List of works - Roberta Lattanzi

6-N,N-dimethylamino-2,3-naphthalimide: a new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides.

scientific article

A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists

scientific article published on 14 May 2014

A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic

scientific article

Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

scientific article

Antinociceptive activity of a novel buprenorphine analogue.

scientific article

Biological activities of Bv8 analogues.

scientific article published in November 2005

Bv8/PK2 and prokineticin receptors: a druggable pronociceptive system ⬇️

scientific article published on November 30, 2011

Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

scientific article

Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold

scientific article

Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals

scientific article published on 5 September 2014

Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration

scientific article published on 01 February 1999

Glycodermorphins: opioid peptides with potent and prolonged analgesic activity and enhanced blood-brain barrier penetration

scientific article

Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.

scientific article

Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.

scientific article

Modulators of pain: Bv8 and prokineticins.

scientific article published on July 2006

N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans

scientific article

New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands

scientific article

Novel glycosylated [Lys(7)]-dermorphin analogues: synthesis, biological activity and conformational investigations

scientific article published on 01 March 2007

PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice

scientific article published on 27 November 2014

Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

scientific article

Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem ⬇️

scientific article published on January 1, 2013

Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model

scientific article published on 5 January 2015

Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain

scientific article published on 18 March 2011

Respiratory and cardiovascular effects of the μ‐opioid receptor agonist [Lys7]dermorphin in awake rats ⬇️

scientific article published on May 1, 1998

Sensitization of transient receptor potential vanilloid 1 by the prokineticin receptor agonist Bv8.

scientific article published on May 2006

The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

scholarly article

The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1.

scientific article

The prokineticin receptor agonist Bv8 increases GABA release in the periaqueductal grey and modifies RVM cell activities and thermoceptive reflexes in the rat.

scientific article published on 14 November 2007

Triazine compounds as antagonists at Bv8-prokineticin receptors

scientific article

List of works by Roberta Lattanzi

6-N,N-dimethylamino-2,3-naphthalimide: a new environment-sensitive fluorescent probe in delta- and mu-selective opioid peptides.

A new convenient synthetic method and preliminary pharmacological characterization of triazinediones as prokineticin receptor antagonists

A new opioid designed multiple ligand derived from the micro opioid agonist endomorphin-2 and the delta opioid antagonist pharmacophore Dmt-Tic

Antagonism of the Prokineticin System Prevents and Reverses Allodynia and Inflammation in a Mouse Model of Diabetes

Antinociceptive activity of a novel buprenorphine analogue.

Biological activities of Bv8 analogues.

Bv8/PK2 and prokineticin receptors: a druggable pronociceptive system ⬇️

Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity

Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold

Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals

Dermorphin and deltorphin glycosylated analogues: synthesis and antinociceptive activity after systemic administration

Glycodermorphins: opioid peptides with potent and prolonged analgesic activity and enhanced blood-brain barrier penetration

Highly selective fluorescent analogue of the potent delta-opioid receptor antagonist Dmt-Tic.

Impaired nociception and inflammatory pain sensation in mice lacking the prokineticin receptor PKR1: focus on interaction between PKR1 and the capsaicin receptor TRPV1 in pain behavior.

Modulators of pain: Bv8 and prokineticins.

N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans

New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands

Novel glycosylated [Lys(7)]-dermorphin analogues: synthesis, biological activity and conformational investigations

PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice

Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice.

Peripheral administration of prokineticin 2 potently reduces food intake and body weight in mice via the brainstem ⬇️

Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model

Prokineticin receptor 1 antagonist PC-10 as a biomarker for imaging inflammatory pain

Respiratory and cardiovascular effects of the μ‐opioid receptor agonist [Lys7]dermorphin in awake rats ⬇️

Sensitization of transient receptor potential vanilloid 1 by the prokineticin receptor agonist Bv8.

The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

The prokineticin receptor agonist Bv8 decreases IL-10 and IL-4 production in mice splenocytes by activating prokineticin receptor-1.

The prokineticin receptor agonist Bv8 increases GABA release in the periaqueductal grey and modifies RVM cell activities and thermoceptive reflexes in the rat.

Triazine compounds as antagonists at Bv8-prokineticin receptors