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List of works by Sophia Khom

A cycloartane glycoside derived from Actaea racemosa L. modulates GABAA receptors and induces pronounced sedation in mice

scientific article

Alcohol dependence and withdrawal impair serotonergic regulation of GABA transmission in the rat central nucleus of the amygdala

scientific article published on 07 August 2020

Alcohol dependence potentiates substance P/neurokinin-1 receptor signaling in the rat central nucleus of amygdala

scientific article published on 18 March 2020

Analysis of β-Subunit-dependent GABAA Receptor Modulation and Behavioral Effects of Valerenic Acid Derivatives.

scientific article

Bioactivity-Guided Isolation of GABAA Receptor Modulating Constituents from the Rhizomes of Actaea racemosa ⬇️

scientific article published on November 17, 2010

CRF modulates glutamate transmission in the central amygdala of naïve and ethanol-dependent rats.

scientific article published on 11 August 2017

Cessation of fluoxetine treatment increases alcohol seeking during relapse and dysregulates endocannabinoid and glutamatergic signaling in the central amygdala

scientific article published on 24 July 2019

Design, synthesis and pharmacological evaluation of novel β2/3 subunit-selective γ-Aminobutyric Acid Type A (GABAA) receptor modulators

scientific article published on 23 October 2018

Developing piperine towards TRPV1 and GABAA receptor ligands--synthesis of piperine analogs via Heck-coupling of conjugated dienes

scientific article

Efficient modulation of γ-aminobutyric acid type A receptors by piperine derivatives

scientific article

Esters of valerenic acid as potential prodrugs.

scientific article

GABA(A) receptor modulators from the Chinese herbal drug Junci Medulla--the pith of Juncus effusus.

scientific article published on 23 January 2012

GABAA receptor modulation by piperine and a non-TRPV1 activating derivative

scientific article published on 25 April 2013

IL-1β expression is increased and regulates GABA transmission following chronic ethanol in mouse central amygdala

scientific article published on 26 October 2018

Identification and characterization of GABA(A) receptor modulatory diterpenes from Biota orientalis that decrease locomotor activity in mice.

scientific article published on 27 July 2011

Identification of the putative binding pocket of valerenic acid on GABAA receptors using docking studies and site-directed mutagenesis.

scientific article published on 16 September 2015

Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders

scientific article published on 21 October 2020

Increased IL-6 expression in astrocytes is associated with emotionality, alterations in central amygdala GABAergic transmission, and excitability during alcohol withdrawal

scientific article published on 19 August 2019

Modulation of GABAA receptors by valerian extracts is related to the content of valerenic acid.

scientific article

Oxytocin blocks enhanced motivation for alcohol in alcohol dependence and blocks alcohol effects on GABAergic transmission in the central amygdala

article

Pharmacological properties of GABAA receptors containing gamma1 subunits.

scientific article

Role of TLR4 in the Modulation of Central Amygdala GABA Transmission by CRF Following Restraint Stress.

scientific article published on 4 January 2018

The Role of the Central Amygdala in Alcohol Dependence

scientific article published on 27 January 2020

Valerenic acid derivatives as novel subunit-selective GABAA receptor ligands - in vitro and in vivo characterization

scientific article

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