List of works - Brion W Murray

A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase

scientific article published on 01 March 1997

A simple and efficient maleimide-based approach for peptide extension with a cysteine-containing peptide phage library.

scientific article

Analysis of pharmacologic inhibitors of Jun N-terminal kinases.

scientific article published in January 2001

Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models.

scientific article

Characterizing the effects of the juxtamembrane domain on vascular endothelial growth factor receptor-2 enzymatic activity, autophosphorylation, and inhibition by axitinib.

scientific article

Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic Probes for glycosyltransferases

scientific article published on 01 August 2000

Countering Breast Cancer's Counterpunch

scientific article published on 01 October 2019

Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases

scientific article published in February 2004

Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyraz

scientific article

Discovery of pyrroloaminopyrazoles as novel PAK inhibitors

scientific article

Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

scientific article published on June 2009

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation ⬇️

scientific article published on October 31, 1997

Mechanism and specificity of human alpha-1,3-fucosyltransferase V.

scientific article published on August 1996

Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of Tie2 and phospho-Tie2

scientific article

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors ⬇️

scientific article published on September 17, 2012

Molecular properties of pyruvate formate-lyase activating enzyme.

scientific article published on December 1993

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

scientific article

PAK signaling in oncogenesis.

scientific article published on 25 May 2009

Protein kinase biochemistry and drug discovery.

scientific article published on 03 August 2011

Protein-inhibitor complexes analyzed by alkaline capillary LC-MS.

scientific article published in October 2005

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

scientific article

Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.

scientific article published in February 2008

Structure-based design of novel human Pin1 inhibitors (I)

scientific article

Structure-based design of novel human Pin1 inhibitors (II)

scientific article

Substrate-specific conformational regulation of the receptor tyrosine kinase VEGFR2 catalytic domain.

scientific article published on 6 March 2013

Tumor P-Glycoprotein Correlates with Efficacy of PF-3758309 in in vitro and in vivo Models of Colorectal Cancer ⬇️

scientific article published on March 22, 2013

Why is CMP-ketodeoxyoctonate highly unstable?

scientific article published on January 1997

p38-2, a novel mitogen-activated protein kinase with distinct properties.

scientific article

List of works by Brion W Murray

A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase

A simple and efficient maleimide-based approach for peptide extension with a cysteine-containing peptide phage library.

Analysis of pharmacologic inhibitors of Jun N-terminal kinases.

Association of the epithelial-to-mesenchymal transition phenotype with responsiveness to the p21-activated kinase inhibitor, PF-3758309, in colon cancer models.

Characterizing the effects of the juxtamembrane domain on vascular endothelial growth factor receptor-2 enzymatic activity, autophosphorylation, and inhibition by axitinib.

Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic Probes for glycosyltransferases

Countering Breast Cancer's Counterpunch

Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases

Discovery of a novel class of exquisitely selective mesenchymal-epithelial transition factor (c-MET) protein kinase inhibitors and identification of the clinical candidate 2-(4-(1-(quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyraz

Discovery of pyrroloaminopyrazoles as novel PAK inhibitors

Enzymatic characterization of c-Met receptor tyrosine kinase oncogenic mutants and kinetic studies with aminopyridine and triazolopyrazine inhibitors.

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation ⬇️

Mechanism and specificity of human alpha-1,3-fucosyltransferase V.

Mechanistic effects of autophosphorylation on receptor tyrosine kinase catalysis: enzymatic characterization of Tie2 and phospho-Tie2

Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors ⬇️

Molecular properties of pyruvate formate-lyase activating enzyme.

Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3.

PAK signaling in oncogenesis.

Protein kinase biochemistry and drug discovery.

Protein-inhibitor complexes analyzed by alkaline capillary LC-MS.

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

Steady-state and pre-steady-state kinetic evaluation of severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro cysteine protease: development of an ion-pair model for catalysis.

Structure-based design of novel human Pin1 inhibitors (I)

Structure-based design of novel human Pin1 inhibitors (II)

Substrate-specific conformational regulation of the receptor tyrosine kinase VEGFR2 catalytic domain.

Tumor P-Glycoprotein Correlates with Efficacy of PF-3758309 in in vitro and in vivo Models of Colorectal Cancer ⬇️

Why is CMP-ketodeoxyoctonate highly unstable?

p38-2, a novel mitogen-activated protein kinase with distinct properties.