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List of works by Erik Danen

3D Cell-Based Assays for Drug Screens: Challenges in Imaging, Image Analysis, and High-Content Analysis

scientific article published on 28 February 2019

A guide to mechanobiology: Where biology and physics meet

scientific article published on 18 May 2015

A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer.

scientific article published in March 2017

Adverse outcome pathways: opportunities, limitations and open questions

scientific article published on 19 October 2017

Alpha v-integrins in human melanoma: gain of alpha v beta 3 and loss of alpha v beta 5 are related to tumor progression in situ but not to metastatic capacity of cell lines in nude mice

scientific article published on 01 May 1995

Automated microinjection of cell-polymer suspensions in 3D ECM scaffolds for high-throughput quantitative cancer invasion screens.

scientific article

Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma.

scientific article

BMP-7 inhibits TGF-β-induced invasion of breast cancer cells through inhibition of integrin β(3) expression.

scientific article

Beyond the Influence of <i>IDH</i> Mutations: Exploring Epigenetic Vulnerabilities in Chondrosarcoma

scientific article published on 30 November 2020

Binding of soluble fibronectin to integrin alpha5 beta1 - link to focal adhesion redistribution and contractile shape.

scientific article

Cancer-Associated Mutations of the Adenosine A2A Receptor Have Diverse Influences on Ligand Binding and Receptor Functions

scientific article published on 22 July 2022

Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour.

scientific article published on 17 August 2016

Combining doublecortin-like kinase silencing and vinca alkaloids results in a synergistic apoptotic effect in neuroblastoma cells.

scientific article

Comparative Proton and Photon Irradiation Combined with Pharmacological Inhibitors in 3D Pancreatic Cancer Cultures

scientific article published on 31 October 2020

Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies

scientific article

Correction

scholarly article published in Journal of Cell Biology

Crosstalk between Hypoxia and Extracellular Matrix in the Tumor Microenvironment in Breast Cancer

scientific article published in 2022

Cytoskeletal Anisotropy Controls Geometry and Forces of Adherent Cells

scientific article published in Physical Review Letters

Deciphering Epithelial-Mesenchymal Transition Regulatory Networks in Cancer through Computational Approaches

scientific article

Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis

scientific article

Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity

scientific article published on 20 April 2014

E-cadherin expression in human melanoma

scientific article published on 01 April 1996

Emergence of alpha 5 beta 1 fibronectin- and alpha v beta 3 vitronectin-receptor expression in melanocytic tumour progression

scientific article published on 01 March 1994

Establishment and characterization of an uveal-melanoma cell line.

scientific article published on July 1995

Evolutionary conservation of the 14-3-3 protein

scientific article published on May 15, 1992

Expression of CD44 and the pattern of CD44 alternative splicing in uveal melanoma.

scientific article published on February 1996

Expression of CD44 splice variants in human cutaneous melanoma and melanoma cell lines is related to tumor progression and metastatic potential

scientific article published on 01 June 1995

Generation of antimelanoma cytotoxic T lymphocytes from healthy donors after presentation of melanoma-associated antigen-derived epitopes by dendritic cells in vitro

scientific article published on 01 November 1995

Glycoconjugate profile and CD44 expression in human melanoma cell lines with different metastatic capacity.

scientific article published in April 1995

High-throughput live cell imaging of apoptosis

scientific article published on 01 June 2010

Hypoxia Triggers TAZ Phosphorylation in Basal A Triple Negative Breast Cancer Cells

scientific article published on 4 September 2022

IGF1R signaling drives antiestrogen resistance through PAK2/PIX activation in luminal breast cancer.

scientific article published on 22 January 2018

Identification of cisplatin-regulated metabolic pathways in pluripotent stem cells

scientific article (publication date: 2013)

Ignoring matrix boundaries when the LKB1 master kinase is gone.

scientific article published on October 2014

Inhibition of PARP Sensitizes Chondrosarcoma Cell Lines to Chemo- and Radiotherapy Irrespective of the IDH1 or IDH2 Mutation Status

scientific article published on 02 December 2019

Inhibition of mutant IDH1 decreases D-2-HG levels without affecting tumorigenic properties of chondrosarcoma cell lines.

scientific article

Integrin beta 3 cDNA transfection into a highly metastatic alpha v beta 3-negative human melanoma cell line inhibits invasion and experimental metastasis.

scientific article published on September 1996

Integrin expression in uveal melanoma differs from cutaneous melanoma

scientific article published on 01 December 1993

Integrin signaling in control of tumor growth and progression

scientific article published on February 18, 2013

Integrin switching modulates adhesion dynamics and cell migration

scientific article published on 30 April 2009

Integrins control motile strategy through a Rho-cofilin pathway.

scientific article

Integrins in regulation of tissue development and function

scientific article published on 01 December 2003

Integrins in regulation of tissue development and function.

scientific article

Integrins: regulators of tissue function and cancer progression.

scientific article

Loss of adhesion to basement membrane components but not to keratinocytes in proliferating melanocytes

scientific article published on 01 May 1996

MEK inhibition induces apoptosis in osteosarcoma cells with constitutive ERK1/2 phosphorylation.

scientific article

Mechanisms of melanoma cell adhesion to fibronectin

scientific article published on 01 August 1995

NAD Synthesis Pathway Interference Is a Viable Therapeutic Strategy for Chondrosarcoma.

scientific article published on 31 August 2017

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.

scientific article published on 3 July 2012

No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone

scientific article

Pharmacological inhibition of Bcl-xL sensitizes osteosarcoma to doxorubicin

scientific article

Properties of metastasizing and nonmetastasizing human melanoma cells.

scientific article

RGD-independent cell adhesion via a tissue transglutaminase-fibronectin matrix promotes fibronectin fibril deposition and requires syndecan-4/2 α5β1 integrin co-signaling

scientific article

Regulation of integrin-mediated adhesion to laminin and collagen in human melanocytes and in non-metastatic and highly metastatic human melanoma cells

scientific article published on 01 May 1993

Role of integrins as signal transducing cell adhesion molecules in human cutaneous melanoma.

scientific article published on January 1995

SYK is a candidate kinase target for the treatment of advanced prostate cancer.

scientific article

Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.

scientific article published on 21 April 2010

Systems microscopy approaches to understand cancer cell migration and metastasis.

scientific article

Targeted radiosensitization in prostate cancer.

scientific article published on January 2013

Targeting survivin as a potential new treatment for chondrosarcoma of bone

scientific article published on 9 May 2016

The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.

scientific article

The cancer stem cell microenvironment and anti-cancer therapy.

scientific article

The disintegrin eristostatin interferes with integrin alpha 4 beta 1 function and with experimental metastasis of human melanoma cells

scientific article published on 01 January 1998

The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions.

scientific article published on 6 February 2015

The interaction of SRC kinase with beta3 integrin tails: a potential therapeutic target in thrombosis and cancer.

scientific article published on 15 June 2010

The regulation of MacMARCKS expression by integrin beta3.

scientific article published on 12 January 2007

Unraveling DNA damage response-signaling networks through systems approaches

scientific article published on August 13, 2013

p140Cap suppresses the invasive properties of highly metastatic MTLn3-EGFR cells via impaired cortactin phosphorylation.

scientific article published on 4 July 2011

β1 integrin inhibition elicits a prometastatic switch through the TGFβ-miR-200-ZEB network in E-cadherin-positive triple-negative breast cancer.

scientific article published on 11 February 2014