List of works by Nicholas A Saunders

A novel E2F/sphingosine kinase 1 axis regulates anthracycline response in squamous cell carcinoma.

scientific article

A systematic review and meta-analysis of immunohistochemical biomarkers that differentiate chromophobe renal cell carcinoma from renal oncocytoma.

scientific article published on 7 March 2016

AP-2 transcription factor family member expression, activity, and regulation in human epidermal keratinocytes in vitro

scientific article published on 01 June 2004

Auranofin improves overall survival when combined with standard of care in a pilot study involving dogs with osteosarcoma

scientific article published on 23 August 2019

Auranofin is a potent suppressor of osteosarcoma metastasis.

scientific article published on 9 November 2015

CD62L as a therapeutic target in chronic lymphocytic leukemia.

scientific article published on 15 August 2013

Calcium enhances mouse keratinocyte differentiation in vitro to differentially regulate expression of papillomavirus authentic and codon modified L1 genes

scientific article published on 25 April 2007

Cavin-1/PTRF alters prostate cancer cell-derived extracellular vesicle content and internalization to attenuate extracellular vesicle-mediated osteoclastogenesis and osteoblast proliferation

scientific article

Cisplatin treatment induces a transient increase in tumorigenic potential associated with high interleukin-6 expression in head and neck squamous cell carcinoma.

scientific article published on 3 August 2010

Confluence-Induced Squamous Differentiation Is Not Accompanied by Changes in H3K27me3 Repressive Epigenetic Mark

scientific article published on 04 May 2015

Correction: HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients

scientific article published on 22 December 2020

Cytochrome P450, CYP26AI, is expressed at low levels in human epidermal keratinocytes and is not retinoic acid-inducible

scientific article (publication date: September 1999)

DUX4 Is Derepressed in Late-Differentiating Keratinocytes in Conjunction with Loss of H3K9me3 Epigenetic Repression

scientific article published on 09 February 2016

Dysregulation of epidermal growth factor receptor in actinic keratosis and squamous cell carcinoma.

scientific article published on 18 December 2014

Dysregulation of the repressive H3K27 trimethylation mark in head and neck squamous cell carcinoma contributes to dysregulated squamous differentiation

scientific article published on 27 November 2012

E2F modulates keratinocyte squamous differentiation: implications for E2F inhibition in squamous cell carcinoma.

scientific article published on 15 May 2003

E2F6: a member of the E2F family that does not modulate squamous differentiation.

scientific article

E2F7 can regulate proliferation, differentiation, and apoptotic responses in human keratinocytes: implications for cutaneous squamous cell carcinoma formation

scientific article

Early diagnostic biomarkers for esophageal adenocarcinoma--the current state of play.

scientific article published on 10 April 2013

Epithelial expression of human papillomavirus type 16 E7 protein results in peripheral CD8 T-cell suppression mediated by CD4+CD25+ T cells

scientific article published on 01 February 2009

Exploiting novel cell cycle targets in the development of anticancer agents.

scientific article

Expression of papillomavirus L1 proteins regulated by authentic gene codon usage is favoured in G2/M-like cells in differentiating keratinocytes

scientific article published on 20 January 2010

Extracellular vesicles secreted by highly metastatic clonal variants of osteosarcoma preferentially localize to the lungs and induce metastatic behaviour in poorly metastatic clones.

scientific article published on 02 June 2016

Fetuin-A promotes primary keratinocyte migration: independent of epidermal growth factor receptor signalling.

scientific article

Fetuin-A: A Major Fetal Serum Protein that Promotes “Wound Closure” and Scarless Healing

scientific article published on 25 October 2007

Focal overexpression of CEACAM6 contributes to enhanced tumourigenesis in head and neck cancer via suppression of apoptosis

scientific article

Functional characterization of cultured cells derived from an intraepidermal carcinoma of the skin (IEC-1).

scientific article published on August 2000

Gene codon composition determines differentiation-dependent expression of a viral capsid gene in keratinocytes in vitro and in vivo

scientific article

Generalized substitution of isoencoding codons shortens the duration of papillomavirus L1 protein expression in transiently gene-transfected keratinocytes due to cell differentiation

scientific article (publication date: 2007)

Glyco-centric lectin magnetic bead array (LeMBA) - proteomics dataset of human serum samples from healthy, Barrett׳s esophagus and esophageal adenocarcinoma individuals.

scientific article published on April 2016

HDAC7 is an actionable driver of therapeutic antibody resistance by macrophages from CLL patients

scientific article published on 24 July 2020

High serum levels of CD178 (soluble FasL) predict for inferior progression free survival in chronic lymphocytic leukemia treated with fludarabine-based chemotherapy

scientific article published on 25 June 2019

Histone deacetylase inhibitors specifically kill nonproliferating tumour cells

scientific article published on September 2004

Histone hyperacetylation induced by histone deacetylase inhibitors is not sufficient to cause growth inhibition in human dermal fibroblasts

scientific article published on 13 April 2001

Identifying molecular targets mediating the anticancer activity of histone deacetylase inhibitors: a work in progress.

scientific article

Inactivation of glutathione peroxidase activity contributes to UV-induced squamous cell carcinoma formation

scientific article published on 01 May 2007

Increased FcγRIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients.

scientific article published on 17 October 2016

Indole-3-carbinol - induced growth inhibition can be converted to a cytotoxic response in the presence of TPA+Ca(2+) in squamous cell carcinoma cell lines

scientific article published on 16 July 2007

Inhibition of cervical cancer cell growth in vitro and in vivo with lentiviral-vector delivered short hairpin RNA targeting human papillomavirus E6 and E7 oncogenes.

scientific article

Isolation (from a basal cell carcinoma) of a functionally distinct fibroblast-like cell type that overexpresses Ptch.

scientific article

Laminin 10/11: an alternative adhesive ligand for epidermal keratinocytes with a functional role in promoting proliferation and migration

scientific article published on October 2002

Loss of E2F7 expression is an early event in squamous differentiation and causes derepression of the key differentiation activator Sp1.

scientific article published on 20 January 2011

Loss of osteoclasts contributes to development of osteosarcoma pulmonary metastases.

scientific article published on 7 September 2010

Modulation of proliferation-specific and differentiation-specific markers in human keratinocytes by SMAD7.

scientific article published on April 2004

Molecular and cellular biology of basal cell carcinoma.

scientific article

Morphological and molecular analysis of a breast cancer cluster at the ABC Studio in Toowong

scientific article published on 01 August 2012

No association between HPV positive breast cancer and expression of human papilloma viral transcripts

scientific article

Non-melanoma skin cancers

Optimization of a transplant model to assess skin reconstitution from stem cell-enriched primary human keratinocyte populations

scientific article published on 01 January 2005

Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone

scientific article

PI3K-p110δ contributes to antibody responses by macrophages in chronic lymphocytic leukemia

scientific article published on 28 August 2019

Preclinical evaluation of dual PI3K-mTOR inhibitors and histone deacetylase inhibitors in head and neck squamous cell carcinoma

scientific article

Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis.

scientific article published on 28 August 2015

RNA interference against human papillomavirus oncogenes in cervical cancer cells results in increased sensitivity to cisplatin.

scientific article published on 24 August 2005

RacGAP1 Is a Novel Downstream Effector of E2F7-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma.

scientific article published on 27 May 2015

Regulation of proliferation-specific and differentiation-specific genes during senescence of human epidermal keratinocyte and mammary epithelial cells

scientific article published on 01 November 1993

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

scientific article

Serum Glycoprotein Biomarker Discovery and Qualification Pipeline Reveals Novel Diagnostic Biomarker Candidates for Esophageal Adenocarcinoma.

scientific article

Short interfering RNA induced generation and translation of stable 5' mRNA cleavage intermediates.

scientific article published on 16 June 2016

Simplifying the molecular mechanisms of human papillomavirus.

scientific article published in October 1998

Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas

scientific article published on 01 June 2018

The role of osteoclasts and tumour-associated macrophages in osteosarcoma metastasis

scientific article

Transcriptomic analysis of monocytes and macrophages derived from CLL patients which display differing abilities to respond to therapeutic antibody immune complexes.

scientific article published on 11 November 2015

Tumor-initiating activity and tumor morphology of HNSCC is modulated by interactions between clonal variants within the tumor

scientific article published on 26 July 2010

Up-regulated expression of Sp1 protein coincident with a viral protein in human and mouse differentiating keratinocytes may act as a cell differentiation marker.

scientific article

Valproic acid as a therapeutic agent for head and neck squamous cell carcinomas.

scientific article published on 9 April 2008

Valproic acid combined with cytosine arabinoside in elderly patients with acute myeloid leukemia has in vitro but limited clinical activity

scientific article published on 11 January 2012

Valproic acid: growth inhibition of head and neck cancer by induction of terminal differentiation and senescence.

scientific article published on 24 March 2011

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