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List of works by Zheng Ruan

Altered conformational landscape and dimerization dependency underpins the activation of EGFR by αC-β4 loop insertion mutations.

scientific article published on 13 August 2018

Computational and Experimental Characterization of Patient Derived Mutations Reveal an Unusual Mode of Regulatory Spine Assembly and Drug Sensitivity in EGFR Kinase.

scientific article

Integrative annotation and knowledge discovery of kinase post-translational modifications and cancer-associated mutations through federated protein ontologies and resources.

scientific article

LF4/MOK and a CDK-related kinase regulate the number and length of cilia in Tetrahymena

scientific article published on 24 July 2019

Structures and pH-sensing mechanism of the proton-activated chloride channel

scientific article published on 04 November 2020

Structures of human pannexin 1 reveal ion pathways and mechanism of gating

scientific article published on 03 June 2020

Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1

scientific article published on 25 September 2018

Two Antagonistic Hippo Signaling Circuits Set the Division Plane at the Medial Position in the Ciliate Tetrahymena

scientific article published on 28 December 2018

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