List of works - Fernanda Roleira

Activation of hydrocinnamic acids with pentafluorophenol versus pentafluorothiophenol: Reactivity towards hexylamine

Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells.

scientific article

Antioxidants and Stroke: Success and Pitfalls

article

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships

scientific article published on 26 March 2019

Characterization of polymeric nanoparticles for intravenous delivery: Focus on stability

scientific article published on 29 October 2016

Combined dual effect of modulation of human neutrophils' oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

scientific article published on 30 May 2016

Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.

scientific article published on 13 March 2013

Development of a new gas chromatography-mass spectrometry (GC-MS) methodology for the evaluation of 5α-reductase activity.

scientific article published on 2 January 2013

Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line.

scientific article published on 28 September 2014

Exploring new chemical functionalities to improve aromatase inhibition of steroids.

scientific article published on 26 April 2016

Isocratic HPLC Separation of Scopoletin andCis/TransIsomers of Ferulic Acid as Well as Isoscopoletin andCis/TransIsomers of Isoferulic Acid

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells

scientific article published on 28 April 2011

New Structure–Activity Relationships of A- and D-Ring Modified Steroidal Aromatase Inhibitors: Design, Synthesis, and Biochemical Evaluation

scientific article published on 18 April 2012

Plant derived and dietary phenolic antioxidants: anticancer properties.

scientific article published on 18 March 2015

Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.

scientific article

Simultaneous Isocratic HPLC Separation of the Diastereoisomers of Caffeic, Ferulic, and Isoferulic Acids and Related Coumarins

Steroidal aromatase inhibitors inhibit growth of hormone-dependent breast cancer cells by inducing cell cycle arrest and apoptosis.

scientific article published on November 2013

Structure-activity relationships of new A,D-ring modified steroids as aromatase inhibitors: design, synthesis, and biological activity evaluation.

scientific article

Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors.

scientific article published on 17 July 2008

X-ray and deuterium labeling studies on the abnormal ring cleavages of a 5 beta-epoxide precursor of formestane.

scientific article published in March 2002

List of works by Fernanda Roleira

Activation of hydrocinnamic acids with pentafluorophenol versus pentafluorothiophenol: Reactivity towards hexylamine

Anti-tumor efficacy of new 7α-substituted androstanes as aromatase inhibitors in hormone-sensitive and resistant breast cancer cells.

Antioxidants and Stroke: Success and Pitfalls

C-6α- vs C-7α-Substituted Steroidal Aromatase Inhibitors: Which Is Better? Synthesis, Biochemical Evaluation, Docking Studies, and Structure-Activity Relationships

Characterization of polymeric nanoparticles for intravenous delivery: Focus on stability

Combined dual effect of modulation of human neutrophils' oxidative burst and inhibition of colon cancer cells proliferation by hydroxycinnamic acid derivatives

Design, synthesis and biochemical studies of new 7α-allylandrostanes as aromatase inhibitors.

Development of a new gas chromatography-mass spectrometry (GC-MS) methodology for the evaluation of 5α-reductase activity.

Exemestane metabolites: Synthesis, stereochemical elucidation, biochemical activity and anti-proliferative effects in a hormone-dependent breast cancer cell line.

Exploring new chemical functionalities to improve aromatase inhibition of steroids.

Isocratic HPLC Separation of Scopoletin andCis/TransIsomers of Ferulic Acid as Well as Isoscopoletin andCis/TransIsomers of Isoferulic Acid

Lipophilic caffeic and ferulic acid derivatives presenting cytotoxicity against human breast cancer cells

New Structure–Activity Relationships of A- and D-Ring Modified Steroidal Aromatase Inhibitors: Design, Synthesis, and Biochemical Evaluation

Plant derived and dietary phenolic antioxidants: anticancer properties.

Simple coumarins and analogues in medicinal chemistry: occurrence, synthesis and biological activity.

Simultaneous Isocratic HPLC Separation of the Diastereoisomers of Caffeic, Ferulic, and Isoferulic Acids and Related Coumarins

Steroidal aromatase inhibitors inhibit growth of hormone-dependent breast cancer cells by inducing cell cycle arrest and apoptosis.

Structure-activity relationships of new A,D-ring modified steroids as aromatase inhibitors: design, synthesis, and biological activity evaluation.

Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors.

X-ray and deuterium labeling studies on the abnormal ring cleavages of a 5 beta-epoxide precursor of formestane.