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List of works by Louise Fairall

A Pharmacogenetic Approach to the Treatment of Patients with PPARG Mutations.

scientific article published on 5 April 2018

A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death

scientific article

A new approach to the analysis of DNase I footprinting data and its application to the TFIIIA/5S DNA complex.

scientific article

An evolving understanding of nuclear receptor coregulator proteins.

scientific article

Aster Proteins Facilitate Nonvesicular Plasma Membrane to ER Cholesterol Transport in Mammalian Cells

scientific article published on 13 September 2018

Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake

scientific article published on 09 November 2023

Backbone resonance assignment of the BCL6-BTB/POZ domain

scientific article published on 19 September 2017

Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

scientific article

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

scientific article

Contrasting Phenotypes in Resistance to Thyroid Hormone Alpha Correlate with Divergent Properties of Thyroid Hormone Receptor α1 Mutant Proteins

scientific article published on 4 May 2017

EM measurements define the dimensions of the "30-nm" chromatin fiber: evidence for a compact, interdigitated structure

scientific article

EXAFS study of the zinc-binding sites in the protein transcription factor IIIA

scientific article published in Nature

Expression and Purification of Protein Complexes Suitable for Structural Studies Using Mammalian HEK 293F Cells.

scientific article published in November 2017

FERM-dependent E3 ligase recognition is a conserved mechanism for targeted degradation of lipoprotein receptors

scientific article published on 22 November 2011

Genetic disorders of nuclear receptors

scientific article

How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures

scientific article

Insights into the Recruitment of Class IIa Histone Deacetylases (HDACs) to the SMRT/NCoR Transcriptional Repression Complex

scientific article published on 8 June 2015

Mapping of the sites of protection on a 5 S RNA gene by the Xenopus transcription factor IIIA. A model for the interaction

scientific article published on 01 December 1986

Mutations in TBL1X Are Associated With Central Hypothyroidism.

scientific article published on 07 September 2016

NOXA, a sensor of proteasome integrity, is degraded by 26S proteasomes by an ubiquitin-independent pathway that is blocked by MCL-1

scientific article published on 24 February 2012

Negative regulation by nuclear receptors: a plethora of mechanisms

scientific article published on 31 December 2010

Nuclear hormone receptor co-repressors: structure and function.

scientific article published on 08 September 2011

Oligonucleotide binding to the coat protein disk of tobacco mosaic virus. Possible steps in the mechanism of assembly

scientific article

Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach.

scientific article published on 16 October 2014

Sequence-specific DNA recognition by the Myb-like domain of the human telomere binding protein TRF1: A model for the protein-DNA complex ⬇️

scientific article published on April 1, 1998

Single crystals of long DNA molecules

scientific article published on 01 February 1992

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting

scientific article

Structural basis for the activation of PPARgamma by oxidized fatty acids

scientific article

Structural basis for the assembly of the SMRT/NCoR core transcriptional repression machinery

scientific article

Structure of HDAC3 bound to co-repressor and inositol tetraphosphate

scientific article

Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2

scientific article

Studies of tobacco mosaic virus reassembly with an RNA tail blocked by a hybridised and cross-linked probe

scientific article

TRF1 binds a bipartite telomeric site with extreme spatial flexibility

scientific article

Targeting Class I Histone Deacetylases in a "Complex" Environment

scientific article published on 27 January 2017

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors

scientific article published on 4 January 2018

Telomere architecture

scientific article

The DNA binding site of the Xenopus transcription factor IIIA has a non-B-form structure

scientific article

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

scientific article

The ansamycin antibiotic, rifamycin SV, inhibits BCL6 transcriptional repression and forms a complex with the BCL6-BTB/POZ domain

scientific article

The cocrystal structures of two zinc-stabilized DNA-binding domains illustrate different ways of achieving sequence-specific DNA recognition.

scientific article published in January 1993

The crystal structure of a two zinc-finger peptide reveals an extension to the rules for zinc-finger/DNA recognition

scientific article

Towards an understanding of the structure and function of MTA1

scientific article

Transient expression in HEK 293 cells: an alternative to E. coli for the production of secreted and intracellular mammalian proteins.

scientific article

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