List of works - Peter A.C. 't Hoen

A decline in PABPN1 induces progressive muscle weakness in oculopharyngeal muscle dystrophy and in muscle aging

scientific article published on June 2013

Cell-type specific regulation of myostatin signaling

scientific article

Tissue-specific transcript annotation and expression profiling with complementary next-generation sequencing technologies.

scientific article

A 3 months mild functional test regime does not affect disease parameters in young mdx mice.

scientific article published on 21 March 2010

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy

scientific article

DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts

scientific article

Accurate quantification of dystrophin mRNA and exon skipping levels in duchenne muscular dystrophy.

scientific article published on 10 May 2010

Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

scientific article published on 29 March 2018

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

scientific article

Addendum: The FAIR Guiding Principles for scientific data management and stewardship

article by Mark D Wilkinson et al published 19 March 2019 in Scientific Data

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data

scientific article

Literature-aided interpretation of gene expression data with the weighted global test

scientific article

Non-sequential and multi-step splicing of the dystrophin transcript.

scientific article published on 15 December 2015

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Literature-based priors for gene regulatory networks.

scientific article published on 23 April 2009

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP).

scientific article published on 22 January 2013

Gene expression variation between mouse inbred strains

scientific article

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells

scientific article published on 28 May 2018

Intensity-based analysis of two-colour microarrays enables efficient and flexible hybridization designs.

scientific article published on 24 February 2004

Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.

scientific article published on 7 August 2014

BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

scientific article published on 16 October 2010

Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy

scientific article

Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease

scientific article

Gene expression profiling to monitor therapeutic and adverse effects of antisense therapies for Duchenne muscular dystrophy

scientific article

Skewed X-inactivation is common in the general female population

scientific article published on 14 December 2018

204th ENMC International Workshop on Biomarkers in Duchenne Muscular Dystrophy 24–26 January 2014, Naarden, The Netherlands

scientific article published on September 11, 2014

DMD transcript imbalance determines dystrophin levels

scientific article published on 23 August 2013

Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling

scientific article

Combined effect of AAV-U7-induced dystrophin exon skipping and soluble activin Type IIB receptor in mdx mice

scientific article published on 24 September 2012

Gene expression profiling highlights defective myogenesis in DMD patients and a possible role for bone morphogenetic protein 4.

scientific article

RNA sequencing: from tag-based profiling to resolving complete transcript structure

scientific article

Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples

scientific article published on 27 July 2016

Antisense-oligonucleotide mediated exon skipping in activin-receptor-like kinase 2: inhibiting the receptor that is overactive in fibrodysplasia ossificans progressiva

scientific article

Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

scientific article (publication date: 21 March 2017)

Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides

scientific article published on 21 January 2014

Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy

scientific article

PhD7Faster: predicting clones propagating faster from the Ph.D.-7 phage display peptide library

scientific article published on 21 January 2014

An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

scientific article published on 7 April 2017

Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor

scientific article

Microarray retriever: a web-based tool for searching and large scale retrieval of public microarray data

scientific article

Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine

scientific article published on 31 March 2016

Structuring research methods and data with the research object model: genomics workflows as a case study

scientific article

Genetics of the human metabolome, what is next?

scientific article published in October 2014

Interspecies translation of disease networks increases robustness and predictive accuracy.

scientific article

Systematic genomic and translational efficiency studies of uveal melanoma

scientific article

The Implicitome: A Resource for Rationalizing Gene-Disease Associations

scientific article

A SNP panel for identification of DNA and RNA specimens

scientific article

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

scientific article published on 23 September 2014

In silico discovery and experimental validation of new protein-protein interactions

scientific article (publication date: 31 January 2011)

Comprehensive gene-expression survey identifies wif1 as a modulator of cardiomyocyte differentiation

scientific article

List of works by Peter A.C. 't Hoen

A decline in PABPN1 induces progressive muscle weakness in oculopharyngeal muscle dystrophy and in muscle aging

Cell-type specific regulation of myostatin signaling

Tissue-specific transcript annotation and expression profiling with complementary next-generation sequencing technologies.

A 3 months mild functional test regime does not affect disease parameters in young mdx mice.

Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy

DeepSAGE reveals genetic variants associated with alternative polyadenylation and expression of coding and non-coding transcripts

Accurate quantification of dystrophin mRNA and exon skipping levels in duchenne muscular dystrophy.

Full-length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

Aging as accelerated accumulation of somatic variants: whole-genome sequencing of centenarian and middle-aged monozygotic twin pairs

Addendum: The FAIR Guiding Principles for scientific data management and stewardship

PASSion: a pattern growth algorithm-based pipeline for splice junction detection in paired-end RNA-Seq data

Literature-aided interpretation of gene expression data with the weighted global test

Non-sequential and multi-step splicing of the dystrophin transcript.

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

Literature-based priors for gene regulatory networks.

Inhibition of IL-1 Signaling by Antisense Oligonucleotide-mediated Exon Skipping of IL-1 Receptor Accessory Protein (IL-1RAcP).

Gene expression variation between mouse inbred strains

Immune stimuli shape the small non-coding transcriptome of extracellular vesicles released by dendritic cells

Intensity-based analysis of two-colour microarrays enables efficient and flexible hybridization designs.

Downregulation of the acetyl-CoA metabolic network in adipose tissue of obese diabetic individuals and recovery after weight loss.

BMP antagonists enhance myogenic differentiation and ameliorate the dystrophic phenotype in a DMD mouse model

Timing and localization of human dystrophin isoform expression provide insights into the cognitive phenotype of Duchenne muscular dystrophy

Literature-aided meta-analysis of microarray data: a compendium study on muscle development and disease

Gene expression profiling to monitor therapeutic and adverse effects of antisense therapies for Duchenne muscular dystrophy

Skewed X-inactivation is common in the general female population

204th ENMC International Workshop on Biomarkers in Duchenne Muscular Dystrophy 24–26 January 2014, Naarden, The Netherlands

DMD transcript imbalance determines dystrophin levels

Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling

Combined effect of AAV-U7-induced dystrophin exon skipping and soluble activin Type IIB receptor in mdx mice

Gene expression profiling highlights defective myogenesis in DMD patients and a possible role for bone morphogenetic protein 4.

RNA sequencing: from tag-based profiling to resolving complete transcript structure

Integration of targeted metabolomics and transcriptomics identifies deregulation of phosphatidylcholine metabolism in Huntington's disease peripheral blood samples

Antisense-oligonucleotide mediated exon skipping in activin-receptor-like kinase 2: inhibiting the receptor that is overactive in fibrodysplasia ossificans progressiva

Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s disease

Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides

Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy

PhD7Faster: predicting clones propagating faster from the Ph.D.-7 phage display peptide library

An alanine expanded PABPN1 causes increased utilization of intronic polyadenylation sites

Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor

Microarray retriever: a web-based tool for searching and large scale retrieval of public microarray data

Cortical Spreading Depression Causes Unique Dysregulation of Inflammatory Pathways in a Transgenic Mouse Model of Migraine

Structuring research methods and data with the research object model: genomics workflows as a case study

Genetics of the human metabolome, what is next?

Interspecies translation of disease networks increases robustness and predictive accuracy.

Systematic genomic and translational efficiency studies of uveal melanoma

The Implicitome: A Resource for Rationalizing Gene-Disease Associations

A SNP panel for identification of DNA and RNA specimens

Regulation of skeletal muscle energy/nutrient-sensing pathways during metabolic adaptation to fasting in healthy humans.

In silico discovery and experimental validation of new protein-protein interactions

Comprehensive gene-expression survey identifies wif1 as a modulator of cardiomyocyte differentiation