dependent upon maturation stage and regional localization

scientific article

The expression of PHOX2A, PHOX2B and of their target gene dopamine-beta-hydroxylase (DbetaH) is not modified by exposure to extremely-low-frequency electromagnetic field (ELF-EMF) in a human neuronal model

scientific article

The expression of the human neuronal alpha3 Na+,K+-ATPase subunit gene is regulated by the activity of the Sp1 and NF-Y transcription factors

scientific article

The minimal promoter of the human alpha 3 nicotinic receptor subunit gene. Molecular and functional characterization.

scientific article published on December 2000

Transcription factor PHOX2A regulates the human alpha3 nicotinic receptor subunit gene promoter

scientific article

Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism induced by polyalanine expansion mutations associated with congenital central hypoventilation syndrome

scientific article

Transcriptional regulation of TLX2 and impaired intestinal innervation: possible role of the PHOX2A and PHOX2B genes

scientific article published on 16 May 2007

Transcriptional regulation of the human alpha5 nicotinic receptor subunit gene in neuronal and non-neuronal tissues

scientific article (publication date: 30 March 2000)

Transgenic mice expressing human alpha 3 Na,K-ATPase isoform in heart

scientific article published on 01 November 1997

Tryptophan hydroxylase type 2 variants modulate severity and outcome of addictive behaviors in Parkinson's disease

scientific article published on 17 May 2016

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