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List of works by Wilhelmus Egbertus Arnout de Witte

A novel CCR2 antagonist inhibits atherogenesis in apoE deficient mice by achieving high receptor occupancy

scientific article

Assessment of Interspecies Differences in Drug-Induced QTc Interval Prolongation in Cynomolgus Monkeys, Dogs and Humans

scientific article

In vitro and in silico analysis of the effects of D receptor antagonist target binding kinetics on the cellular response to fluctuating dopamine concentrations

scientific article published on 21 September 2018

In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant

scientific article

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

scientific article

Mannopyranosyl uronic acid donor reactivity

scientific article published on 21 July 2011

Mechanistic models enable the rational use of in vitro drug-target binding kinetics for better drug effects in patients

scientific article

The influence of drug distribution and drug-target binding on target occupancy: The rate-limiting step approximation

scientific article

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