List of works - Jesper M Mathiesen

A cAMP Biosensor-Based High-Throughput Screening Assay for Identification of Gs-Coupled GPCR Ligands and Phosphodiesterase Inhibitors.

scientific article

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity

scientific article published on 25 June 2010

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

scientific article published on 28 February 2007

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

scientific article

Crystal structure of the β2 adrenergic receptor-Gs protein complex

scientific article

Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.

scientific article published on 3 May 2005

Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators.

scientific article

Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits

scientific article published on 01 November 2006

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

scientific article

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

scientific article

Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

scientific article published on 16 August 2012

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

scientific article

Real-time trafficking and signaling of the glucagon-like peptide-1 receptor

scientific article published on 22 November 2013

Structural insights into differences in G protein activation by family A and family B GPCRs

scientific article

Structure-activity relationships for negative allosteric mGluR5 modulators

scientific article

Structures of metabotropic GABAB receptor

scientific article published on 24 June 2020

The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation

scientific article

cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

scientific article published on 01 January 2013

mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery

scientific article

List of works by Jesper M Mathiesen

A cAMP Biosensor-Based High-Throughput Screening Assay for Identification of Gs-Coupled GPCR Ligands and Phosphodiesterase Inhibitors.

A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation

Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.

Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators.

Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits

Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators

Positive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEP

Real-time trafficking and signaling of the glucagon-like peptide-1 receptor

Structural insights into differences in G protein activation by family A and family B GPCRs

Structure-activity relationships for negative allosteric mGluR5 modulators

Structures of metabotropic GABAB receptor

The metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activation

cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors

mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery